2024
The International Association for the Study of Lung Cancer Lung Cancer Staging Project: Proposals for Revision of the TNM Stage Groups in the Forthcoming (Ninth) Edition of the TNM Classification for Lung Cancer
Rami-Porta R, Nishimura K, Giroux D, Detterbeck F, Cardillo G, Edwards J, Fong K, Giuliani M, Huang J, Kernstine K, Marom E, Nicholson A, Van Schil P, Travis W, Tsao M, Watanabe S, Rusch V, Asamura H, Boards A. The International Association for the Study of Lung Cancer Lung Cancer Staging Project: Proposals for Revision of the TNM Stage Groups in the Forthcoming (Ninth) Edition of the TNM Classification for Lung Cancer. Journal Of Thoracic Oncology 2024, 19: 1007-1027. PMID: 38447919, DOI: 10.1016/j.jtho.2024.02.011.Peer-Reviewed Original ResearchClassification of lung cancerLung cancerTNM classificationStage groupSignificance of survival differencesInternational Association for the Study of Lung CancerLung Cancer Staging ProjectTNM stage groupingTNM classification of lung cancerStudy of Lung CancerEdition TNMStage NSCLCPathological stageClinical stageSurvival differencesAnatomic extentTNMSurvival analysisTreatment approachesCancerStatistical significanceMultivariate regressionPatientsLung
2019
Quality Versus Quantity
Chiu AS, Arnold BN, Hoag JR, Herrin J, Kim CH, Salazar MC, Monsalve AF, Jean RA, Blasberg JD, Detterbeck FC, Gross CP, Boffa DJ. Quality Versus Quantity. Annals Of Surgery 2019, Publish Ahead of Print: &na;. PMID: 29697446, DOI: 10.1097/sla.0000000000002762.Peer-Reviewed Original ResearchConceptsComplex cancer surgeryCancer surgerySafe hospitalComplex oncologic surgeryPotential mortality reductionNational Cancer DatabaseHigh-volume hospitalsHospital quality measuresSurgical mortalityPrimary cancerHospital rating systemsOncologic surgeryCancer DatabaseMortality reductionSurgical volumeHospital safetyPatient realignmentPatientsHospitalSurgeryMeaningful reductionPublic reportingMortalityRSMRCancer
2018
Eighth Edition Staging of Thoracic Malignancies: Implications for the Reporting Pathologist
Nicholson AG, Tsao MS, Travis WD, Patil DT, Galateau-Salle F, Marino M, Dacic S, Beasley MB, Butnor KJ, Yatabe Y, Pass HI, Rusch VW, Detterbeck FC, Asamura H, Rice TW, Rami-Porta R. Eighth Edition Staging of Thoracic Malignancies: Implications for the Reporting Pathologist. Archives Of Pathology & Laboratory Medicine 2018, 142: 645-661. PMID: 29480761, DOI: 10.5858/arpa.2017-0245-ra.Peer-Reviewed Original ResearchConceptsAmerican Joint CommitteeInternational Cancer ControlThoracic malignanciesReporting pathologistCancer controlJoint CommitteeWorldwide Esophageal Cancer CollaborationInternational Thymic Malignancy Interest GroupUS National Cancer DatabaseInternational Mesothelioma Interest GroupEighth edition stagingNational Cancer DatabaseThymic epithelial tumorsPrognostic Factors CommitteeEdition stagingStaging ManualEsophagogastric junctionThoracic cancerLung cancerCancer DatabaseRespective tumorsEpithelial tumorsEpithelial cancersCancerStagingPeeling back the onion: addressing nuances of CT screening for lung cancer
Detterbeck FC. Peeling back the onion: addressing nuances of CT screening for lung cancer. Journal Of Thoracic Disease 2018, 10: 585-588. PMID: 29608192, PMCID: PMC5864623, DOI: 10.21037/jtd.2018.01.73.Peer-Reviewed Original Research
