2001
PREVALENCE OF ANTIBODIES TO HUMAN HERPESVIRUS 8 (HHV-8) IN SAUDI ARABIAN PATIENTS WITH AND WITHOUT RENAL FAILURE1234
Almuneef M, Nimjee S, Khoshnood K, Miller G, Rigsby M. PREVALENCE OF ANTIBODIES TO HUMAN HERPESVIRUS 8 (HHV-8) IN SAUDI ARABIAN PATIENTS WITH AND WITHOUT RENAL FAILURE1234. Transplantation 2001, 71: 1120-1124. PMID: 11374413, DOI: 10.1097/00007890-200104270-00019.Peer-Reviewed Original ResearchConceptsEnd-stage renal diseasePosttransplantation Kaposi's sarcomaPrevalence of antibodiesKaposi's sarcomaHuman herpesvirus 8HHV-8Renal diseaseHerpesvirus 8High incidenceHHV-8-seropositive individualsSmall viral capsid antigenHHV-8 infectionRenal transplant recipientsViral capsid antigenComparison groupArea of residenceSeronegative subjectsESRD patientsSeropositive subjectsTransplant recipientsCapsid antigenSerologic evidenceSeropositive individualsCommon cancerPatients
2000
Genetically and epidemiologically related “non‐syncytium‐inducing” isolates of HIV‐1 display heterogeneous growth patterns in macrophages
Jesus M, Anders C, Miller G, Sleasman J, Goodenow M, Andiman W. Genetically and epidemiologically related “non‐syncytium‐inducing” isolates of HIV‐1 display heterogeneous growth patterns in macrophages. Journal Of Medical Virology 2000, 61: 171-180. PMID: 10797371, DOI: 10.1002/(sici)1096-9071(200006)61:2<171::aid-jmv1>3.0.co;2-x.Peer-Reviewed Original ResearchMeSH KeywordsAdultAmino Acid SequenceAntigens, ViralCD4 AntigensCell LineCells, CulturedChild, PreschoolFemaleGiant CellsHIV Core Protein p24HIV InfectionsHIV-1HumansInfantLeukocytes, MononuclearMacrophagesMolecular Sequence DataPhenotypeProspective StudiesProtein Structure, TertiaryReceptors, ChemokineTransfectionTropismU937 CellsViral ProteinsVirus ReplicationConceptsNSI virusesDisease stageSurrogate markerPediatric human immunodeficiency virus type 1 (HIV-1) infectionHuman immunodeficiency virus type 1 (HIV-1) infectionVirus type 1 infectionCell linesCo-receptor preferenceM-tropic virusesType 1 infectionT-cell tropicDual tropicInducing (NSI) virusesNSI isolatesAsymptomatic childrenMacrophage-tropicClinical progressionSymptomatic childrenV3 loopNSI phenotypeHIV-1Lymphotropic virusCategory A1Heterogeneous growth patternsGenetic features
1998
High Prevalence of Antibodies to Human Herpesvirus 8 in Relatives of Patients with Classic Kaposi's Sarcoma from Sardinia
Angeloni A, Heston L, Uccini S, Sirianni M, Cottoni F, Masala M, Cerimele D, Lin S, Sun R, Rigsby M, Faggioni A, Miller G. High Prevalence of Antibodies to Human Herpesvirus 8 in Relatives of Patients with Classic Kaposi's Sarcoma from Sardinia. The Journal Of Infectious Diseases 1998, 177: 1715-1718. PMID: 9607855, DOI: 10.1086/517429.Peer-Reviewed Original ResearchConceptsSmall viral capsid antigenPrevalence of antibodiesClassic Kaposi's sarcomaHigh incidence areaKaposi's sarcomaActive HHV-8 infectionHuman herpesvirus type 8HHV-8 infectionViral capsid antigenRelatives of patientsHuman herpesvirus 8Familial risk factorsCapsid antigenRisk factorsHigh prevalenceKS patientsHerpesvirus 8SarcomaIncidence areaPopulation agesPatientsVertical transmissionPrevalenceAntibodiesType 8SEROLOGIC ASSOCIATION OF HUMAN HERPESVIRUS EIGHT WITH POSTTRANSPLANT KAPOSI'S SARCOMA IN SAUDI ARABIA1
