2024
Reading Between the Tabloids: An Objective Analysis of the Quality and Readability of Patient Encountered Online Material for Face Transplantation.
Boroumand S, Littleton A, Aregbe A, Gu E, Huelsboemer L, Stögner V, Lewis K, Kauke-Navarro M, Haykal S, Pomahac B. Reading Between the Tabloids: An Objective Analysis of the Quality and Readability of Patient Encountered Online Material for Face Transplantation. Journal Of Craniofacial Surgery 2024 PMID: 39471279, DOI: 10.1097/scs.0000000000010668.Peer-Reviewed Original ResearchNews sourcesOnline materialsNewsFace transplant programsThird-party sourcesReadability metricsFace transplantationReadabilityTransplant programsPost hoc Tukey multiple comparison testTukey's multiple comparison testMultiple comparison testReputable sourcesTabloidsReadability of online materialsAuthorshipOne-way ANOVATransplantationThird-party sitesJAMA benchmark criteriaDiscernmentEncountersJAMA benchmarksAn Update on the Survival of the First 50 Face Transplants Worldwide
Homsy P, Huelsboemer L, Barret J, Blondeel P, Borsuk D, Bula D, Gelb B, Infante-Cossio P, Lantieri L, Mardini S, Morelon E, Nasir S, Papay F, Petruzzo P, Rodriguez E, Özkan Ö, Özmen S, Pomahac B, Lassus P. An Update on the Survival of the First 50 Face Transplants Worldwide. JAMA Surgery 2024, 159 PMID: 39292472, PMCID: PMC11411447, DOI: 10.1001/jamasurg.2024.3748.Peer-Reviewed Original ResearchOverall survivalRejection episodesFace transplantationTransplanted graftsMedian follow-up timeAcute rejection episodesFollow-up timePredictors of survivalMulticenter cohort studyExtensive facial defectsEpisodes per yearLong-term survivalTransplant variablesFacial defectsNonpublished dataTransplant lossMedian numberFollow-upCohort studyReconstructive optionsPrimary outcomeSecondary outcomesTransplant survivalTransplantationTransplant centers
2022
The Value of Upper Extremity, face, and uterus transplantation: A Summit Conference
Tintle S, Shores J, Azari K, Tzakis A, Dearden M, Porrett P, Johannesson L, McDiarmid S, Pomahac B, Levin L. The Value of Upper Extremity, face, and uterus transplantation: A Summit Conference. Orthoplastic Surgery 2022, 10: 41-46. DOI: 10.1016/j.orthop.2022.08.008.Peer-Reviewed Original ResearchVascular composite allotransplantationComposite allotransplantationUpper extremityUterus transplantationAmerican SocietyMajor transplant centersTransplant centersConsensus guidelinesTransplant surgeonsTransplantation communityReconstructive transplantationTransplantationAllotransplantationReproductive medicineUniformed Services UniversityExtremitiesUnited StatesPanel membersHealth SciencesServices UniversityBethesda MDContraindicationsSurgeonsVideo Messaging to Increase Vascularized Composite Allograft Donation Willingness in United States Military Veterans
Rodrigue J, Shenkel J, Boger M, Pomahac B, Fleishman A. Video Messaging to Increase Vascularized Composite Allograft Donation Willingness in United States Military Veterans. Transplantation Direct 2022, 8: e1355. PMID: 36204186, PMCID: PMC9531254, DOI: 10.1097/txd.0000000000001355.Peer-Reviewed Original ResearchDonation willingnessVCA transplantationProportion of participantsMilitary veteransUnited States military veteransComposite allograft transplantationUS military veteransBrief educational videoAllograft transplantationGenitourinary organsPostintervention increaseTransplantationVCA donorsSignificant preVeteransEffectiveness of videoHigher proportionParticipantsOrgansEducational videoPrePostinterventionProportionExtremitiesT cell-attracting CCL18 chemokine is a dominant rejection signal during limb transplantation