2017
Effectiveness of local therapy for stage I non–small-cell lung cancer in nonagenarians
Arnold BN, Thomas DC, Rosen JE, Salazar MC, Detterbeck FC, Blasberg JD, Boffa DJ, Kim AW. Effectiveness of local therapy for stage I non–small-cell lung cancer in nonagenarians. Surgery 2017, 162: 640-651. PMID: 28697883, DOI: 10.1016/j.surg.2017.04.025.Peer-Reviewed Original ResearchMeSH KeywordsAged, 80 and overCarcinoma, Non-Small-Cell LungConfidence IntervalsDatabases, FactualDisease-Free SurvivalFemaleGeriatric AssessmentHumansKaplan-Meier EstimateLogistic ModelsLung NeoplasmsMaleMultivariate AnalysisNeoplasm InvasivenessNeoplasm StagingOdds RatioPneumonectomyProportional Hazards ModelsRadiotherapyRegistriesRisk AssessmentSecondary PreventionSurvival AnalysisConceptsCell lung cancerLocal therapyLung cancerStage IRelative survivalStereotactic body radiation therapyNational Cancer DatabaseBetter overall survivalBody radiation therapyOlder patientsOverall survivalPatient ageYounger patientsOverall mortalityPrimary outcomeCancer DatabaseTreatment outcomesTreatment decisionsRadiation therapyPatientsTherapyCancerNonagenariansTreatmentSurvivalScientific Advances in Thoracic Oncology 2016
Soo RA, Stone ECA, Cummings KM, Jett JR, Field JK, Groen HJM, Mulshine JL, Yatabe Y, Bubendorf L, Dacic S, Rami-Porta R, Detterbeck FC, Lim E, Asamura H, Donington J, Wakelee HA, Wu YL, Higgins K, Senan S, Solomon B, Kim DW, Johnson M, Yang JCH, Sequist LV, Shaw AT, Ahn MJ, Costa DB, Patel JD, Horn L, Gettinger S, Peters S, Wynes MW, Faivre-Finn C, Rudin CM, Tsao A, Baas P, Kelly RJ, Leighl NB, Scagliotti GV, Gandara DR, Hirsch FR, Spigel DR. Scientific Advances in Thoracic Oncology 2016. Journal Of Thoracic Oncology 2017, 12: 1183-1209. PMID: 28579481, DOI: 10.1016/j.jtho.2017.05.019.Peer-Reviewed Original ResearchConceptsLung cancer careLung cancer researchValue of careAdjuvant therapyThoracic cancerCancer careLung cancerThoracic oncologyCare provideEarly detectionKinase inhibitorsGenomic testingImmunotherapyTherapyCancerCancer researchCareMultiple areasMolecular diagnosticsAnnual updateConcise reviewNSCLCInternational AssociationSurgeryMesothelioma“What if I do nothing?” The natural history of operable cancer of the alimentary tract
Keshava HB, Rosen JE, DeLuzio MR, Kim AW, Detterbeck FC, Boffa DJ. “What if I do nothing?” The natural history of operable cancer of the alimentary tract. European Journal Of Surgical Oncology 2017, 43: 788-795. PMID: 28131669, DOI: 10.1016/j.ejso.2016.12.006.Peer-Reviewed Original ResearchMeSH KeywordsAdenocarcinomaAdultAgedAged, 80 and overCarcinoma, Signet Ring CellCarcinoma, Squamous CellColonic NeoplasmsDatabases, FactualDisease ProgressionEsophageal NeoplasmsFemaleGastrointestinal NeoplasmsHumansMaleMiddle AgedNeoplasm StagingRectal NeoplasmsStomach NeoplasmsSurvival RateUnited StatesWatchful WaitingConceptsAlimentary tract cancersTract cancerNatural historyUntreated patientsCancer surgeryClinical stage IStage-specific survivalOperable cancerInoperable patientsMedian survivalRectal cancerClinical stagePreoperative counselingPatientsStage ISurgeryCancerPoor healthAlimentary tractSurvivalHealth reasonsStudy objectiveTreatmentCIICIII
