2023
Folate Intake and Ovarian Cancer Risk among Women with Endometriosis: A Case–Control Study from the Ovarian Cancer Association Consortium
Gersekowski K, Ibiebele T, Group F, Doherty J, Harris H, Goodman M, Terry K, Wu A, Bandera E, Qin B, Ong J, Tyrer J, Dixon-Suen S, Modugno F, Risch H, Webb P. Folate Intake and Ovarian Cancer Risk among Women with Endometriosis: A Case–Control Study from the Ovarian Cancer Association Consortium. Cancer Epidemiology Biomarkers & Prevention 2023, 32: of1-of10. PMID: 37220873, PMCID: PMC10390886, DOI: 10.1158/1055-9965.epi-23-0121.Peer-Reviewed Original ResearchConceptsOvarian cancer riskHigh dietary folate intakeDietary folate intakeCase-control studyFolate intakeOvarian cancerOvarian Cancer Association ConsortiumCancer riskOdds ratioMendelian randomizationSelf-reported endometriosisSupplemental folate intakeHigh folate intakeHigh folate dietCancer-promoting effectsPooled analysisFolate dietPrecancerous lesionsFolate statusEndometriosisIncrease riskCancerCancer typesLogistic regressionIntake
2014
Consortium analysis of gene and gene–folate interactions in purine and pyrimidine metabolism pathways with ovarian carcinoma risk
Kelemen LE, Terry KL, Goodman MT, Webb PM, Bandera EV, McGuire V, Rossing MA, Wang Q, Dicks E, Tyrer JP, Song H, Kupryjanczyk J, Dansonka‐Mieszkowska A, Plisiecka‐Halasa J, Timorek A, Menon U, Gentry‐Maharaj A, Gayther SA, Ramus SJ, Narod SA, Risch HA, McLaughlin JR, Siddiqui N, Glasspool R, Paul J, Carty K, Gronwald J, Lubiński J, Jakubowska A, Cybulski C, Kiemeney LA, Massuger LF, van Altena A, Aben KK, Olson SH, Orlow I, Cramer DW, Levine DA, Bisogna M, Giles GG, Southey MC, Bruinsma F, Kjær S, Høgdall E, Jensen A, Høgdall CK, Lundvall L, Engelholm S, Heitz F, du Bois A, Harter P, Schwaab I, Butzow R, Nevanlinna H, Pelttari LM, Leminen A, Thompson PJ, Lurie G, Wilkens LR, Lambrechts D, Van Nieuwenhuysen E, Lambrechts S, Vergote I, Beesley J, Investigators A, Fasching P, Beckmann M, Hein A, Ekici A, Doherty J, Wu A, Pearce C, Pike M, Stram D, Chang‐Claude J, Rudolph A, Dörk T, Dürst M, Hillemanns P, Runnebaum I, Bogdanova N, Antonenkova N, Odunsi K, Edwards R, Kelley J, Modugno F, Ness R, Karlan B, Walsh C, Lester J, Orsulic S, Fridley B, Vierkant R, Cunningham J, Wu X, Lu K, Liang D, Hildebrandt M, Weber R, Iversen E, Tworoger S, Poole E, Salvesen H, Krakstad C, Bjorge L, Tangen I, Pejovic T, Bean Y, Kellar M, Wentzensen N, Brinton L, Lissowska J, Garcia‐Closas M, Campbell I, Eccles D, Whittemore A, Sieh W, Rothstein J, Anton‐Culver H, Ziogas A, Phelan C, Moysich K, Goode E, Schildkraut J, Berchuck A, Pharoah P, Sellers T, Brooks‐Wilson A, Cook L, Le N. Consortium analysis of gene and gene–folate interactions in purine and pyrimidine metabolism pathways with ovarian carcinoma risk. Molecular Nutrition & Food Research 2014, 58: 2023-2035. PMID: 25066213, PMCID: PMC4197821, DOI: 10.1002/mnfr.201400068.Peer-Reviewed Original ResearchCarcinomaCase-Control StudiesDietDietary SupplementsDihydrouracil Dehydrogenase (NADP)Energy IntakeFemaleFolic AcidFolic Acid DeficiencyGenetic Predisposition to DiseaseGenome-Wide Association StudyGlobal HealthHumansMultivariate AnalysisNeoplasm ProteinsOvarian NeoplasmsPolymorphism, Single NucleotideRisk FactorsWhite People
2003
Etiology of Pancreatic Cancer, With a Hypothesis Concerning the Role of N-Nitroso Compounds and Excess Gastric Acidity
Risch HA. Etiology of Pancreatic Cancer, With a Hypothesis Concerning the Role of N-Nitroso Compounds and Excess Gastric Acidity. Journal Of The National Cancer Institute 2003, 95: 948-960. PMID: 12837831, DOI: 10.1093/jnci/95.13.948.Peer-Reviewed Original ResearchConceptsPancreatic cancerGastric acidityRisk of nonsmokersConsumption of fruitsCurrent smokersDiabetes mellitusChronic pancreatitisCigarette smokingColorectal cancerCytokine mechanismsCancer deathDietary factorsDuodenal acidityRisk factorsEpidemiologic reviewFrequent causeHigh riskLower riskN-nitroso compoundsHelicobacter pyloriCancerGermline mutationsHost genetic variationRiskAnimal foods