Borges T, Abarzua P, Gassen R, Kollar B, Lima-Filho M, Aoyama B, Gluhova D, Clark R, Islam S, Pomahac B, Murphy G, Lian C, Talbot S, Riella L. T cell-attracting CCL18 chemokine is a dominant rejection signal during limb transplantation. Cell Reports Medicine 2022, 3: 100559. PMID: 35492875, PMCID: PMC9040185, DOI: 10.1016/j.xcrm.2022.100559.Peer-Reviewed Original ResearchConceptsLimb transplantationTransplant recipientsSkin antigen-presenting cellsSolid organ transplant recipientsAccelerated graft rejectionOrgan transplant recipientsSkin transplantation modelAntigen-presenting cellsLife-changing procedureImmunosuppressive approachesTh17 cellsGraft rejectionGreater immunogenicityCell infiltrationSkin biopsiesTransplantation modelSkin xenograftsChemokine CCL18Immune moleculesTransplantationCCL18RecipientsMolecular characterizationChemokinesCCR8 receptor
2020
Defining chronic rejection in vascularized composite allotransplantation—The American Society of Reconstructive Transplantation and International Society of Vascularized Composite Allotransplantation chronic rejection working group: 2018 American Society of Reconstructive Transplantation meeting report and white paper Research goals in defining chronic rejection in vascularized composite allotransplantation
Kaufman C, Kanitakis J, Weissenbacher A, Brandacher G, Mehra M, Amer H, Zelger B, Zelger B, Pomahac B, McDiarmid S, Cendales L, Morelon E. Defining chronic rejection in vascularized composite allotransplantation—The American Society of Reconstructive Transplantation and International Society of Vascularized Composite Allotransplantation chronic rejection working group: 2018 American Society of Reconstructive Transplantation meeting report and white paper Research goals in defining chronic rejection in vascularized composite allotransplantation. SAGE Open Medicine 2020, 8: 2050312120940421. PMID: 32704373, PMCID: PMC7361482, DOI: 10.1177/2050312120940421.Peer-Reviewed Original ResearchChronic rejectionComposite allograftsFunctional declineReconstructive transplantationComposite allotransplantationHistologic evidenceDe novo donor-specific antibodiesAmerican SocietyNovo donor-specific antibodiesNormal allograft functionDonor-specific antibodiesInternational SocietyVascularized Composite AllotransplantationAcute rejectionAllograft functionAllograft recipientsImmunosuppressive therapyTreatment regimensRisk factorsUterine transplantationUpper extremityMeeting reportAllograftsTransplantationClinical cases
2019
Blood proteome profiling using aptamer-based technology for rejection biomarker discovery in transplantation
Shubin A, Kollar B, Dillon S, Pomahac B, Libermann T, Riella L. Blood proteome profiling using aptamer-based technology for rejection biomarker discovery in transplantation. Scientific Data 2019, 6: 314. PMID: 31819064, PMCID: PMC6901551, DOI: 10.1038/s41597-019-0324-y.Peer-Reviewed Original ResearchConceptsDevastating facial injuriesSevere rejection episodesAcute transplant rejectionType of transplantationPeripheral blood serumSOMAscan proteomics platformSatisfactory treatment optionAcute rejectionRejection episodesTransplant statusTransplantation centersTransplant rejectionTreatment optionsBiomarker discoverySkin biopsiesClinical dataHigh riskFacial injuriesInvasive biomarkersTransplantationAptamer-based technologiesFace transplantationPatientsBlood serumSerum proteinsFive-Year Follow-up after Face Transplantation
Tasigiorgos S, Kollar B, Turk M, Perry B, Alhefzi M, Kiwanuka H, Nizzi M, Marty F, Chandraker A, Tullius S, Riella L, Pomahac B. Five-Year Follow-up after Face Transplantation. New England Journal Of Medicine 2019, 380: 2579-2581. PMID: 31141626, DOI: 10.1056/nejmc1810468.Peer-Reviewed Original ResearchFace transplantation
Sinha I, Vyas R, Pomahac B. Face transplantation. 2019, 379-382. DOI: 10.1093/med/9780199699537.003.0045.Peer-Reviewed Original ResearchReturn of sensationSevere traumatic injuryComposite tissue allotransplantationComposite tissue transplantationFacial composite tissue allotransplantationTransplanted allograftPost transplantationLifelong immunosuppressionMotor functionTraumatic injuryTissue allotransplantationPsychiatric issuesPatientsTissue transplantationInfection riskTransplantationFace transplantationFacial formImmunosuppressionAllograftsAllotransplantationInjuryPossible rejectionMonths
