2022
Skin dose distributions between Stanford and rotational techniques in total skin electron therapy (TSET)
Ding G, Chen Z, Zhong W, Zhu T. Skin dose distributions between Stanford and rotational techniques in total skin electron therapy (TSET). Medical Physics 2022, 49: 6646-6653. PMID: 35972019, DOI: 10.1002/mp.15907.Peer-Reviewed Original ResearchConceptsTotal skin electron therapyDose coverageStanford techniqueAdvanced-stage cutaneous T-cell lymphomaCutaneous T-cell lymphomaSkin dose distributionRotational techniqueT-cell lymphomaPatient's postureSimilar dose coverageDose distributionExtended treatment distancesElectron therapyMean doseEffective treatmentSame patientSmall dose differencesClinical settingPatient treatmentSkin dosesRealistic clinical settingsSkin doseDoseDifferent posturesDistribution of dose
2009
Monte Carlo Investigation of Stereotactic Radiosurgery of Spinal Metastases
Deng J, Chen Z, Knisely J, Decker R, Chiang V, Nath R. Monte Carlo Investigation of Stereotactic Radiosurgery of Spinal Metastases. IFMBE Proceedings 2009, 25/1: 13-16. DOI: 10.1007/978-3-642-03474-9_4.Peer-Reviewed Original ResearchSpinal metastasesStereotactic radiosurgeryDose-volume histogramsMean doseAnalytical anisotropic algorithmRisk of recurrenceTarget dose coverageDose distributionPencil beam convolutionSpinal cordDose coverageTarget dosePTV doseTreatment planMetastasisHomogeneity indexDoseRadiosurgeryPBC resultsPatientsTreatment planning systemPatient anatomyCommercial treatment planning systemDose discrepanciesAccurate dose distribution
2002
Edema-induced increase in tumour cell survival for 125I and 103Pd prostate permanent seed implants—a bio-mathematical model
Yue N, Chen Z, Nath R. Edema-induced increase in tumour cell survival for 125I and 103Pd prostate permanent seed implants—a bio-mathematical model. Physics In Medicine And Biology 2002, 47: 1185-1204. PMID: 11996063, DOI: 10.1088/0031-9155/47/7/313.Peer-Reviewed Original ResearchConceptsTumor potential doubling timeContinuous low dose rate irradiationTumor cell survivalSeed implantsBio-mathematical modelCell survivalExternal beam radiotherapyPresence of edemaProstate seed implantationLow dose rate irradiationEdema magnitudeEffects of edemaPotential doubling timeTypical edemaDose rate irradiationProstate volumeSurgical traumaPermanent seed implantsSeed implantationSignificant edemaTreatment strategiesSurgical proceduresBeam radiotherapyEdemaDose coverage
2000
Dosimetric effects of needle divergence in prostate seed implant using and radioactive seeds
Nath S, Chen Z, Yue N, Trumpore S, Peschel R. Dosimetric effects of needle divergence in prostate seed implant using and radioactive seeds. Medical Physics 2000, 27: 1058-1066. PMID: 10841410, DOI: 10.1118/1.598971.Peer-Reviewed Original ResearchConceptsMinimum target doseIodine-125 implantsTarget doseDose coverageTumor biological effective doseTarget dose coverageBiological effective doseBase of prostateRadioactive seedsProstate seed implantsProstate seedPalladium-103Target volumeEffective doseDosimetric qualityDosePatient implantsDosimetric effectsSeed implantsProstateImplantsMagnitude of degradationActual implantationNeedle orientationActual configuration
1999
Optimum timing for image-based dose evaluation of 125I and 103Pd prostate seed implants
Yue N, Chen Z, Peschel R, Dicker A, Waterman F, Nath R. Optimum timing for image-based dose evaluation of 125I and 103Pd prostate seed implants. International Journal Of Radiation Oncology • Biology • Physics 1999, 45: 1063-1072. PMID: 10571216, DOI: 10.1016/s0360-3016(99)00282-5.Peer-Reviewed Original ResearchConceptsDose-volume histogramsProstate volumeDose coverageConventional dose-volume histogramsSeed implantsEdema magnitudeMagnitude of edemaOptimum timingPostimplant dose-volume histogramDose evaluationOptimal patient managementProstate seed implantationPreimplant planImplant patientsPermanent brachytherapy implantsProstate seed implantsPatient managementProstate cancerSeed implantationSurgical proceduresEdemaProstateDose distributionDays postimplantationPatients
1998
Correlation of medical dosimetry quality indicators to the local tumor control in patients with prostate cancer treated with iodine‐125 interstitial implants
Nath R, Roberts K, Ng M, Peschel R, Chen Z. Correlation of medical dosimetry quality indicators to the local tumor control in patients with prostate cancer treated with iodine‐125 interstitial implants. Medical Physics 1998, 25: 2293-2307. PMID: 9874821, DOI: 10.1118/1.598440.Peer-Reviewed Original ResearchConceptsSurvival rateProstate cancerInterstitial implantsLocal recurrence-free survival rateRecurrence-free survival ratesLocal control rateLocal tumor controlExcellent clinical resultsProstate cancer patientsUnfavorable groupClinical efficacyCancer patientsControl rateTumor controlClinical resultsFavorable groupDose coveragePatientsDosimetric parametersDosimetry parametersIsodose surfaceSignificant differencesVirginia studyUnfavorable parametersCancer