2024
Mediators of sex-specific differences in rates of stroke mimics among patients treated with intravenous thrombolysis: A nationwide analysis of 174,995 patients
Chen H, Khunte M, Colasurdo M, Chaturvedi S, Malhotra A, Gandhi D. Mediators of sex-specific differences in rates of stroke mimics among patients treated with intravenous thrombolysis: A nationwide analysis of 174,995 patients. Journal Of Stroke And Cerebrovascular Diseases 2024, 33: 108021. PMID: 39303869, DOI: 10.1016/j.jstrokecerebrovasdis.2024.108021.Peer-Reviewed Original ResearchRate of migraineNo cerebral infarctionPatients treated with intravenous thrombolysisRisk factorsIntravenous thrombolysisStroke mimicsMediation analysisICD-10 codesVascular risk factorsRetrospective cohort studyNational Inpatient Sample databaseIVT-treated patientsRates of stroke mimicsInpatient Sample databaseICD-10Cohort studyFemale patientsDemographic informationSex-specific differencesNationwide analysisCerebral infarctionPatientsSample databaseWomenMigraine
2023
Radiographic Signs of Advanced Cerebral Venous Thrombosis Negatively Modulate the Effectiveness of Endovascular Treatments
Chen H, Khunte M, Colasurdo M, Singh P, Malhotra A, Gandhi D. Radiographic Signs of Advanced Cerebral Venous Thrombosis Negatively Modulate the Effectiveness of Endovascular Treatments. Cerebrovascular Diseases 2023, 53: 519-526. PMID: 37931607, DOI: 10.1159/000534821.Peer-Reviewed Original ResearchCerebral venous thrombosisGood discharge outcomeEndovascular treatmentRadiographic signsCVT patientsHospital mortalityVenous thrombosisDischarge outcomesMedical managementBetter outcomesSevere cerebral venous thrombosisNational Inpatient Sample databaseConservative medical managementPatient selection practicesPresence of infarctionShort-term effectivenessEVT patientsEVT treatmentParenchymal manifestationsMedical comorbiditiesMultivariable adjustmentCerebral infarctionPatient demographicsSecondary outcomesHospitalization outcomesIntravenous thrombolysis prior to endovascular thrombectomy in elderly stroke patients: An analysis of the National Inpatient Sample database
Chen H, Khunte M, Colasurdo M, Malhotra A, Gandhi D. Intravenous thrombolysis prior to endovascular thrombectomy in elderly stroke patients: An analysis of the National Inpatient Sample database. Journal Of The Neurological Sciences 2023, 454: 120842. PMID: 37856997, DOI: 10.1016/j.jns.2023.120842.Peer-Reviewed Original ResearchConceptsNational Inpatient Sample databaseHospital mortalityHemorrhagic complicationsIntravenous thrombolysisEndovascular thrombectomyEVT patientsIVT treatmentThrombectomy centreElderly patientsMultivariable logistic regression modelSample databaseStroke risk factorsElderly stroke patientsCross-sectional studyLarge-scale cross-sectional studyOutcomes of interestHigh rateLogistic regression modelsPatients 80Medical comorbiditiesOnly patientsPatient demographicsStroke etiologyThrombolytic treatmentHemorrhagic riskNational Trends of Cerebral Venous Sinus Stenting for the Treatment of Idiopathic Intracranial Hypertension
Khunte M, Chen H, Colasurdo M, Chaturvedi S, Malhotra A, Gandhi D. National Trends of Cerebral Venous Sinus Stenting for the Treatment of Idiopathic Intracranial Hypertension. Neurology 2023, 101: 402-406. PMID: 36990721, PMCID: PMC10501094, DOI: 10.1212/wnl.0000000000207245.Peer-Reviewed Original ResearchConceptsVenous sinus stentingOptic nerve sheath fenestrationIdiopathic intracranial hypertensionIIH treatmentCSF shuntsIntracranial hypertensionSurgical proceduresCerebral venous sinus stentingNational Inpatient Sample databaseStandard medical treatmentCerebral venous sinusesNew surgical procedureRecent temporal trendsAdult patientsSheath fenestrationSinus stentingHospital characteristicsPractice patternsVenous sinusesMedical treatmentComparative effectivenessProcedure numbersPatientsSample databaseShunt
2022
Associations of Osteoarthritis With Thrombectomy Utilization and Outcomes for Large Vessel Acute Ischemic Stroke
Chen H, Khunte M, Colasurdo M, Jindal G, Malhotra A, Gandhi D, Chaturvedi S. Associations of Osteoarthritis With Thrombectomy Utilization and Outcomes for Large Vessel Acute Ischemic Stroke. Stroke 2022, 54: 518-526. PMID: 36541211, DOI: 10.1161/strokeaha.122.041749.Peer-Reviewed Original ResearchConceptsMultivariable logistic regression modelEndovascular thrombectomyAssociation of osteoarthritisLogistic regression modelsHospital mortalityMedical comorbiditiesIschemic strokeRisk factorsLower oddsLarge vessel acute ischemic strokeNational Inpatient Sample databaseMultivariable logistic regression analysisLarge-vessel ischemic strokeIntravenous thrombolysis treatmentStroke risk factorsAcute ischemic strokeIschemic stroke patientsPresence of osteoarthritisCause of disabilityCross-sectional studyLogistic regression analysisPatient selection practicesLarge-scale cross-sectional studyDirect risk factorEVT treatment307 The Hospital Frailty Risk Score Independently Predicts Increased Complication Rates and Healthcare Resource Utilization After Endovascular Treatment of Ruptured Aneurysms
Koo A, Elsamadicy A, Sarkozy M, Sherman J, Reeves B, Freedman I, Antonios J, Sujijantarat N, Renado D, Hebert R, Malhotra A, Matouk C. 307 The Hospital Frailty Risk Score Independently Predicts Increased Complication Rates and Healthcare Resource Utilization After Endovascular Treatment of Ruptured Aneurysms. Neurosurgery 2022, 68: 67-68. DOI: 10.1227/neu.0000000000001880_307.Peer-Reviewed Original ResearchHospital Frailty Risk ScoreNon-routine dischargeFrailty Risk ScoreEndovascular treatmentIntracranial aneurysmsPerioperative complicationsLower frailtyHospital costsRisk scoreNational Inpatient Sample databaseMean total hospital costMultivariate logistic regression analysisICD-10 diagnostic codesImpact of frailtyRetrospective cohort studyHealthcare resource utilizationEvaluation of patientsTotal hospital costsAdverse healthcare outcomesAdministrative hospital dataRuptured intracranial aneurysmLogistic regression analysisRegression analysisMultivariate regression analysisAdult patients