Wajeh Q, Othman A, Khalid A, Lin3 4, Ren S, Lee H, Ross5 6, Rigsby7 8, Miller3 5. SEROLOGIC ASSOCIATION OF HUMAN HERPESVIRUS EIGHT WITH POSTTRANSPLANT KAPOSI'S SARCOMA IN SAUDI ARABIA1. Transplantation 1998, 65: 583-585. PMID: 9500639, DOI: 10.1097/00007890-199802270-00024.Peer-Reviewed Original ResearchConceptsPosttransplant Kaposi's sarcomaRenal transplant patientsKaposi's sarcomaTransplant patientsSmall viral capsid antigenRenal transplant recipientsTertiary care hospitalViral capsid antigenCross-sectional studyHHV8 antigensSerologic associationsTransplant recipientsRenal failureCare hospitalCapsid antigenCommon cancerControl subjectsSaudi ArabiaSeroreactivity ratesKS patientsSerologic resultsControl groupControl individualsPatientsSarcoma
1997
The transcriptional activator Sp1, a novel autoantigen
Spain T, Sun R, Gradzka M, Lin S, Craft J, Miller G. The transcriptional activator Sp1, a novel autoantigen. Arthritis & Rheumatism 1997, 40: 1085-1095. PMID: 9182919, DOI: 10.1002/art.1780400613.Peer-Reviewed Original ResearchConceptsTranscriptional activator Sp1Novel autoantigenComplex of DNAGC-rich sequencesActivator Sp1Undifferentiated connective tissue diseaseSp1 proteinTranscription activatorConnective tissue diseaseExtractable nuclear antigensEpstein-Barr virusSp1Nuclear extractsCellular DNAMalar rashAntinuclear antibodiesClinical characteristicsProteinDNARaynaud's phenomenonTissue diseaseAutoantigenic proteinsAutoimmune seraElectrophoretic mobilityAutoantigens
1996
Antibodies to Butyrate-Inducible Antigens of Kaposi's Sarcoma–Associated Herpesvirus in Patients with HIV-1 Infection
Miller G, Rigsby M, Heston L, Grogan E, Sun R, Metroka C, Levy J, Gao S, Chang Y, Moore P. Antibodies to Butyrate-Inducible Antigens of Kaposi's Sarcoma–Associated Herpesvirus in Patients with HIV-1 Infection. New England Journal Of Medicine 1996, 334: 1292-1297. PMID: 8609946, DOI: 10.1056/nejm199605163342003.Peer-Reviewed Original ResearchConceptsHIV-1-infected patientsEpstein-Barr virusKaposi's sarcomaBC-1 cellsHuman immunodeficiency virus type 1 (HIV-1) infectionVirus type 1 infectionPositive serologic responseHIV-1 infectionType 1 infectionHigh-risk populationAntigen-positive cellsPresence of antibodiesPositive predictive valueEBV antigensKSHV antigensP40 antigenSerologic markersSerologic responseKaposi's Sarcoma-Associated HerpesvirusEtiologic roleSerologic testsPatientsSarcomaPredictive valueKSHV infection
1993
Quantitative leukoviremia and immune complex-dissociated antigenemia as predictors of infection status in children born to mothers infected with human immunodeficiency virus type 1
Ikeda M, Andiman W, Mezger J, Shapiro E, Miller G. Quantitative leukoviremia and immune complex-dissociated antigenemia as predictors of infection status in children born to mothers infected with human immunodeficiency virus type 1. The Journal Of Pediatrics 1993, 122: 524-531. PMID: 8463895, DOI: 10.1016/s0022-3476(05)83530-9.Peer-Reviewed Original ResearchConceptsHuman immunodeficiency virus type 1Immunodeficiency virus type 1Virus type 1Infection statusCulture resultsHIV-1-infected mothersType 1Peripheral blood mononuclear cellsSerum antigen testHIV-1 antigensBlood mononuclear cellsPositive culture resultsNegative culture resultsSeronegative donorsInfected childrenReactive antibodiesAntigen testMononuclear cellsClinical criteriaHIV-1Immune complexesCocultureChildrenPositive resultsAntigen
