2024
Short-Term Out-of-Pocket and Total Costs of Care After Ablation, Resection, or Transplant for Early-Stage Hepatocellular Carcinoma: A National SEER-Medicare Cost Comparison.
Charalel R, Mushlin A, Zheng X, Mao J, Carlos R, Brown R, Ibrahim S, Fortune B, Talenfeld A, Madoff D, Johnson M, Sedrakyan A. Short-Term Out-of-Pocket and Total Costs of Care After Ablation, Resection, or Transplant for Early-Stage Hepatocellular Carcinoma: A National SEER-Medicare Cost Comparison. American Journal Of Roentgenology 2024, 223: e2431272. PMID: 38899842, DOI: 10.2214/ajr.24.31272.Peer-Reviewed Original ResearchEarly-stage hepatocellular carcinomaHepatocellular carcinomaPost-procedure periodIndex procedureOut-of-pocket costsPatient out-of-pocket costsDrivers of high costsDays post-procedureSubgroup of patientsTreated with ablationPropensity-matched subgroupsU.S. population-based studyPopulation-based studySurgical resectionMultivariate linear regression modelSurgical treatmentPrognostic indicatorPost-procedureTreatment modalitiesTreatment optionsSEER-MedicareResectionMultivariate analysisTransplantationPropensity-scoreImage-guided percutaneous strategies to improve the resectability of HCC: Portal vein embolization, liver venous deprivation, or radiation lobectomy?
Chan S, Cornman-Homonoff J, Lucatelli P, Madoff D. Image-guided percutaneous strategies to improve the resectability of HCC: Portal vein embolization, liver venous deprivation, or radiation lobectomy? Clinical Imaging 2024, 111: 110185. PMID: 38781614, DOI: 10.1016/j.clinimag.2024.110185.Peer-Reviewed Original ResearchLiver venous deprivationPortal vein embolizationRadiation lobectomyVein embolizationResection of HCCMinimally invasive techniquesStandard of careHepatic malignanciesLiver remnantLiver insufficiencySurgical candidacySurgical techniqueHepatocellular carcinomaInvasive techniquesHepatic functionPercutaneous strategiesResectionPatient's likelihoodLobectomyEmbolizationLiverPatientsFLRCarcinomaMalignancy
2020
Improving the Safety of Major Resection for Hepatobiliary Malignancy: Portal Vein Embolization and Recent Innovations in Liver Regeneration Strategies
Madoff DC, Odisio BC, Schadde E, Gaba RC, Bennink RJ, van Gulik TM, Guiu B. Improving the Safety of Major Resection for Hepatobiliary Malignancy: Portal Vein Embolization and Recent Innovations in Liver Regeneration Strategies. Current Oncology Reports 2020, 22: 59. PMID: 32415401, DOI: 10.1007/s11912-020-00922-x.Peer-Reviewed Original ResearchConceptsPortal vein embolizationFuture liver remnantFLR hypertrophyMajor hepatectomyVein embolizationHepatobiliary malignanciesCT volumetryAppropriate surgical candidatesExtent of resectionPortal vein ligationRadiation lobectomyVenous deprivationMajor resectionPerformance statusSurgical candidatesComplication rateLiver diseaseVein ligationLiver partitionLiver remnantTumor typesPhysiological imagingResectionEmbolizationMalignancy
2019
Applications of transcatheter embolotherapy in preparation for liver transplantation and resection
Lin EY, Cornman-Homonoff J, Odisio BC, Madoff DC. Applications of transcatheter embolotherapy in preparation for liver transplantation and resection. Chinese Clinical Oncology 2019, 8: 59. PMID: 31865716, DOI: 10.21037/cco.2019.12.03.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsConceptsLocoregional therapyPost-resection outcomesLiver-directed therapiesAppropriate patient selectionEarly-stage diseasePre-operative periodMaximal potential benefitTranscatheter embolotherapyLiver transplantationPatient selectionSurgical interventionInterventional radiologyPartial hepatectomyTransplantationTherapyPotential benefitsResectionPatientsSurgeryEmbolotherapyHepatectomyDisease
2013
Interventional Radiology in the Multidisciplinary Management of Liver Lesions: Pre- and Postoperative Roles
Ward T, Madoff D, Weintraub J. Interventional Radiology in the Multidisciplinary Management of Liver Lesions: Pre- and Postoperative Roles. Seminars In Liver Disease 2013, 33: 213-225. PMID: 23943102, DOI: 10.1055/s-0033-1351778.Peer-Reviewed Original ResearchConceptsLocoregional therapyHepatobiliary surgeonsPostoperative roleInterventional radiologistsLiver lesionsColorectal cancer metastasisExternal beam radiationMultiple treatment modalitiesNontransplant candidatesTransplant criteriaVascular complicationsPostoperative settingMultidisciplinary managementTreatment modalitiesPreoperative roleComplex careInterventional radiologyRadiation oncologistsCancer metastasisPatientsMultidisciplinary approachResectionTransplantationOncologistsLesionsUpdate on Portal Vein Embolization: Evidence-based Outcomes, Controversies, and Novel Strategies