2016
The Eighth Edition Lung Cancer Stage Classification
Detterbeck FC, Boffa DJ, Kim AW, Tanoue LT. The Eighth Edition Lung Cancer Stage Classification. CHEST Journal 2016, 151: 193-203. PMID: 27780786, DOI: 10.1016/j.chest.2016.10.010.Peer-Reviewed Original ResearchConceptsLung cancer stage classificationCancer stage classificationCohort of patientsAnatomic extentContemporary patientsLung cancerClinical studiesStage classificationEighth editionSpecific patientPatientsInternal validationCancerStage classification systemMultiple assessmentsClassification systemCohortCliniciansThe IASLC Lung Cancer Staging Project: Methodology and Validation Used in the Development of Proposals for Revision of the Stage Classification of NSCLC in the Forthcoming (Eighth) Edition of the TNM Classification of Lung Cancer
Detterbeck FC, Chansky K, Groome P, Bolejack V, Crowley J, Shemanski L, Kennedy C, Krasnik M, Peake M, Rami-Porta R, Goldstraw P, Rami-Porta R, Asamura H, Ball D, Beer D, Beyruti R, Bolejack V, Chansky K, Crowley J, Detterbeck F, Eberhardt W, Edwards J, Galateau-Sallé F, Giroux D, Gleeson F, Groome P, Huang J, Kennedy C, Kim J, Kim Y, Kingsbury L, Kondo H, Krasnik M, Kubota K, Lerut A, Lyons G, Marino M, Marom E, van Meerbeeck J, Mitchell A, Nakano T, Nicholson A, Nowak A, Peake M, Rice T, Rosenzweig K, Ruffini E, Rusch V, Saijo N, Van Schil P, Sculier J, Shemanski L, Stratton K, Suzuki K, Tachimori Y, Thomas C, Travis W, Tsao M, Turrisi A, Vansteenkiste J, Watanabe H, Wu Y, Baas P, Erasmus J, Hasegawa S, Inai K, Kernstine K, Kindler H, Krug L, Nackaerts K, Pass H, Rice D, Falkson C, Filosso P, Giaccone G, Kondo K, Lucchi M, Okumura M, Blackstone E, Cavaco F, Barrera E, Arca J, Lamelas I, Obrer A, Jorge R, Ball D, Bascom G, Orozco A, Castro M, Blum M, Chimondeguy D, Cvijanovic V, Defranchi S, de Olaiz Navarro B, Campuzano I, Vidueira I, Araujo E, García F, Fong K, Corral G, González S, Gilart J, Arangüena L, Barajas S, Girard P, Goksel T, Budiño M, Casaurrán G, Blanco J, Hernández J, Rodríguez H, Collantes J, Heras M, Elena J, Jakobsen E, Kostas S, Atance P, Ares A, Liao M, Losanovscky M, Lyons G, Magaroles R, De Esteban Júlvez L, Gorospe M, McCaughan B, Kennedy C, Íñiguez R, Sorribes L, Gozalo S, de Arriba C, Delgado M, Alarcón J, Cuesta J, Park J, Pass H, Fernández M, Rosenberg M, Ruffini E, Rusch V, de Cos Escuín J, Vinuesa A, Mitjans M, Strand T, Subotic D, Swisher S, Terra R, Thomas C, Tournoy K, Van Schil P, Velasquez M, Wu Y, Yokoi K, Rami-Porta R, Ball D, Bolejack V, Crowley J, Giroux D, Kim J, Lyons G, Rice T, Suzuki K, Thomas C, Travis W, Wu Y, Asamura H, Ball D, Chansky K, Crowley J, Goldstraw P, Rusch V, van Schil P, Vansteenkiste J, Watanabe H, Wu Y, Zielinski M, Eberhardt W, Chansky K, Crowley J, Kim Y, Kondo H, Mitchell A, Turrisi A, Groome P, Detterbeck F, Bolejack V, Crowley J, Kennedy C, Krasnik M, Peake M, Sculier J, Chansky K, Crowley J, Giroux D, Gleeson F, van Meeerbeeck J, Travis W, Asamura H, Chansky K, Crowley J, Giroux D, Nicholson A, Beyruti R, Chansky K, Crowley J, Kubota K, Turrisi A, Tsao M, Beer D, Crowley J, Wu Y, Travis W, Asamura H, Bankier A, Beasley M, Detterbeck F, Flieder D, Goo