The Intraflagellar Transport Protein IFT27 Promotes BBSome Exit from Cilia through the GTPase ARL6/BBS3
Liew GM, Ye F, Nager AR, Murphy JP, Lee JS, Aguiar M, Breslow DK, Gygi SP, Nachury MV. The Intraflagellar Transport Protein IFT27 Promotes BBSome Exit from Cilia through the GTPase ARL6/BBS3. Developmental Cell 2014, 31: 265-278. PMID: 25443296, PMCID: PMC4255629, DOI: 10.1016/j.devcel.2014.09.004.Peer-Reviewed Original ResearchConceptsCargo entryBardet-Biedl syndrome proteinsIntraflagellar transport (IFT) machineryBiochemical reconstitution assaysNucleotide-free formCiliary exitTransport machinerySyndrome proteinGTP loadingUnbiased proteomicsCoat assemblyReconstitution assaysBBSomeARL6IFT27CiliaBBS3AssemblyProteomicsMachineryProteinCargoSortingExitActivation