May BJ, Talenfeld AD, Madoff DC. Update on Portal Vein Embolization: Evidence-based Outcomes, Controversies, and Novel Strategies. Journal Of Vascular And Interventional Radiology 2013, 24: 241-254. PMID: 23369559, DOI: 10.1016/j.jvir.2012.10.017.Peer-Reviewed Original ResearchConceptsPortal vein embolizationFuture liver remnantVein embolizationCurative hepatic resectionPortal blood flowNumber of patientsTumor-bearing liverRecent outcome dataEvidence-based outcomesPostoperative morbidityFLR hypertrophyHepatic resectionLiver remnantPatient outcomesBlood flowOutcome dataNovel strategyEmbolizationSurgeryTherapyOutcomesMorbidityResectionPatientsHypertrophy
2012
Portal Vein Embolization: Rationale, Technique, and Current Application
May B, Madoff D. Portal Vein Embolization: Rationale, Technique, and Current Application. Seminars In Interventional Radiology 2012, 29: 081-089. PMID: 23729977, PMCID: PMC3444878, DOI: 10.1055/s-0032-1312568.Peer-Reviewed Original ResearchPortal vein embolizationFuture liver remnantPreoperative portal vein embolizationCurative-intent resectionComplicated postoperative courseNumber of patientsPostoperative morbidityHepatic resectionPostoperative courseVein embolizationSurgical outcomesLiver remnantPortal bloodLiver segmentsResectionTherapyCurrent useTechnical considerationsEmbolizationMorbidityPatientsSurgeryHypertrophyBlood
2011
The Ipsilateral Approach for Right PVE with or Without Segment 4
Madoff D. The Ipsilateral Approach for Right PVE with or Without Segment 4. 2011, 151-158. DOI: 10.1007/978-1-84882-122-4_17.Peer-Reviewed Original ResearchPortal vein embolizationFuture liver remnantIpsilateral approachSmall future liver remnantRight portal vein embolizationContralateral liver hypertrophyMajor liver resectionStandard of careMajor hepatectomyLiver resectionVein embolizationSubsequent resectionLiver remnantLiver hypertrophyPortal systemResectionSegment 4Operator preferenceEmbolizationPatientsHypertrophyHepatectomyLiverCareHigh Survival Rate After Two-Stage Resection of Advanced Colorectal Liver Metastases: Response-Based Selection and Complete Resection Define Outcome
Brouquet A, Abdalla EK, Kopetz S, Garrett CR, Overman MJ, Eng C, Andreou A, Loyer EM, Madoff DC, Curley SA, Vauthey JN. High Survival Rate After Two-Stage Resection of Advanced Colorectal Liver Metastases: Response-Based Selection and Complete Resection Define Outcome. Journal Of Clinical Oncology 2011, 29: 1083-1090. PMID: 21263087, PMCID: PMC3068054, DOI: 10.1200/jco.2010.32.6132.Peer-Reviewed Original ResearchMeSH KeywordsAdultAgedAntineoplastic AgentsChemotherapy, AdjuvantColorectal NeoplasmsFemaleHepatectomyHumansKaplan-Meier EstimateLiver NeoplasmsMaleMiddle AgedNeoadjuvant TherapyPatient SelectionRetrospective StudiesRisk AssessmentRisk FactorsSurvival RateTexasTime FactorsTomography, X-Ray ComputedTreatment OutcomeConceptsAdvanced colorectal liver metastasesTwo-stage resectionColorectal liver metastasesLiver metastasesComplete resectionSurvival rateMedical groupMajor postoperative complicationsSurvival of patientsChemotherapy initiationNonsurgical patientsOnly chemotherapyPostoperative complicationsColorectal metastasesMetastatic diseaseObjective responseWorse survivalTreat analysisGood respondersExcellent outcomesTSR groupInclusion criteriaResectionPatientsChemotherapy
2010
Portal Vein Embolization Prior to Resection
Madoff D, Avritscher R. Portal Vein Embolization Prior to Resection. 2010, 153-183. DOI: 10.1007/978-1-60327-522-4_11.Peer-Reviewed Original ResearchFuture liver remnantFunctional liver massHepatic failureLiver massNormal underlying liverExtended hospital stayMajor hepatic resectionChronic liver diseasePortal vein embolizationMajor technical complicationsFatal hepatic failureImportant risk factorPerioperative failureHospital stayHepatic resectionVein embolizationPerioperative careLiver diseaseUnderlying liverLiver remnantFluid retentionHepatobiliary neoplasiaRisk factorsHigh riskResection
2008
Is embolization of segment 4 portal veins before extended right hepatectomy justified?
