2020
Signaling Diversity Enabled by Rap1 and cAMP/PKA‐Regulated Plasma Membrane ERK with Distinct Temporal Dynamics
Keyes J, Ganesan A, Molinar-Inglis O, Hamidzadeh A, Ling M, Trejo J, Levchenko A, Zhang J. Signaling Diversity Enabled by Rap1 and cAMP/PKA‐Regulated Plasma Membrane ERK with Distinct Temporal Dynamics. The FASEB Journal 2020, 34: 1-1. DOI: 10.1096/fasebj.2020.34.s1.00680.Peer-Reviewed Original ResearchERK activityTemporal regulationPrecise temporal regulationMembrane protrusion dynamicsSequence-specific motifsSpecific subcellular locationsControl cell morphologyDifferent subcellular compartmentsMultiple cellular processesERK enzymatic activityCAMP/PKAERK biosensorEGF inducesKinase cascadeCellular processesExtracellular signalsSubcellular compartmentsSubcellular locationProtrusion dynamicsSubcellular regionsPlasma membraneSpecific motifsEnzymatic activityCell morphologyRap1
2009
Guided Cell Migration on Microtextured Substrates with Variable Local Density and Anisotropy
Kim D, Seo C, Han K, Kwon K, Levchenko A, Suh K. Guided Cell Migration on Microtextured Substrates with Variable Local Density and Anisotropy. Advanced Functional Materials 2009, 19: 1579-1586. DOI: 10.1002/adfm.200801174.Peer-Reviewed Original ResearchVariable local densityCell culture substratesCell elongationCell-material interfaceCell shapeMigration of cellsCell migrationCell morphologyCulture substrateMicrotextured SubstratesAdvanced tissue engineeringCell orientationCellsSingle experimentUV-assisted capillary force lithographyTissue engineeringSubstrate