2020
Ovarian BDNF promotes survival, migration, and attachment of tumor precursors originated from p53 mutant fallopian tube epithelial cells
Kang M, Chong KY, Hartwich TMP, Bi F, Witham AK, Patrick D, Morrisson MJ, Cady SL, Cerchia AP, Kelk D, Liu Y, Nucci J, Madarikan O, Ueno D, Shuch BM, Yang-Hartwich Y. Ovarian BDNF promotes survival, migration, and attachment of tumor precursors originated from p53 mutant fallopian tube epithelial cells. Oncogenesis 2020, 9: 55. PMID: 32471985, PMCID: PMC7260207, DOI: 10.1038/s41389-020-0243-y.Peer-Reviewed Original ResearchHigh-grade serous ovarian carcinomaBrain-derived neurotrophic factorFallopian tube epitheliumFTE cellsTumor precursorsPathophysiological processesTropomyosin receptor kinase BFallopian tube epithelial cellsBDNF/TrkBReceptor kinase BLethal gynecological malignancyGenetic alterationsSerous ovarian carcinomaFunction mutationsCommon TP53Gynecological malignanciesNeurotrophic factorFallopian tubeOvarian carcinomaRisk factorsFollicular fluidMutant p53 proteinVivo modelTP53 lossEpithelial cells
2011
An In Vitro Model for the Study of Human Implantation
Holmberg JC, Haddad S, Wünsche V, Yang Y, Aldo PB, Gnainsky Y, Granot I, Dekel N, Mor G. An In Vitro Model for the Study of Human Implantation. American Journal Of Reproductive Immunology 2011, 67: 169-178. PMID: 22151560, PMCID: PMC3703643, DOI: 10.1111/j.1600-0897.2011.01095.x.Peer-Reviewed Original ResearchConceptsHuman implantationTrophoblast cellsImmortalized human endometrial stromal cellsStromal cellsHuman endometrial stromal cellsFirst trimester trophoblast cellsEpithelial cellsEndometrial stromal cellsCo-culture experimentsVitro modelUterine implantationImplantationLow attachment platesCellsMolecular aspectsInvasionAttachment platesCulture mediumHelpful tool