2019
Photodynamic therapy for cutaneous squamous cell carcinoma in situ: Impact of anatomic location, tumor diameter, and incubation time on effectiveness
Kibbi N, Zhang Y, Leffell DJ, Christensen SR. Photodynamic therapy for cutaneous squamous cell carcinoma in situ: Impact of anatomic location, tumor diameter, and incubation time on effectiveness. Journal Of The American Academy Of Dermatology 2019, 82: 1124-1130. PMID: 31712171, DOI: 10.1016/j.jaad.2019.10.079.Peer-Reviewed Original ResearchMeSH KeywordsAgedAged, 80 and overAminolevulinic AcidAnalysis of VarianceBiopsy, NeedleCarcinoma in SituCarcinoma, Squamous CellCohort StudiesDisease-Free SurvivalFemaleHumansImmunohistochemistryLogistic ModelsMaleMiddle AgedMultivariate AnalysisNeoplasm InvasivenessNeoplasm StagingPhotochemotherapyPrognosisRetrospective StudiesSkin NeoplasmsSurvival AnalysisTreatment OutcomeTumor BurdenConceptsCutaneous squamous cell carcinomaALA incubation timeSquamous cell carcinomaTumor diameterALA-PDTSubsequent recurrenceCell carcinomaAnatomic locationInitial complete response ratePhotodynamic therapyCases of SCCISMultivariate analysis factorsComplete response rateMedical record reviewEffectiveness of PDTPatient demographicsClinical responseMedian timeRetrospective reviewRecord reviewRetrospective studyTreatment detailsSingle institutionEffective treatmentResponse rate
2015
Indoor Tanning and the MC1R Genotype: Risk Prediction for Basal Cell Carcinoma Risk in Young People
Molinaro AM, Ferrucci LM, Cartmel B, Loftfield E, Leffell DJ, Bale AE, Mayne ST. Indoor Tanning and the MC1R Genotype: Risk Prediction for Basal Cell Carcinoma Risk in Young People. American Journal Of Epidemiology 2015, 181: 908-916. PMID: 25858289, PMCID: PMC4445390, DOI: 10.1093/aje/kwu356.Peer-Reviewed Original ResearchConceptsRisk prediction modelCancer risk prediction modelsIndoor tanningBasal cell carcinoma incidenceBasal cell carcinoma riskNovel risk prediction modelRisk of BCCRisk predictionCase-control studyNon-Hispanic whitesLogistic regression modelsCancer risk predictionSignificant morbidityCarcinoma incidenceAdjusted areaCarcinoma riskIndependent cohortYoung individualsTreatment costsMC1R variantsYoung peopleReceptor geneCharacteristic curve
2014
Tea, coffee, and caffeine and early-onset basal cell carcinoma in a case–control study
Ferrucci LM, Cartmel B, Molinaro AM, Leffell DJ, Bale AE, Mayne ST. Tea, coffee, and caffeine and early-onset basal cell carcinoma in a case–control study. European Journal Of Cancer Prevention 2014, 23: 296-302. PMID: 24841641, PMCID: PMC4059399, DOI: 10.1097/cej.0000000000000037.Peer-Reviewed Original ResearchConceptsEarly-onset basal cell carcinomaBasal cell carcinomaCase-control studyCell carcinomaDermatopathology databaseOdds ratioRegular consumptionRisk of BCCMultivariate odds ratiosSquamous cell carcinomaUnconditional logistic regressionConfidence intervalsModest protective effectHot teaNon-Hispanic whitesPotential health benefitsEpidemiologic evidenceInverse associationProtective effectBiopsy siteAge 40Caffeinated coffeeSkin carcinogenesisBCC casesProtective role