2024
Reevaluation of ovarian cyst fine-needle aspiration cytology: A 10-year institutional experience
Takeda K, Cai G, Adeniran A, Sun T. Reevaluation of ovarian cyst fine-needle aspiration cytology: A 10-year institutional experience. American Journal Of Clinical Pathology 2024, aqae077. PMID: 38916141, DOI: 10.1093/ajcp/aqae077.Peer-Reviewed Original ResearchCystic fluid cytologyFine-needle aspirationFluid cytologyAmerican College of Obstetricians and Gynecologists guidelinesSingle-institution cohortRate of malignancySurgical pathology diagnosisFNA casesGynecologists guidelinesCytological diagnosisFNA cytologyPathological diagnosisPatient demographicsInstitutional experienceSurgical pathologyOvarian cyst fluidClinical circumstancesAmerican CollegeCytologyRadiological informationMalignancyGold standardCyst fluidModerate sensitivityPotential safety concernsImproving diagnostic yield of pancreatic serous cystadenoma with cyst fluid ancillary testing, adjunct immunohistochemistry, and additional fine‐needle biopsy sampling
Wang X, Zhang X, Hui P, Cai G. Improving diagnostic yield of pancreatic serous cystadenoma with cyst fluid ancillary testing, adjunct immunohistochemistry, and additional fine‐needle biopsy sampling. Cancer Cytopathology 2024, 132: 425-434. PMID: 38450993, DOI: 10.1002/cncy.22808.Peer-Reviewed Original ResearchDiagnosis of serous cystadenomaFine-needle biopsyFine-needle aspirationCyst fluid carcinoembryonic antigenPancreatic serous cystadenomaSerous cystadenomaAncillary testsCEA levelsCytological diagnosisFine-needle aspiration cell blocksFine-needle aspiration diagnosisFine-needle aspiration casesCyst fluid CEA levelsSerous cystadenoma casesFluid carcinoembryonic antigenLow CEA levelFine-needle biopsy samplingKRAS mutation analysisWild-type KRASConcurrent fine-needle aspirationImprove diagnostic yieldInhibin immunostainingAtypical cellsCytology casesDiagnostic yield
2023
Cytologic evaluation of upper urinary tract specimens: An institutional retrospective study using The Paris System for Reporting Urine Cytology second edition with histopathologic follow‐up
Khajir G, Sun T, Wang H, Sprenkle P, Adeniran A, Cai G, Levi A. Cytologic evaluation of upper urinary tract specimens: An institutional retrospective study using The Paris System for Reporting Urine Cytology second edition with histopathologic follow‐up. Cytopathology 2023, 35: 235-241. PMID: 37916579, DOI: 10.1111/cyt.13328.Peer-Reviewed Original ResearchHigh-grade urothelial carcinomaLow-grade urothelial carcinomaUpper urinary tractUrothelial carcinomaUrinary tractCytologic evaluationCytology specimensInstitutional retrospective studyParis SystemHigh-grade malignancyAtypical urothelial cellsCytologic categoriesRetrospective studyInstitutional databaseCytological diagnosisUrinary cytopathologyHistopathologicMalignant cellsBenign casesUrothelial cellsTPS categoryCarcinomaReporting systemTractAUCUtility of parathyroid hormone immunocytochemistry in fine needle aspiration diagnosis of parathyroid tissue
Sardana R, Abi‐Raad R, Adeniran A, Cai G. Utility of parathyroid hormone immunocytochemistry in fine needle aspiration diagnosis of parathyroid tissue. Cytopathology 2023, 34: 597-602. PMID: 37534757, DOI: 10.1111/cyt.13283.Peer-Reviewed Original ResearchConceptsParathyroid tissueFine-needle aspirationPTH casesClinicopathological characteristicsCytomorphological featuresThyroid lesionsThinPrep slidesFine needle aspiration diagnosisNeck soft tissuePatients' clinicopathological characteristicsNeedle aspiration diagnosisNegative predictive valueClinical suspicionStudy cohortPathology databaseRetrospective studyDiagnostic challengeDifferential diagnosisInstitutional experienceNeedle aspirationCytological diagnosisFNA casesAspiration diagnosisPredictive valueAdjunct test
2022
Intraductal papillary neoplasm of the bile duct: Cytomorphologic and molecular features
Stendahl K, Gilani SM, Basturk O, Hui P, Sigel C, Cai G. Intraductal papillary neoplasm of the bile duct: Cytomorphologic and molecular features. Cancer Cytopathology 2022, 131: 37-49. PMID: 36041224, PMCID: PMC9812877, DOI: 10.1002/cncy.22637.Peer-Reviewed Original ResearchConceptsIntraductal papillary neoplasmBile ductCytomorphologic featuresFine granular chromatinPapillary neoplasmVacuolated cytoplasmGranular chromatinCase of IPNBColumnar cellsComplex papillary architectureOriginal cytological diagnosisCommon bile ductCharacteristic cytomorphologic featuresHigh-grade dysplasiaMolecular featuresBackground mucinKRAS testingHepatic ductRetrospective studyAcute inflammationHistopathologic confirmationKRAS mutationsPapillary architecturePapillary clustersCytological diagnosisSignificance of KRAS mutation testing in biliary brushing cytology specimens: A 10‐year retrospective review
Sun T, Zuo T, Hui P, Cai G. Significance of KRAS mutation testing in biliary brushing cytology specimens: A 10‐year retrospective review. Cancer Cytopathology 2022, 130: 558-565. PMID: 35417072, DOI: 10.1002/cncy.22579.Peer-Reviewed Original ResearchConceptsExtrahepatic biliary stenosisKRAS mutation testingKRAS mutational analysisKRAS mutationsBiliary stenosisBiliary ductsInstitutional review board approvalResults of cytologyPancreatic duct adenocarcinomaBiliary brushing cytologyReview board approvalCytological diagnostic categoriesRetrospective reviewBiliary stricturesDuct adenocarcinomaAbsolute riskCytology examinationDuct brushingsBiliary brushingsBrushing cytologyMalignant conditionsCytological diagnosisBoard approvalClinical practiceCytology specimens
2013
Performance of endoscopic ultrasound-guided fine needle aspiration in diagnosing pancreatic neuroendocrine tumors
Bernstein J, Ustun B, Alomari A, Bao F, Aslanian HR, Siddiqui U, Chhieng D, Cai G. Performance of endoscopic ultrasound-guided fine needle aspiration in diagnosing pancreatic neuroendocrine tumors. CytoJournal 2013, 10: 10. PMID: 23858320, PMCID: PMC3709383, DOI: 10.4103/1742-6413.112648.Peer-Reviewed Original ResearchEndoscopic ultrasound-guided fine-needle aspirationPancreatic neuroendocrine tumorsUltrasound-guided fine-needle aspirationFine-needle aspirationNeuroendocrine tumorsNeedle aspirationCytological diagnosisMucinous cystic neoplasmSmall-sized tumorsDiagnosis of neoplasmRetrospective studyCystic neoplasmsRare tumorDefinite diagnosisDifferential diagnosisSized tumorsFNA diagnosisCytomorphologic featuresAtypical diagnosisDiagnostic pitfallsPatientsDiscrepant casesTumorsImmunocytochemical studyDiagnosis