2024
Detecting time‐varying genetic effects in Alzheimer's disease using a longitudinal genome‐wide association studies model
Zhuang X, Xu G, Amei A, Cordes D, Wang Z, Oh E, Initiative F. Detecting time‐varying genetic effects in Alzheimer's disease using a longitudinal genome‐wide association studies model. Alzheimer's & Dementia Diagnosis Assessment & Disease Monitoring 2024, 16: e12597. PMID: 38855650, PMCID: PMC11157162, DOI: 10.1002/dad2.12597.Peer-Reviewed Original ResearchGenome-wide association studiesSingle nucleotide polymorphismsLongitudinal genome-wide association studiesGWAS modelsAssociation studiesGenetic effectsAlzheimer's diseaseSingle nucleotide polymorphism effectsNational Alzheimer's Coordinating Center dataAge-dependent genetic effectsImpairment statusProgression of Alzheimer's diseaseEffects of apoEAge-stratified analysesGenetic signalsGenetic lociNucleotide polymorphismsLongitudinal phenotypesPathway analysisInitiative participantsAmyloid accumulationAmyloidStandardized uptake value ratioCenter dataAmyloid positron emission tomography
2020
tRFtarget: a database for transfer RNA-derived fragment targets
Li N, Shan N, Lu L, Wang Z. tRFtarget: a database for transfer RNA-derived fragment targets. Nucleic Acids Research 2020, 49: d254-d260. PMID: 33035346, PMCID: PMC7779015, DOI: 10.1093/nar/gkaa831.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsBase PairingBase SequenceCaenorhabditis elegansDatabases, Nucleic AcidDrosophila melanogasterGene OntologyHumansMiceMolecular Sequence AnnotationNucleic Acid ConformationNucleic Acid HybridizationRhodobacter sphaeroidesRNA, MessengerRNA, Small UntranslatedRNA, TransferSchizosaccharomycesThermodynamicsXenopusZebrafishConceptsTarget genesTransfer RNASmall non-coding RNAsGene Ontology annotationsNon-coding RNAsFunctional pathway analysisAccessible web-based databaseMolecular functionsOntology annotationsBiological functionsPathway analysisMolecular mechanismsPhysiological processesTarget predictionHuman diseasesGenesMRNA transcriptsRNAWeb-based databaseConvenient linkTRFImportant roleRNAhybridTargetIntaRNA