2024
A Genome-wide Association Study of Susceptibility to Upper Urinary Tract Infections
Flatby H, Ravi A, Liyanarachi K, Afset J, Rasheed H, Brumpton B, Hveem K, Åsvold B, DeWan A, Solligård E, Damås J, Rogne T. A Genome-wide Association Study of Susceptibility to Upper Urinary Tract Infections. The Journal Of Infectious Diseases 2024, jiae231. PMID: 38713594, DOI: 10.1093/infdis/jiae231.Peer-Reviewed Original ResearchGenome-wide association studiesMichigan Genomics InitiativeAssociation studiesUpper UTIMendelian randomizationMR analysisUpper urinary tract infectionRisk factorsPotential causal risk factorsCardiometabolic risk factorsModifiable risk factorsSex-stratified analysesCausal risk factorUrinary tract infectionGenome-wideFemale-only analysisGenetic lociPotential causal relationshipGenome InitiativeHealth StudyUK BiobankHLA-DQA2LociTract infectionsSmoking score
2023
The genetic contribution of the X chromosome in age-related hearing loss
Naderi E, Cornejo-Sanchez D, Li G, Schrauwen I, Wang G, Dewan A, Leal S. The genetic contribution of the X chromosome in age-related hearing loss. Frontiers In Genetics 2023, 14: 1106328. PMID: 36896235, PMCID: PMC9988903, DOI: 10.3389/fgene.2023.1106328.Peer-Reviewed Original ResearchX chromosomeChromosome XGenome-wide significance levelMRNA expression analysisExpression analysisChromosomesAssociation analysisGenetic variantsCommon sensory impairmentGenetic contributionAnalysis of malesAge-related hearing lossHair cellsInner ear tissuesInner hair cellsUK BiobankARHLVariantsHuman inner ear tissueEar tissueGenesLociHeritabilitySex-stratified analysesCells