Kishi Y, Madoff DC, Abdalla EK, Palavecino M, Ribero D, Chun YS, Vauthey JN. Is embolization of segment 4 portal veins before extended right hepatectomy justified? Surgery 2008, 144: 744-751. PMID: 19081016, PMCID: PMC5901738, DOI: 10.1016/j.surg.2008.05.015.Peer-Reviewed Original ResearchConceptsPreoperative portal vein embolizationPortal vein embolizationPortal veinHypertrophy rateVein embolizationRight portal vein embolizationExtended right hepatectomyLiver remnant volumeMajor hepatectomyRight hepatectomyCurative hepatectomySubsequent resectionClinical outcomesRemnant volumeEmbolizationComplicationsPatientsAbsolute increaseHepatectomyUninjured liverSignificant differencesVeinSegment 2Volume gainResectionStrategies for Resection Using Portal Vein Embolization: Metastatic Liver Cancer
de Baere T, Madoff D, de Baere T, Elias D, Goere D, Kohneh-Sahrhi N. Strategies for Resection Using Portal Vein Embolization: Metastatic Liver Cancer. Seminars In Interventional Radiology 2008, 25: 123-131. PMID: 21326553, PMCID: PMC3036476, DOI: 10.1055/s-2008-1076680.Peer-Reviewed Original ResearchPortal vein embolizationFuture remnant liverMetastatic liver cancerLiver metastasesVein embolizationLiver cancerUse of PVEMultiple bilateral liver metastasesBilateral liver metastasesVolume of parenchymaPostoperative morbidityLiver resectionOncological conceptLiver hypertrophyRemnant liverPreoperative hypertrophyIndividual patientsTherapeutic strategiesFunctional assessmentResectionOncological landscapeThermal ablationEmbolizationPatientsMetastasis
2007
Portal vein embolization before major hepatectomy and its effects on regeneration, resectability and outcome
Ribero D, Abdalla EK, Madoff DC, Donadon M, Loyer EM, Vauthey J. Portal vein embolization before major hepatectomy and its effects on regeneration, resectability and outcome. British Journal Of Surgery 2007, 94: 1386-1394. PMID: 17583900, DOI: 10.1002/bjs.5836.Peer-Reviewed Original ResearchConceptsPortal vein embolizationHepatic dysfunctionStandardized FLRVein embolizationMortality rateFuture liver remnant volumePostoperative hepatic dysfunctionLiver-related complicationsLiver remnant volumeDegree of hypertrophyHospital stayMajor hepatectomyPostoperative complicationsHepatic resectionLiver resectionRemnant volumePrognostic informationPatientsComplicationsDysfunctionVolumetric evaluationResectionEmbolizationOutcomesCent
2005
Portal Vein Embolization in Preparation for Major Hepatic Resection: Evolution of a New Standard of Care
Madoff DC, Abdalla EK, Vauthey JN. Portal Vein Embolization in Preparation for Major Hepatic Resection: Evolution of a New Standard of Care. Journal Of Vascular And Interventional Radiology 2005, 16: 779-790. PMID: 15947041, DOI: 10.1097/01.rvi.0000159543.28222.73.Peer-Reviewed Original ResearchConceptsPortal vein embolizationMajor hepatic resectionHepatic resectionVein embolizationFunctional hepatic reserveChronic liver diseasePortal blood flowNondiseased portionHospital stayHepatic reservePreoperative managementLiver diseaseLiver volumeBlood flowEmbolic agentResectionLiver regenerationMultidisciplinary approachEmbolizationPatientsLiverImaging techniquesComplex casesContraindicationsComplications