2018
Epidemiology of myelodysplastic syndromes: Why characterizing the beast is a prerequisite to taming it
Zeidan AM, Shallis RM, Wang R, Davidoff A, Ma X. Epidemiology of myelodysplastic syndromes: Why characterizing the beast is a prerequisite to taming it. Blood Reviews 2018, 34: 1-15. PMID: 30314642, DOI: 10.1016/j.blre.2018.09.001.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsConceptsCase ascertainmentAllogeneic hematopoietic stem cell transplantationAnnual age-adjusted incidenceHematopoietic stem cell transplantationOutcomes of patientsAge-adjusted incidenceStem cell transplantationAcute myeloid leukemiaTraditional morphologic assessmentClassification of MDSVariable cytopeniasCell transplantationMyelodysplastic syndromePrior receiptInefficient hematopoiesisEffective therapyMale genderRisk factorsMyeloid leukemiaEpidemiological trendsTreatment decisionsMyeloid neoplasmsEpidemiological assessmentDiagnostic criteriaTemporal improvement
2016
In utero cytomegalovirus infection and development of childhood acute lymphoblastic leukemia
Francis SS, Wallace AD, Wendt GA, Li L, Liu F, Riley LW, Kogan S, Walsh KM, de Smith AJ, Dahl GV, Ma X, Delwart E, Metayer C, Wiemels JL. In utero cytomegalovirus infection and development of childhood acute lymphoblastic leukemia. Blood 2016, 129: 1680-1684. PMID: 27979823, PMCID: PMC5364339, DOI: 10.1182/blood-2016-07-723148.Peer-Reviewed Original ResearchConceptsAcute lymphoblastic leukemiaCMV infectionCytomegalovirus infectionLymphoblastic leukemiaChildhood acute lymphoblastic leukemiaUtero cytomegalovirus infectionCongenital CMV infectionCommon childhood cancerActive viral transcriptionBone marrow specimensNon-Hispanic whitesTiming of infectionNewborn blood samplesEtiologic roleRisk factorsChildhood cancerHealthy controlsHigh prevalenceMarrow specimensLeukemia blastsBlood samplesPrenatal originEtiologic agentInfectionHispanic children
2014
Disease Risk Estimation by Combining Case–Control Data with Aggregated Information on the Population at Risk
Chang X, Waagepetersen R, Yu H, Ma X, Holford TR, Wang R, Guan Y. Disease Risk Estimation by Combining Case–Control Data with Aggregated Information on the Population at Risk. Biometrics 2014, 71: 114-121. PMID: 25351292, PMCID: PMC4782587, DOI: 10.1111/biom.12256.Peer-Reviewed Original ResearchConceptsCase-control dataUnbiased estimating equationsFinite sample performanceNovel statistical frameworkSummary statisticsAsymptotic propertiesPopulation Estimates ProgramStatistical frameworkSubstantive applicationsEstimating EquationsEquationsStatisticsStandard approachEstimationEstimates ProgramEstimatorRisk estimationSimulationsApproach
2012
Epidemiology of Myelodysplastic Syndromes
Ma X. Epidemiology of Myelodysplastic Syndromes. The American Journal Of Medicine 2012, 125: s2-s5. PMID: 22735748, PMCID: PMC3394456, DOI: 10.1016/j.amjmed.2012.04.014.Peer-Reviewed Original ResearchConceptsMyelodysplastic syndromeIncidence of MDSBetter risk-stratify patientsClonal hematopoietic stem cell malignanciesHematopoietic stem cell malignanciesRisk-stratify patientsStem cell malignanciesMore effective treatmentsMDS prognosisDifferent comorbiditiesPrognostic factorsSignificant morbidityEtiologic factorsDisease burdenPoor survivalEffective treatmentCell malignanciesHigh mortalityNew casesHeterogeneous groupComorbiditiesSyndromeDiseaseRecent studiesPotential interactions
2008
Jakking up tumor registry reporting of the myeloproliferative neoplasms
Selinger HA, Ma X. Jakking up tumor registry reporting of the myeloproliferative neoplasms. American Journal Of Hematology 2008, 84: 124-126. PMID: 19117021, DOI: 10.1002/ajh.21333.Peer-Reviewed Original ResearchPrevalence of polycythemia vera and essential thrombocythemia
Ma X, Vanasse G, Cartmel B, Wang Y, Selinger HA. Prevalence of polycythemia vera and essential thrombocythemia. American Journal Of Hematology 2008, 83: 359-362. PMID: 18181200, DOI: 10.1002/ajh.21129.Peer-Reviewed Original ResearchConceptsPrevalence of PVPolycythemia veraEssential thrombocythemiaMyeloproliferative disordersUS populationAge-standardized prevalenceHealth claims dataAge-specific prevalenceLarge US populationEntire US populationClaims dataET patientsInsurance payerHealth claimsLogistic regressionPrevalencePatientsMedicaid ServicesMolecular etiologyCommon typeThrombocythemiaDisordersUnited StatesAffected populationVera