2018
Increased levels of circulating MMP3 correlate with severe rejection in face transplantation
Kollar B, Shubin A, Borges T, Tasigiorgos S, Win T, Lian C, Dillon S, Gu X, Wyrobnik I, Murphy G, Pomahac B, Libermann T, Riella L. Increased levels of circulating MMP3 correlate with severe rejection in face transplantation. Scientific Reports 2018, 8: 14915. PMID: 30297859, PMCID: PMC6175842, DOI: 10.1038/s41598-018-33272-7.Peer-Reviewed Original ResearchConceptsSevere rejectionFace transplantationLarge independent patient cohortsAcute rejection episodesAnti-rejection treatmentFirst postoperative yearLongitudinal serum samplesNon-invasive candidate biomarkersViable treatment optionSOMAscan proteomics platformIndependent patient cohortsFace transplant recipientsRejection episodesPostoperative yearTransplant recipientsDevastating injuriesMMP3 levelsTransplant rejectionHistological gradePatient cohortTreatment optionsSurrogate markerMMP3 proteinCandidate biomarkersTransplantationPediatric face transplantation
Dorante M, Tasigiorgos S, Pomahac B. Pediatric face transplantation. Current Opinion In Organ Transplantation 2018, 23: 598-604. PMID: 30080696, DOI: 10.1097/mot.0000000000000572.Peer-Reviewed Original ResearchConceptsFace transplantationPediatric hand transplantationImmunosuppression burdenRejection episodesDonor allograftsPatient demographicsPediatric patientsAppropriate patientsHand transplantationHand transplantTransplantationPediatric colleaguesPatientsYoung populationFace transplantSurgical innovationTransplantOutcomesSoftware‐based video analysis of functional outcomes of face transplantation
Fischer S, Diehm Y, Dorante M, Kotsougiani D, Kueckelhaus M, Alhefzi M, Bueno E, Pomahac B. Software‐based video analysis of functional outcomes of face transplantation. Microsurgery 2018, 39: 53-61. PMID: 30159931, DOI: 10.1002/micr.30360.Peer-Reviewed Original ResearchConceptsFace transplantationNormal populationAssessment of outcomesDifferent time pointsFunctional outcomeFacial movementsPatient's abilitySame patientTransplantationMouth openingOutcome assessmentPatientsValuable assessment toolOpen mouthEye closureTime pointsRetrospective assessmentMonthsLip purseFacial transplantationAssessment toolSound evidenceOutcomesNoseEyebrowsInnovations in reconstructive microsurgery: Reconstructive transplantation
Kollar B, Tasigiorgos S, Dorante M, Carty M, Talbot S, Pomahac B. Innovations in reconstructive microsurgery: Reconstructive transplantation. Journal Of Surgical Oncology 2018, 118: 800-806. PMID: 30098294, DOI: 10.1002/jso.25147.Peer-Reviewed Original ResearchConceptsReconstructive transplantationViable reconstructive optionPediatric transplantsUpper extremityLower extremitiesAbdominal wallReconstructive optionsAdditional proceduresReconstructive microsurgeryTransplantationFace transplantTransplantPresent review articleExtremitiesReview articlePatientsUterusNeckFacial Transplantation
Aycart M, Pomahac B. Facial Transplantation. DeckerMed Plastic Surgery 2018 DOI: 10.2310/ps.10073.Peer-Reviewed Original ResearchFacial transplantationMicrosurgical reconstructive techniquesShort-term resultsComposite tissue transplantationVascularized Composite AllotransplantationQuality of lifeConventional therapyFunctional outcomeTransplant surgeryLate outcomesReconstructive techniquesComposite allotransplantationTransplantationTissue transplantationNeck defectsClinical realityMedical communityRecipient evaluationImmunosuppressionCraniofacial surgerySurgeryComplex headOutcomesKey wordsMore experienceQuality of Life and Psychosocial Functioning 2 Years Following Facial Transplantation
