2019
SAT-LB041 Insulin and IGF-2 Equally Regulate Placental Triglyceride Content
Anam A, Cooke K, O'Bryan J, Flannery C. SAT-LB041 Insulin and IGF-2 Equally Regulate Placental Triglyceride Content. Journal Of The Endocrine Society 2019, 3: sat-lb041. PMCID: PMC6552031, DOI: 10.1210/js.2019-sat-lb041.Peer-Reviewed Original ResearchPlacental lipid metabolismLean womenIGF-2Triglyceride contentLipid metabolismIGF-1Maternal triglyceride levelsMean age 34.4Elective C-sectionTime of presentationInsulin receptor isoformsMultiple comparison testColorimetric spectrophotometerNeonatal complicationsPlacenta explantsMaternal obesityNeonatal adiposityPlacental lipid contentMaternal insulinObese womenPregnant womenTG levelsTriglyceride levelsEndocrine SocietyVillous explants
2016
Development of a Quantitative PCR Assay for Detection of Human Insulin-Like Growth Factor Receptor and Insulin Receptor Isoforms
Flannery CA, Rowzee AM, Choe GH, Saleh FL, Radford CC, Taylor HS, Wood TL. Development of a Quantitative PCR Assay for Detection of Human Insulin-Like Growth Factor Receptor and Insulin Receptor Isoforms. Endocrinology 2016, 157: 1702-1708. PMID: 26862994, PMCID: PMC4816738, DOI: 10.1210/en.2015-1698.Peer-Reviewed Original ResearchConceptsSplice variantsInsulin-like growth factor (IGF) ligandsInsulin-like growth factor receptorGrowth factor ligandsSpecific molecular signaturesQuantitative PCR assaysGrowth factor receptorHigh homologyMRNA sequencesQuantitative RT-PCRIGF-1 receptorFactor ligandInsulin receptor isoformsCompetition assaysPrimer pairsRelative abundanceInsulin receptorMolecular signaturesCell typesDifferent tissuesIGF-1R mRNAFactor receptorExpression levelsGel electrophoresisReceptor isoforms