2023
Gastric cancer after Bariatric Bypass Surgery. Do they relate? (A Systematic Review)
Doukas S, Doukas P, Vageli D, Broder A. Gastric cancer after Bariatric Bypass Surgery. Do they relate? (A Systematic Review). Obesity Surgery 2023, 33: 1876-1888. PMID: 37041375, DOI: 10.1007/s11695-023-06567-6.Peer-Reviewed Original ResearchConceptsBariatric bypass surgeryBypass surgeryGastric cancerGastric cancer risk assessmentGastric bypass surgeryH. pylori infectionGastric cancer surveillanceCancer-promoting factorGastric cancer casesCancer risk assessmentBile refluxMorbid obesityTobacco smokingPylori infectionCancer surveillanceRisk factorsCancer casesFamily historyEffective treatmentSurgeryAdvanced stageSystematic reviewCancerFurther investigationObesity
2020
The Progressive Mutagenic Effects of Acidic Bile Refluxate in Hypopharyngeal Squamous Cell Carcinogenesis: New Insights
Sasaki CT, Doukas SG, Costa J, Vageli DP. The Progressive Mutagenic Effects of Acidic Bile Refluxate in Hypopharyngeal Squamous Cell Carcinogenesis: New Insights. Cancers 2020, 12: 1064. PMID: 32344873, PMCID: PMC7281001, DOI: 10.3390/cancers12051064.Peer-Reviewed Original ResearchAcidic bileUpper aerodigestive tractAdditional risk factorsBiomarkers of progressionSquamous cell carcinogenesisNF-κB activationNeck malignanciesAerodigestive tractInvasive cancerHistopathological changesRisk factorsHypopharyngeal mucosaEarly neoplasiaMalignant lesionsP53 expressionTranslational studiesVivo modelCell carcinogenesisBileExperimental modelEarly detectionCancerNovel evidenceMutagenic effectsFirst study