2019
Endogenous development of Cystoisospora belli in intestinal and biliary epithelium of humans
Dubey JP, Evason KJ, Walther Z. Endogenous development of Cystoisospora belli in intestinal and biliary epithelium of humans. Parasitology 2019, 146: 865-872. PMID: 30859916, DOI: 10.1017/s003118201900012x.Peer-Reviewed Original ResearchMeSH KeywordsAdultBiliary TractBiopsyCoccidiosisDuodenumEpithelial CellsHumansIsosporaLife Cycle StagesMaleMerozoitesOocystsYoung AdultConceptsBiliary epitheliumC. belliEpithelial cellsCystoisospora belliSingle parasitophorous vacuoleDuodenal biopsiesBiliary tractDepressed immunityPAS-positive granulesHistopathologic diagnosisHost epithelial cellsBiopsy samplesDigestive disordersSame PVParasitophorous vacuoleParasite multipliesCertain inclusionTransmission cycleEpitheliumCoccidian parasitesAsexual stagesBelliMerozoitesCellsOocysts
2008
A PDZ‐Binding Motif Controls Basolateral Targeting of Syndecan‐1 Along the Biosynthetic Pathway in Polarized Epithelial Cells
Maday S, Anderson E, Chang HC, Shorter J, Satoh A, Sfakianos J, Fölsch H, Anderson JM, Walther Z, Mellman I. A PDZ‐Binding Motif Controls Basolateral Targeting of Syndecan‐1 Along the Biosynthetic Pathway in Polarized Epithelial Cells. Traffic 2008, 9: 1915-1924. PMID: 18764819, PMCID: PMC2820280, DOI: 10.1111/j.1600-0854.2008.00805.x.Peer-Reviewed Original ResearchMeSH KeywordsAmino Acid MotifsAnimalsBasement MembraneCell LineDogsEpithelial CellsGene Knockdown TechniquesMutationPDZ DomainsSyndecan-1ConceptsPolarized epithelial cellsBiosynthetic pathwayPDZ domain-containing proteinsType II PDZDomain-containing proteinsPDZ-Binding MotifSyndecan-1Cell surface proteoglycansEpithelial cellsBasolateral targetingNormal epithelial morphologyBasolateral domainMotif leadPlasma membranePDZBasolateral localizationSurface proteoglycansBasolateral surfaceApical surfaceEpithelial morphologyMotifPotential rolePathwayCellsMislocalization
1998
Human CASK/LIN-2 Binds Syndecan-2 and Protein 4.1 and Localizes to the Basolateral Membrane of Epithelial Cells
Cohen A, Wood D, Marfatia S, Walther Z, Chishti A, Anderson J. Human CASK/LIN-2 Binds Syndecan-2 and Protein 4.1 and Localizes to the Basolateral Membrane of Epithelial Cells. Journal Of Cell Biology 1998, 142: 129-138. PMID: 9660868, PMCID: PMC2133028, DOI: 10.1083/jcb.142.1.129.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsCalcium-Calmodulin-Dependent Protein KinasesCarrier ProteinsCloning, MolecularCytoskeletal ProteinsEpithelial CellsGuanylate KinasesHelminth ProteinsHumansMembrane GlycoproteinsMembrane ProteinsMicrofilament ProteinsNeuropeptidesNucleoside-Phosphate KinaseProteoglycansRabbitsRatsRecombinant Fusion ProteinsSpectrinSyndecan-2ConceptsProtein 4.1LIN-2Membrane domainsRas/MAP kinase pathwayMembrane-associated guanylate kinase (MAGUK) familySyndecan-2Membrane-associated guanylate kinaseVulval precursor cellsTwo-hybrid screenBasal plasma membrane domainsPlasma membrane domainsExtracellular matrixCASK/LINHeparan sulfate proteoglycan syndecan-2Basal membrane domainsMAP kinase pathwayProteoglycan syndecan-2Receptor tyrosine kinasesDifferent epithelial cell typesEpithelial cell typesLET-23Caenorhabditis elegansPDZ domainActin cytoskeletonGuanylate kinase