J, MacMahon H, Naidich D, Nicholson A, Powell C, Prokop M, Rami-Porta R, Rusch V, van Schil P, Yatabe Y, Detterbeck F, Arenberg D, Asamura H, Bolejack V, Crowley J, Donington J, Franklin W, Girard N, Marom E, Mazzone P, Nicholson A, Rusch V, Tanoue L, Travis W. The IASLC Lung Cancer Staging Project: Methodology and Validation Used in the Development of Proposals for Revision of the Stage Classification of NSCLC in the Forthcoming (Eighth) Edition of the TNM Classification of Lung Cancer. Journal Of Thoracic Oncology 2016, 11: 1433-1446. PMID: 27448762, DOI: 10.1016/j.jtho.2016.06.028.Peer-Reviewed Original ResearchConceptsLung cancerLung cancer stage classificationIASLC Lung Cancer Staging ProjectLung Cancer Staging ProjectDifferent patient cohortsCancer stage classificationPrognostic Factors CommitteeAnatomic extentHistologic typeTNM classificationDefinition of tumorMetastasis classificationPatient cohortMetastasis categoryStage groupingEnough patientsStage classificationEighth editionCancerPatientsDiscriminatory abilityExternal validationTumorsInternational databasesEvidence of applicabilityLung Cancer in the Very Young: Treatment and Survival in the National Cancer Data Base
Arnold BN, Thomas DC, Rosen JE, Salazar MC, Blasberg JD, Boffa DJ, Detterbeck FC, Kim AW. Lung Cancer in the Very Young: Treatment and Survival in the National Cancer Data Base. Journal Of Thoracic Oncology 2016, 11: 1121-1131. PMID: 27103511, DOI: 10.1016/j.jtho.2016.03.023.Peer-Reviewed Original ResearchConceptsNon-small cell lung cancerNational Cancer Data BaseYounger patientsOlder patientsLung cancerRelative survivalStage IAdvanced stage non-small cell lung cancerCell lung cancerYears of ageAggressive therapyAggressive treatmentOverall survivalPatient demographicsPrimary outcomeTreatment patternsTumor characteristicsNSCLC casesPatientsStage IIIDetailed stagingSurvival informationOlder groupDistinct subsetsCancerThe IASLC Lung Cancer Staging Project: Background Data and Proposals for the Classification of Lung Cancer with Separate Tumor Nodules in the Forthcoming Eighth Edition of the TNM Classification for Lung Cancer
Detterbeck FC, Bolejack V, Arenberg DA, Crowley J, Donington JS, Franklin WA, Girard N, Marom EM, Mazzone PJ, Nicholson AG, Rusch VW, Tanoue LT, Travis WD, Asamura H, Rami-Porta R, Committee I, Goldstraw P, Rami-Porta R, Asamura H, Ball D, Beer D, Beyruti R, Bolejack V, Chansky K, Crowley J, Detterbeck F, Eberhardt W, Edwards J, Galateau-Sallé F, Giroux D, Gleeson F, Groome P, Huang J, Kennedy C, Kim J, Kim Y, Kingsbury L, Kondo H, Krasnik M, Kubota K, Lerut A, Lyons G, Marino M, Marom E, van Meerbeeck J, Mitchell A, Nakano T, Nicholson A, Nowak A, Peake M, Rice T, Rosenzweig K, Ruffini E, Rusch V, Saijo N, Van Schil P, Sculier J, Shemanski L, Stratton K, Suzuki K, Tachimori Y, Thomas C, Travis W, Tsao M, Turrisi A, Vansteenkiste J, Watanabe H, Wu Y, Boards A, Baas P, Erasmus J, Hasegawa S, Inai K, Kernstine K, Kindler H, Krug L, Nackaerts K, Pass H, Rice D, Falkson C, Filosso P, Giaccone G, Kondo K, Lucchi M, Okumura M, Blackstone E, Workgroup M, Flieder D, Godoy M, Goo J, Goodman L, Jett J, de Leyn P, Marchevsky A, MacMahon H, Naidich D, Okada M, Perlman M, Powell C, van Schil