2023
Chemiexcitation: Mammalian Photochemistry in the Dark†
Brash D, Goncalves L. Chemiexcitation: Mammalian Photochemistry in the Dark†. Photochemistry And Photobiology 2023, 99: 251-276. PMID: 36681894, PMCID: PMC10065968, DOI: 10.1111/php.13781.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsConceptsExcited statesMammalian cellsCyclobutane pyrimidine dimersEvolutionary selectionBond rearrangementUnoccupied orbitalsGround stateReaction productsPyrimidine dimersChemiexcitationRecent findingsBiologyPathogenic eventsRadicalsUltraviolet lightMoleculesDrug-induced deafnessPotential pathogenesisCellsMelaninAchilles heelMammalsBiomoleculesPhotochemistryDNA
2020
Rethinking Causation for Data‐intensive Biology: Constraints, Cancellations, and Quantized Organisms
Brash DE. Rethinking Causation for Data‐intensive Biology: Constraints, Cancellations, and Quantized Organisms. BioEssays 2020, 42: e1900135. PMID: 32484248, PMCID: PMC7518294, DOI: 10.1002/bies.201900135.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsConceptsNew mathematical toolNew mathematical approachComputational toolsMathematical toolsData-intensive biologyMathematical approachNonlinear dependenciesOptimal stateQuantized statesSingle control pointPhysical hierarchyComplex organismsCausal propertiesOrganismsSignal cancellationControl pointsExperimental strategiesBiologyConstraintsPhysicsCancellationEccentricityRecent refinementsBiologistsBiological behavior
1978
Molecular Biology of Aging
Brash D, Hart R. Molecular Biology of Aging. 1978, 57-81. DOI: 10.1007/978-1-4613-3994-6_4.Chapters