2019
Evidence-Based Gardening: Using Palliative Approaches to Cure Complex Wounds.
Ching AH, Le N, Norwich-Cavanaugh A, Hsia HC. Evidence-Based Gardening: Using Palliative Approaches to Cure Complex Wounds. Annals Of Plastic Surgery 2019, 83: s45-s49. PMID: 31513065, DOI: 10.1097/sap.0000000000002100.Peer-Reviewed Original ResearchTargeting Fibrotic Signaling: A Review of Current Literature and Identification of Future Therapeutic Targets to Improve Wound Healing.
Hetzler PT, Dash BC, Guo S, Hsia HC. Targeting Fibrotic Signaling: A Review of Current Literature and Identification of Future Therapeutic Targets to Improve Wound Healing. Annals Of Plastic Surgery 2019, 83: e92-e95. PMID: 31246672, PMCID: PMC6851445, DOI: 10.1097/sap.0000000000001955.Peer-Reviewed Original ResearchConceptsTherapeutic targetAberrant wound healing processAppropriate physiologic responseMorbid disease processSurvival of myofibroblastsWound healingFibrotic signaling pathwaysTranscription factor/serum response factor (MRTF/SRF) pathwayFuture therapeutic targetsSmooth muscle actinFuture translational researchCurrent literatureFibrotic signalingTherapeutic optionsFibrotic lesionsTissue injuryWound healing processDisease processPhysiologic responsesSerum response factor pathwayMuscle actinFactor pathwayExcessive responseFibrosisTranslational researchAn Algorithm for the Management of Residual Head and Neck Melanoma In Situ Using Topical Imiquimod: A Pilot Study.
Tsay C, Kim S, Norwich-Cavanaugh A, Hsia HC, Narayan D. An Algorithm for the Management of Residual Head and Neck Melanoma In Situ Using Topical Imiquimod: A Pilot Study. Annals Of Plastic Surgery 2019, 82: s199-s201. PMID: 30855388, DOI: 10.1097/sap.0000000000001840.Peer-Reviewed Original ResearchConceptsTopical imiquimodNeck melanomaSurgical excisionCure rateAtypical squamous cell carcinomaComparable cure ratesSquamous cell carcinomaDuration of treatmentLength of treatmentFrequency of treatmentStage T1aActive inflammationStandard therapyInitial biopsyResidual inflammationPatient adherencePositive marginsResidual diseaseCell carcinomaCertain patientsSkin biopsiesComplete excisionFunctional impairmentInclusion criteriaDifficult lesions
2018
Impact of Acellular Dermal Matrix on Postsurgical Wound Fluid Biomarkers in Prosthetic Breast Reconstruction
Hsia HC, Weaver MR, Schwarzbauer JE. Impact of Acellular Dermal Matrix on Postsurgical Wound Fluid Biomarkers in Prosthetic Breast Reconstruction. Annals Of Plastic Surgery 2018, 81: s89-s96. PMID: 29851721, DOI: 10.1097/sap.0000000000001495.Peer-Reviewed Original ResearchConceptsAcellular dermal matrixProsthetic breast reconstructionInitial postoperative periodBreast reconstructionDermal matrixPostoperative periodFluid biomarkersTime pointsBody mass indexSurgical wound fluidBreast reconstruction surgeryFluid samplesMatrix metalloproteinase activitySoft tissue reinforcementExtracellular matrix protein levelsPresent groupWound fluid samplesBiologic scaffoldsSingle surgeonMass indexSurgical drainsReconstruction surgeryCell proliferation activityBlinded fashionSimilar demographics
2017
Fibroblast growth factor receptor is a mechanistic link between visceral adiposity and cancer
Chakraborty D, Benham V, Bullard B, Kearney T, Hsia HC, Gibbon D, Demireva EY, Lunt SY, Bernard JJ. Fibroblast growth factor receptor is a mechanistic link between visceral adiposity and cancer. Oncogene 2017, 36: 6668-6679. PMID: 28783178, PMCID: PMC5709202, DOI: 10.1038/onc.2017.278.Peer-Reviewed Original ResearchConceptsAdipose tissueFibroblast growth factor-2 levelsGrowth factor-2 levelsFGFR-1Cancer prevention strategiesEpithelial cellsExcess adipose tissueTumor formationFactor 2 levelsVisceral adipose tissueNovel ex vivo systemSkin tumor formationObese human donorsNon-tumorigenic epithelial cellsSoft agarEx vivo systemGrowth factor receptorAdjuvant therapyEpithelial cell growthVisceral adiposityLevels of FGF2Obese individualsEpidemiological evidenceFibroblast growth factor receptorCancer risk
2003
Differences in Breast Shape Preferences between Plastic Surgeons and Patients Seeking Breast Augmentation
Hsia HC, Thomson JG. Differences in Breast Shape Preferences between Plastic Surgeons and Patients Seeking Breast Augmentation. Plastic & Reconstructive Surgery 2003, 112: 312-320. PMID: 12832909, DOI: 10.1097/01.prs.0000066365.12348.a7.Peer-Reviewed Original Research