P, Warth A, Institutions P, Cavaco F, Barrera E, Arca J, Lamelas I, Obrer A, Jorge R, Ball D, Bascom G, Orozco A, Castro M, Blum M, Chimondeguy D, Cvijanovic V, Defranchi S, de Olaiz Navarro B, Campuzano I, Vidueira I, Araujo E, García F, Fong K, Corral G, González S, Gilart J, Arangüena L, Barajas S, Girard P, Goksel T, Budiño M, Casaurrán G, Blanco J, Hernández J, Rodríguez H, Collantes J, Heras M, Elena J, Jakobsen E, Kostas S, Atance P, Ares A, Liao M, Losanovscky M, Lyons G, Magaroles R, De Esteban Júlvez L, Gorospe M, McCaughan B, Kennedy C, Íñiguez R, Sorribes L, Gozalo S, de Arriba C, Delgado M, Alarcón J, Cuesta J, Park J, Pass H, Fernández M, Rosenberg M, Ruffini E, Rusch V, de Cos Escuín J, Vinuesa A, Mitjans M, Strand T, Subotic D, Swisher S, Terra R, Thomas C, Tournoy K, Van Schil P, Velasquez M, Wu Y, Yokoi K. The IASLC Lung Cancer Staging Project: Background Data and Proposals for the Classification of Lung Cancer with Separate Tumor Nodules in the Forthcoming Eighth Edition of the TNM Classification for Lung Cancer. Journal Of Thoracic Oncology 2016, 11: 681-692. PMID: 26940530, DOI: 10.1016/j.jtho.2015.12.114.Peer-Reviewed Original ResearchConceptsSeparate tumor nodulesPrimary lung cancerLung cancerTumor nodulesEighth editionTNM classificationSurvival differencesSecond primary lung cancerIASLC Lung Cancer Staging ProjectLung Cancer Staging ProjectForthcoming Eighth EditionSame histologic appearanceProportion of patientsSurvival of patientsLung cancer databaseT3 tumorsT4 tumorsIndex tumorCancer DatabaseSuch tumorsHistologic appearanceAnatomic classificationPatientsTumorsCancer
2015
What is quality, and can we define it in lung cancer?—the case for quality improvement
Farjah F, Detterbeck FC. What is quality, and can we define it in lung cancer?—the case for quality improvement. Translational Lung Cancer Research 2015, 4: 365-72. PMID: 26380177, PMCID: PMC4549465, DOI: 10.3978/j.issn.2218-6751.2015.07.12.Peer-Reviewed Original Research
2014
Quality Indicators for the Evaluation of Patients With Lung Cancer
Mazzone PJ, Vachani A, Chang A, Detterbeck F, Cooke D, Howington J, Dodi A, Arenberg D. Quality Indicators for the Evaluation of Patients With Lung Cancer. CHEST Journal 2014, 146: 659-669. PMID: 24700172, PMCID: PMC4694080, DOI: 10.1378/chest.13-2900.Peer-Reviewed Original ResearchConceptsThoracic Oncology NetworkStaging of patientsCare quality indicatorsLung cancerOncology NetworkPerformance status measuresEvaluation of patientsEvidence-based guidelinesLung cancer specialistsCare of patientsAcademic medical centerQuality improvement committeeCessation counselingChest PhysiciansCancer specialistsMedical CenterAmerican CollegeTissue acquisitionMolecular testingStatus measuresPatientsQuality indicatorsCancerStagingImprovement CommitteeClinical Presentation and Evaluation of Neuroendocrine Tumors of the Lung