1992
Detection of Epstein‐Barr virus in the brain by the polymerase chain reaction
Pedneault L, Katz B, Miller G. Detection of Epstein‐Barr virus in the brain by the polymerase chain reaction. Annals Of Neurology 1992, 32: 184-192. PMID: 1324632, DOI: 10.1002/ana.410320210.Peer-Reviewed Original ResearchConceptsEpstein-Barr virusEBV DNAPolymerase chain reactionRole of EBVChain reactionCentral nervous system syndromeDiverse neurological syndromesKidney transplant recipientsHerpes group virusesTransplant recipientsMetabolic encephalopathiesBrain biopsyImmunodeficiency syndromeNeurological syndromeImmunodeficient hostsEBV genomeBrain specimensViral isolationPatientsGroup virusesSerological testsSyndromeBrainVirusEncephalitis
1991
Relation between HIV-1 syncytium inhibition antibodies and clinical outcome in children
Brenner TJ, Dahl KE, Miller G, Andiman W, Andiman WA, Olson B, Miller G, Andiman W, Miller G. Relation between HIV-1 syncytium inhibition antibodies and clinical outcome in children. The Lancet 1991, 337: 1001-1005. PMID: 1673167, DOI: 10.1016/0140-6736(91)92660-t.Peer-Reviewed Original ResearchConceptsLymphocytic interstitial pneumonitisOpportunistic infectionsClinical outcomesSyncytium formationCD4 receptorHIV-1-infected mothersWestern blotHIV-1 infected cellsInterstitial pneumonitisInhibition antibodiesHIV-1Giant cellsIndicator cellsAntibodiesInfected cellsTitresChildrenCell linesCell spreadSerumReceptorsOutcomesVirusCellsPneumonitis
1984
Regions of the EBV genome involved in latency and lymphocyte immortalization.
Miller G. Regions of the EBV genome involved in latency and lymphocyte immortalization. Medical Virology 1984, 30: 107-28. PMID: 6087408.Peer-Reviewed Original ResearchAnimalsAntigens, ViralB-LymphocytesCell NucleusCell Transformation, ViralChildChild, PreschoolChromosome DeletionDNA, ViralEpstein-Barr Virus Nuclear AntigensFemaleGenes, ViralHerpesvirus 4, HumanHumansLymphomaMaleRepetitive Sequences, Nucleic AcidRNA, ViralTranscription, GeneticTumor Virus InfectionsVirionVirus Replication
1983
Central-Nervous-System Lymphoma Related to Epstein–Barr Virus
Hochberg F, Miller G, Schooley R, Hirsch M, Feorino P, Henle W. Central-Nervous-System Lymphoma Related to Epstein–Barr Virus. New England Journal Of Medicine 1983, 309: 745-748. PMID: 6310394, DOI: 10.1056/nejm198309293091301.Peer-Reviewed Original ResearchConceptsEpstein-Barr virusCentral nervous systemSystem lymphomaPrimary lymphomaNervous systemEpstein-Barr virus-specific antibodiesEpstein-Barr virus infectionEpstein-Barr virus genomeRecent primary infectionAdjacent normal brain tissueVirus-specific antibodiesNormal brain tissueSystemic lymphomaBamHI K fragmentAdditional patientsSerologic evidenceOngoing infectionPrimary infectionVirus infectionLymphomaBrain tissueTumor tissueSerum samplesInfectionVirusIdentification of a rare Epstein-Barr virus variant that enhances early antigen expression in Raji cells.
