2021
Joining Efforts for PTLD: Lessons Learned from Comparing the Approach and Treatment Strategies Across the Pediatric and Adult Age Spectra
Montanari F, Orjuela-Grimm M. Joining Efforts for PTLD: Lessons Learned from Comparing the Approach and Treatment Strategies Across the Pediatric and Adult Age Spectra. Current Hematologic Malignancy Reports 2021, 16: 52-60. PMID: 33544319, PMCID: PMC8117403, DOI: 10.1007/s11899-021-00606-8.Peer-Reviewed Original ResearchMeSH KeywordsAdultAntineoplastic Agents, ImmunologicalBone Marrow TransplantationChildHumansImmunotherapyImmunotherapy, AdoptiveLymphoproliferative DisordersRituximabStem Cell TransplantationConceptsAdult age spectrumCombination of immunochemotherapyRecent FindingsClinical trialsRisk-stratified strategiesTreatment-related toxicityLarge prospective studiesFuture therapeutic approachesNovel therapeutic strategiesNovel target therapiesLymphoproliferative disordersPediatric populationProspective studyRetrospective studyClinical algorithmTreatment paradigmTreatment strategiesTherapeutic approachesTherapeutic strategiesCellular therapyHeterogeneous groupPTLDTherapyDiseaseImmunochemotherapy
2016
Post‐transplant lymphoproliferative disorder: a heterogeneous conundrum – response to Weisenburger DD & Gross TG
Radeski D, Montanari F, Alobeid B, O'Connor OA, Bhagat G. Post‐transplant lymphoproliferative disorder: a heterogeneous conundrum – response to Weisenburger DD & Gross TG. British Journal Of Haematology 2016, 179: 856-857. PMID: 27471184, DOI: 10.1111/bjh.14272.Peer-Reviewed Original Research
2015
Recursive partitioning analysis of prognostic factors in post‐transplant lymphoproliferative disorders (PTLD): a 120 case single institution series
Montanari F, Radeski D, Seshan V, Alobeid B, Bhagat G, O'Connor OA. Recursive partitioning analysis of prognostic factors in post‐transplant lymphoproliferative disorders (PTLD): a 120 case single institution series. British Journal Of Haematology 2015, 171: 491-500. PMID: 26250758, DOI: 10.1111/bjh.13621.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultAgedChildChild, PreschoolCombined Modality TherapyEpstein-Barr Virus InfectionsFemaleHumansImmunosuppressive AgentsInfantLymphoproliferative DisordersMaleMiddle AgedMultivariate AnalysisOrgan TransplantationPostoperative ComplicationsPrognosisRisk AssessmentRituximabSeverity of Illness IndexYoung AdultConceptsPost-transplant lymphoproliferative disorderECOG scoreElderly patientsPediatric patientsLymphoproliferative disordersEastern Cooperative Oncology Group scoreECOG score 0Setting of immunosuppressionDecade of diagnosisNew prognostic scoreSingle-institution seriesHigh-risk groupAdult patientsOverall survivalPrognostic factorsPrognostic scoreInstitution seriesSingle institutionScore 0Tissue allograftsPatientsLarge seriesRisk categoriesHeterogeneous groupRecursive partitioning model
2010
Monomorphic T-cell post-transplant lymphoproliferative disorders exhibit markedly inferior outcomes compared to monomorphic B-cell post-transplant lymphoproliferative disorders
Montanari F, Bhagat G, Clark-Garvey S, Seshan V, Zain J, Diefenbach C, Mccormick E, Crook M, Conroy M, O'connor OA. Monomorphic T-cell post-transplant lymphoproliferative disorders exhibit markedly inferior outcomes compared to monomorphic B-cell post-transplant lymphoproliferative disorders. Leukemia & Lymphoma 2010, 51: 1761-1764. PMID: 20807097, DOI: 10.3109/10428194.2010.500436.Peer-Reviewed Original ResearchMeSH KeywordsAdultAgedB-LymphocytesFemaleHumansLymphoproliferative DisordersMaleMiddle AgedOrgan TransplantationPostoperative ComplicationsSurvival RateT-LymphocytesTreatment OutcomeBone marrow involvement in patients with posttransplant lymphoproliferative disorders: incidence and prognostic factors
Montanari F, O'Connor OA, Savage DG, Zain JM, Venkatraman S, McCormick EK, Crook MT, Tsao L, Sevilla DW, Bhagat G, Alobeid B. Bone marrow involvement in patients with posttransplant lymphoproliferative disorders: incidence and prognostic factors. Human Pathology 2010, 41: 1150-1158. PMID: 20381113, DOI: 10.1016/j.humpath.2009.11.016.Peer-Reviewed Original ResearchConceptsMonomorphic posttransplant lymphoproliferative disorderPosttransplant lymphoproliferative disorderBone marrow involvementPolymorphic posttransplant lymphoproliferative disordersDiffuse large B-cell lymphomaLarge B-cell lymphomaMarrow involvementLymphoproliferative disordersB-cell lymphomaSerologic parametersEpstein-Barr virus statusPosttransplant lymphoproliferative disorder patientsDe novo diffuse large B-cell lymphomaNovo diffuse large B-cell lymphomaBone marrow examinationElevated lactate dehydrogenaseBone marrow biopsyHodgkin lymphoma typeDiffuse large B-cell lymphoma casesLarge B-cell lymphoma casesB-cell lymphoma casesSensitive screening toolStaging biopsiesExtranodal involvementMarrow examination