Detterbeck FC. Clinical Presentation and Evaluation of Neuroendocrine Tumors of the Lung. Thoracic Surgery Clinics 2014, 24: 267-276. PMID: 25065927, DOI: 10.1016/j.thorsurg.2014.04.002.Peer-Reviewed Original ResearchConceptsCell lung cancerCarcinoid tumorsLung cancerNeuroendocrine tumorsLimited biopsyNon-small cell lung cancerLarge cell neuroendocrine cancerMost non-small cell lung cancersSmall cell lung cancerPeripheral parenchymal lesionAtypical carcinoid tumorTypical carcinoid tumorNode enlargementEndobronchial tumorMediastinal tumorCharacteristic presentationClinical presentationParenchymal lesionsNeuroendocrine cancerRapid progressionTumorsCancerBiopsyLungPresentationHow many names for a rose: Inconsistent classification of multiple foci of lung cancer due to ambiguous rules
Fonseca A, Detterbeck FC. How many names for a rose: Inconsistent classification of multiple foci of lung cancer due to ambiguous rules. Lung Cancer 2014, 85: 7-11. PMID: 24768582, DOI: 10.1016/j.lungcan.2014.02.014.Peer-Reviewed Original ResearchConceptsLung cancerPulmonary fociSeparate primary cancersOutcomes of patientsComparison of outcomesDifferent histologic typesMultifocal lung cancerSuch patientsHistologic typePrimary cancerPatient groupClinical scenariosPatientsCancerMultiple fociStage classificationMarked variabilityOutcomesInconsistent classificationClinicians
2013
The Stage Classification of Lung Cancer Diagnosis and Management of Lung Cancer, 3rd ed: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines
Detterbeck FC, Postmus PE, Tanoue LT. The Stage Classification of Lung Cancer Diagnosis and Management of Lung Cancer, 3rd ed: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines. CHEST Journal 2013, 143: e191s-e210s. PMID: 23649438, DOI: 10.1378/chest.12-2354.Peer-Reviewed Original ResearchConceptsChest Physicians Evidence-Based Clinical Practice GuidelinesEvidence-based clinical practice guidelinesClinical practice guidelinesLung cancer diagnosisLung cancerTNM descriptorsPractice guidelinesAmerican CollegeSeventh editionCancer diagnosisStage classification systemClassification systemStage classificationCancerDiagnosisExecutive Summary Diagnosis and Management of Lung Cancer, 3rd ed: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines
Detterbeck FC, Lewis SZ, Diekemper R, Addrizzo-Harris D, Alberts WM. Executive Summary Diagnosis and Management of Lung Cancer, 3rd ed: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines. CHEST Journal 2013, 143: 7s-37s. PMID: 23649434, DOI: 10.1378/chest.12-2377.Peer-Reviewed Original Research
2012
Counterpoint: Are Limited Resections Appropriate in Non-small Cell Lung Cancer? No Don't Overdo It, and Don't Get Confused
Detterbeck FC. Counterpoint: Are Limited Resections Appropriate in Non-small Cell Lung Cancer? No Don't Overdo It, and Don't Get Confused. CHEST Journal 2012, 141: 590-592. PMID: 22396559, DOI: 10.1378/chest.11-3110.Peer-Reviewed Original ResearchCurrent Status of Lung Cancer Screening
Ahmad U, Detterbeck FC. Current Status of Lung Cancer Screening. Seminars In Thoracic And Cardiovascular Surgery 2012, 24: 27-36. PMID: 22643659, DOI: 10.1053/j.semtcvs.2012.01.014.Peer-Reviewed Original Research
2011
Pushing Forward Into the Darkness, Leaping, and Landing Securely Prognostication and Adjuvant Chemotherapy for Lung Cancer
Detterbeck FC. Pushing Forward Into the Darkness, Leaping, and Landing Securely Prognostication and Adjuvant Chemotherapy for Lung Cancer. CHEST Journal 2011, 140: 1398-1400. PMID: 22147814, DOI: 10.1378/chest.11-1988.Peer-Reviewed Original Research