2009
Xenobiotic Metabolizing Gene Variants, Dietary Heterocyclic Amine Intake, and Risk of Prostate Cancer
Koutros S, Berndt SI, Sinha R, Ma X, Chatterjee N, Alavanja MC, Zheng T, Huang WY, Hayes RB, Cross AJ. Xenobiotic Metabolizing Gene Variants, Dietary Heterocyclic Amine Intake, and Risk of Prostate Cancer. Cancer Research 2009, 69: 1877-1884. PMID: 19223546, PMCID: PMC2662592, DOI: 10.1158/0008-5472.can-08-2447.Peer-Reviewed Original ResearchConceptsProstate cancer riskProstate cancerOdds ratioCancer riskSingle nucleotide polymorphismsDietary Heterocyclic Amine IntakeOvarian Cancer Screening TrialHeterocyclic amine intakeCancer Screening TrialUnconditional logistic regressionCase-control studyDietary heterocyclic aminesProstate cancer casesHeterocyclic aminesHCA intakeCancer casesLow intakeScreening TrialHCA metabolismMalignant transformationLogistic regressionCancerIntakeGene variantsConfidence intervals
2005
RAS mutation is associated with hyperdiploidy and parental characteristics in pediatric acute lymphoblastic leukemia
Wiemels JL, Zhang Y, Chang J, Zheng S, Metayer C, Zhang L, Smith MT, Ma X, Selvin S, Buffler PA, Wiencke JK. RAS mutation is associated with hyperdiploidy and parental characteristics in pediatric acute lymphoblastic leukemia. Leukemia 2005, 19: 415-419. PMID: 15674422, DOI: 10.1038/sj.leu.2403641.Peer-Reviewed Original ResearchConceptsRAS mutationsMaternal ageLeukemia casesPediatric acute lymphoblastic leukemiaAcute lymphoblastic leukemia casesDiagnostic bone marrow samplesIncident leukemia casesPaternal preconception smokingNorthern California Childhood Leukemia StudyAcute lymphoblastic leukemiaLymphoblastic leukemia casesBone marrow samplesKRAS codon 12California Childhood Leukemia StudyRAS gene mutationsChildhood Leukemia StudyEtiology of subtypesPreconception smokingCase seriesLymphoblastic leukemiaLeukemia patientsMultivariable modelMarrow samplesHigh hyperdiploidyChildhood leukemia