Rabson M, Heston L, Miller G. Identification of a rare Epstein-Barr virus variant that enhances early antigen expression in Raji cells. Proceedings Of The National Academy Of Sciences Of The United States Of America 1983, 80: 2762-2766. PMID: 6302703, PMCID: PMC393908, DOI: 10.1073/pnas.80.9.2762.Peer-Reviewed Original Research
1980
Diffuse Polyclonal B-Cell Lymphoma during Primary Infection with Epstein–Barr Virus
Robinson J, Brown N, Andiman W, Halliday K, Francke U, Robert M, Andersson-Anvret M, Horstmann D, Miller G. Diffuse Polyclonal B-Cell Lymphoma during Primary Infection with Epstein–Barr Virus. New England Journal Of Medicine 1980, 302: 1293-1297. PMID: 6245364, DOI: 10.1056/nejm198006053022306.Peer-Reviewed Original Research
1974
OROPHARYNGEAL EXCRETION OF EPSTEIN-BARR VIRUS BY RENAL TRANSPLANT RECIPIENTS AND OTHER PATIENTS TREATED WITH IMMUNOSUPPRESSIVE DRUGS
Strauch B, Siegel N, Andrews L, Miller G. OROPHARYNGEAL EXCRETION OF EPSTEIN-BARR VIRUS BY RENAL TRANSPLANT RECIPIENTS AND OTHER PATIENTS TREATED WITH IMMUNOSUPPRESSIVE DRUGS. The Lancet 1974, 303: 234-237. PMID: 4130246, DOI: 10.1016/s0140-6736(74)92546-x.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultAntibodies, ViralAzathioprineCarrier StateChildChild, PreschoolFemaleFluorescent Antibody TechniqueHerpesvirus 4, HumanHumansImmunity, CellularImmunosuppressive AgentsKidney TransplantationLeukocytesMaleMiddle AgedMouthMucusPharynxPostoperative CarePrednisoneProspective StudiesTherapeutic IrrigationTransplantation, HomologousConceptsEpstein-Barr virusImmunosuppressive drugsRenal homograftsRenal transplant recipientsOropharyngeal excretionShed virusVirus excretorsImmunosuppressive therapySeropositive patientsTransplant recipientsChronic uraemiaThroat washingsVirus 8Seropositive individualsThroat samplesVirus sheddingVirus infectionPatientsNuclear antigenHealthy staffLong-term proliferationDrugsVirusHomograftsTransplantation
1973
Prolonged Oropharyngeal Excretion of Epstein–Barr Virus after Infectious Mononucleosis
Miller G, Niederman J, Andrews L. Prolonged Oropharyngeal Excretion of Epstein–Barr Virus after Infectious Mononucleosis. New England Journal Of Medicine 1973, 288: 229-232. PMID: 4345064, DOI: 10.1056/nejm197302012880503.Peer-Reviewed Original ResearchConceptsEpstein-Barr virusThroat washesInfectious mononucleosisEpstein-Barr viral antigensEpstein-Barr virus antibodiesInfectious mononucleosis syndromeUmbilical cord leukocytesOropharyngeal excretionClinical symptomsControl subjectsSerum antibodiesVirus antibodiesViral antigensBlood leukocytesSuch antigensComplement fixationContinuous cell linesFactor presentMononucleosisAntibodiesReference seraPatientsCell linesSyndromeLeukocytes
1972
Prospective study of Epstein-Barr virusinfections in acute lymphoblastic leukemia of childhood
Miller G, Shope T, Heston L, O'Brien R, Schwartz A, Pearson H. Prospective study of Epstein-Barr virusinfections in acute lymphoblastic leukemia of childhood. The Journal Of Pediatrics 1972, 80: 932-937. PMID: 4337277, DOI: 10.1016/s0022-3476(72)80004-0.Peer-Reviewed Original ResearchConceptsEBV antibodiesProspective studyLymphoblastoid cell linesAcutelymphoblastic leukemiaEpstein-Barr virus infectionAntibody-positive childrenAntibody-negative patientsEBV antibody titersAcute lymphoblastic leukemiaCourse of leukemiaCell linesEBV infectionInfectious mononucleosisUntreated patientsMaternal antibodiesCongenital leukemiaSerologic evidenceAntibody titersLymphoblastic leukemiaVirus infectionPatientsLeukemiaProgressive declineEBVUndetectable levels
1970
Trypsinized Placental Cell Cultures for the Propagation of Viruses and as “Feeder Layers”
Grogan E, Enders J, Miller G. Trypsinized Placental Cell Cultures for the Propagation of Viruses and as “Feeder Layers”. Journal Of Virology 1970, 5: 406-409. PMID: 4314557, PMCID: PMC376018, DOI: 10.1128/jvi.5.3.406-409.1970.Peer-Reviewed Original Research
1969
Establishment of Lines from Normal Human Blood Leukocytes by Co-cultivation with a Leukocyte Line Derived from a Leukemic Child 1
Miller G, Enders J, Lisco H, Kohn H. Establishment of Lines from Normal Human Blood Leukocytes by Co-cultivation with a Leukocyte Line Derived from a Leukemic Child 1. Experimental Biology And Medicine 1969, 132: 247-252. PMID: 4899209, DOI: 10.3181/00379727-132-34189.Peer-Reviewed Original ResearchConceptsCancer Research FoundationWhite blood cellsHuman placental cellsHuman blood leukocytesNormal human blood leukocytesNormal adult malesEBV antigensChildren 1Blood leukocytesPlacental cellsClinical specimensBlood cellsPossible roleEBVLeukocytesAntigenAdult malesCellsLeukocyte linesCulture system