2019
SAT-LB041 Insulin and IGF-2 Equally Regulate Placental Triglyceride Content
Anam A, Cooke K, O'Bryan J, Flannery C. SAT-LB041 Insulin and IGF-2 Equally Regulate Placental Triglyceride Content. Journal Of The Endocrine Society 2019, 3: sat-lb041. PMCID: PMC6552031, DOI: 10.1210/js.2019-sat-lb041.Peer-Reviewed Original ResearchPlacental lipid metabolismLean womenIGF-2Triglyceride contentLipid metabolismIGF-1Maternal triglyceride levelsMean age 34.4Elective C-sectionTime of presentationInsulin receptor isoformsMultiple comparison testColorimetric spectrophotometerNeonatal complicationsPlacenta explantsMaternal obesityNeonatal adiposityPlacental lipid contentMaternal insulinObese womenPregnant womenTG levelsTriglyceride levelsEndocrine SocietyVillous explants
2018
Mitogenic Insulin Receptor A Increases in the Rodent Pituitary at the Onset of Puberty
SALEH F, TAYLOR H, FLANNERY C. Mitogenic Insulin Receptor A Increases in the Rodent Pituitary at the Onset of Puberty. Diabetes 2018, 67 DOI: 10.2337/db18-245-lb.Peer-Reviewed Original ResearchOnset of pubertyIGF-1RFVB/NJ miceIGF-1R levelsPhysiological insulin resistanceWeek old micePeri-pubertal girlsPituitary hormone productionT-testInitiation of pubertyStudent's t-testSteroid hormone synthesisActive folliculogenesisHPO axisOvarian axisInsulin resistanceRisk factorsReceptor expressionIGF-1Normal insulinOld miceVaginal openingPuberty developmentHormone productionSplice variant isoforms