2014
Epigenome-wide analysis of piRNAs in gene-specific DNA methylation
Fu A, Jacobs D, Zhu Y. Epigenome-wide analysis of piRNAs in gene-specific DNA methylation. RNA Biology 2014, 11: 1301-1312. PMID: 25590657, PMCID: PMC4615395, DOI: 10.1080/15476286.2014.996091.Peer-Reviewed Original ResearchConceptsPIWI-interacting RNAsGene-specific DNA methylationDNA methylationGenic lociTransposable elementsCpG sitesSilencing of transposable elementsGenome-wide methylation profilingDifferentially methylated CpG sitesGenome-wide effortsTarget CpG sitesInduce DNA methylationTransposon classesEpigenome-wide analysisIntergenic regionGenomic regionsNascent mRNAHuman genomeMethylation changesGenomic DNAMethylation profilesHuman somatic cellsUnique speciesGenome copiesSomatic cells
2011
Genome-wide methylation changes in night working women in Denmark: same altered promoter methylation of CLOCK and CRY2 as in breast cancer cases
Zhu Y, Stevens R, Hoffman A, Tjonneland A, Vogal U, Zheng T, Hansen J. Genome-wide methylation changes in night working women in Denmark: same altered promoter methylation of CLOCK and CRY2 as in breast cancer cases. Occupational And Environmental Medicine 2011, 68: a18. DOI: 10.1136/oemed-2011-100382.56.Peer-Reviewed Original ResearchGenome-wide methylation analysisMethylation patternsGenome-wide methylation changesMethylation analysisDifferential promoter methylationCore circadian genesPromoter methylationIngenuity Pathway AnalysisCancer-related pathwaysAltered promoter methylationMethylation chipDNA replicationEpigenetic impactMethylation changesEpigenetic changesGene promoterMethylation alterationsEpigenetic effectsCancer relevanceGene expressionPathway analysisCircadian genesRelevant transcriptsAssociation analysisPromoter hypomethylation