Oser M, Nizzi M, Zinser J, Turk M, Epstein R, Bueno E, Gitlin D, Pomahac B. Quality of Life and Psychosocial Functioning 2 Years Following Facial Transplantation. Journal Of The Academy Of Consultation-Liaison Psychiatry 2018, 59: 591-600. PMID: 29861176, DOI: 10.1016/j.psym.2018.04.005.Peer-Reviewed Original ResearchConceptsPhysical health QoLDepressive symptomsHealth statusPhysical health-related QoLFace transplantationOverall depressive symptomsHealth-related QoLMental health QOLSubthreshold depressive symptomsSevere facial disfigurementFacial transplantationQuality of lifeImmunosuppression inductionMonths posttransplantationDepressive episodePhysical QoLHigh health statusPatientsTransplantationQoLPsychosocial functioningLife outcomesCeiling effectsFacial disfigurementSymptomsFacial restoration by transplantation
Kollar B, Pomahac B. Facial restoration by transplantation. The Surgeon 2018, 16: 245-249. PMID: 29490887, DOI: 10.1016/j.surge.2018.01.003.Peer-Reviewed Original ResearchConceptsWorld War I.World War IIModern plastic surgerySir Harold GilliesPeter Bent Brigham HospitalWar IIFace transplantationFirst successful kidney transplantationJoseph MurraySuccessful kidney transplantationNobel PrizeWorldFacial restorationKidney transplantationTransplant cohortUnique patientsWomen's HospitalSkin graftsOrgan transplantationTransplantationHospitalPlastic surgeonsPlastic surgerySoldiersBattlefield
2017
Tissue conservation for transplantation
Krezdorn N, Tasigiorgos S, Wo L, Turk M, Lopdrup R, Kiwanuka H, Win T, Bueno E, Pomahac B. Tissue conservation for transplantation. Innovative Surgical Sciences 2017, 2: 171-187. PMID: 31579751, PMCID: PMC6754021, DOI: 10.1515/iss-2017-0010.Peer-Reviewed Original ResearchOrgan preservationLong-term allograft functionPreservation of organsStatic cold storageAllograft functionSubsequent reperfusionIschemic preconditioningPathophysiological changesMechanical perfusionTransplantationTissue conservationCurrent literature pointsTherapeutic additivesGold standardPreservation protocolsOrgansCurrent bodyTissueReperfusionIschemiaInjuryPerfusionThe Effects of Lip-Closure Exercise on Lip Strength and Function Following Full Facial Transplantation: A Case Report
Perry B, Richburg B, Pomahac B, Bueno E, Green J. The Effects of Lip-Closure Exercise on Lip Strength and Function Following Full Facial Transplantation: A Case Report. American Journal Of Speech-Language Pathology 2017, 26: 682-686. PMID: 28654949, DOI: 10.1044/2017_ajslp-16-0101.Peer-Reviewed Original ResearchConceptsLip strengthFacial transplantationPatient-reported outcomesFull facial transplantationRange of motionStrength training exercisesSevere facial disfigurementPreliminary findingsExercise programAdditional researchCase reportOutcome measuresClinical measuresSingle patientMotor impairmentTransplantationClinical casesPatientsFacial disfigurementExerciseEfficacyNew optionsSpeech intelligibilityExpressionSwallowingFirst Lower Two-Thirds Osteomyocutaneous Facial Allograft Perfused by a Unilateral Facial Artery
Fischer S, Lee T, Krezdorn N, Alhefzi M, Kueckelhaus M, Bueno E, Pomahac B. First Lower Two-Thirds Osteomyocutaneous Facial Allograft Perfused by a Unilateral Facial Artery. Plastic & Reconstructive Surgery 2017, 139: 1175e-1183e. PMID: 28445377, DOI: 10.1097/prs.0000000000003288.Peer-Reviewed Original ResearchConceptsFacial arteryFacial allograftImmunosuppressive therapyRejection episodesAirway volumeVenous outflowCLINICAL QUESTION/LEVELDual immunosuppressive therapyFacial allotransplantationTwo-thirdsMaintenance therapyMycophenolate mofetilSteroid pulseArtery anastomosisSurgical durationFacial functionTracheostomy tubeContralateral sideVascular anastomosisSubmental arteryTransplantationArteryAllograftsVascularization patternFacial form
2016
2598: Experience with patient referrals for upper extremity transplantation at a US academic medical center
Kiwanuka H, Aycart M, Bueno E, Pomahac B, Talbot S. 2598: Experience with patient referrals for upper extremity transplantation at a US academic medical center. Vascularized Composite Allotransplantation 2016, 3: 11-11. DOI: 10.1080/23723505.2016.1234211.Peer-Reviewed Original Research