James Clune, MD
Associate Professor of Surgery (Plastic); Leader, Multidisciplinary Care, Melanoma Program
Research & Publications
Biography
News
Research Summary
Peripheral Nerve Research:
1) Preservation of the neuromuscular junction
2) Targeted Muscle Reinnervation
Tumor Research:
1) Isolated limb perfusion for extremity soft tissue tumors
2) Sentinel Lymph Node outcomes in melanoma
Extensive Research Description
Tumor immunology; Tumor genetics
Coauthors
Research Interests
Surgical Oncology
Selected Publications
- 08. Proteomic Profiling of Tumor Microenvironment In Desmoplastic Melanoma Using The Nanostring Geomx Digital Spatial ProfilerSu D, Galan A, Schoenfeld D, Ibrahim W, Cabrejo R, Baumann R, Rimm D, Khan S, Kluger H, Olino K, Clune J. 08. Proteomic Profiling of Tumor Microenvironment In Desmoplastic Melanoma Using The Nanostring Geomx Digital Spatial Profiler. Plastic & Reconstructive Surgery Global Open 2024, 12: 6-6. PMCID: PMC11041221, DOI: 10.1097/01.gox.0001015124.74133.52.
- Digital spatial proteomic profiling reveals immune checkpoints as biomarkers in lymphoid aggregates and tumor microenvironment of desmoplastic melanomaSu D, Schoenfeld D, Ibrahim W, Cabrejo R, Djureinovic D, Baumann R, Rimm D, Khan S, Halaban R, Kluger H, Olino K, Galan A, Clune J. Digital spatial proteomic profiling reveals immune checkpoints as biomarkers in lymphoid aggregates and tumor microenvironment of desmoplastic melanoma. Journal For ImmunoTherapy Of Cancer 2024, 12: e008646. PMID: 38519058, PMCID: PMC10961546, DOI: 10.1136/jitc-2023-008646.
- Immunotherapy Initiation at the End of Life in Patients With Metastatic Cancer in the USKerekes D, Frey A, Prsic E, Tran T, Clune J, Sznol M, Kluger H, Forman H, Becher R, Olino K, Khan S. Immunotherapy Initiation at the End of Life in Patients With Metastatic Cancer in the US. JAMA Oncology 2024, 10: 342-351. PMID: 38175659, PMCID: PMC10767643, DOI: 10.1001/jamaoncol.2023.6025.
- Immunotherapy utilization in stage IIIA melanoma: less may be moreFrey A, Kerekes D, Khan S, Tran T, Kluger H, Clune J, Ariyan S, Sznol M, Ishizuka J, Olino K. Immunotherapy utilization in stage IIIA melanoma: less may be more. Frontiers In Oncology 2024, 14: 1336441. PMID: 38380358, PMCID: PMC10876869, DOI: 10.3389/fonc.2024.1336441.
- 1107 Enhancing immune responses to melanoma with the RIG-I antiviral pathway agonist SLR14Perry C, Frey A, Ton W, Mackie M, Ouerghi F, Wei J, Clulo K, He M, Dumit T, Ding M, Guo W, Clune J, Olino K, Ishizuka J. 1107 Enhancing immune responses to melanoma with the RIG-I antiviral pathway agonist SLR14. 2023, a1219-a1219. DOI: 10.1136/jitc-2023-sitc2023.1107.
- The Facial Artery Perforator FlapLewis K, Islam S, Phillips S, Carney M, Clune J. The Facial Artery Perforator Flap. Journal Of Craniofacial Surgery 2023, 34: e434-e437. PMID: 36914599, DOI: 10.1097/scs.0000000000009249.
- Upper Extremity VariationsKim S, Xu X, Clune J, Narayan D. Upper Extremity Variations. 2020, 375-418. DOI: 10.1007/978-3-030-55660-0_17.
- Upper and Lower Extremity Vascular VariationsXu X, Kim S, Clune J, Narayan D. Upper and Lower Extremity Vascular Variations. 2020, 437-466. DOI: 10.1007/978-3-030-55660-0_19.
- Functional Neck DissectionPatel A, Clune J, Ariyan S. Functional Neck Dissection. Plastic & Reconstructive Surgery 2016, 138: 1084-1086. PMID: 27783008, DOI: 10.1097/prs.0000000000002705.
- Malignant MelanomaPavri SN, Clune J, Ariyan S, Narayan D. Malignant Melanoma. Plastic & Reconstructive Surgery 2016, 138: 330e-340e. PMID: 27465194, DOI: 10.1097/prs.0000000000002367.
- Surgical Reconstruction in MelanomaClune JE, Narayan D. Surgical Reconstruction in Melanoma. Current Problems In Cancer 2011, 35: 185-199. PMID: 21911182, DOI: 10.1016/j.currproblcancer.2011.07.006.
- Excising Value at a Marginal Cost: Rethinking the Management of Basal Cell CarcinomaPatel A, Clune JE, Mody P, Price G, Ariyan S. Excising Value at a Marginal Cost: Rethinking the Management of Basal Cell Carcinoma. Plastic & Reconstructive Surgery 2011, 127: 2136-2137. PMID: 21532456, DOI: 10.1097/prs.0b013e31820e9405.
- Autologous cranial particulate bone graft: an experimental study of onlay cranioplasty.Clune JE, Mulliken JB, Glowacki J, Arany PR, Kulungowski AM, Rogers GF, Greene AK. Autologous cranial particulate bone graft: an experimental study of onlay cranioplasty. The Journal Of Craniofacial Surgery 2011, 22: 319-23. PMID: 21239926, DOI: 10.1097/SCS.0b013e3181f7e0e2.
- Inlay cranioplasty: an experimental comparison of particulate graft versus bone dust.Clune JE, Mulliken JB, Glowacki J, Rogers GF, Arany PR, Kulungowski AM, Greene AK. Inlay cranioplasty: an experimental comparison of particulate graft versus bone dust. Plastic And Reconstructive Surgery 2010, 126: 1311-1319. PMID: 20885252, DOI: 10.1097/PRS.0b013e3181ea4524.
- Perioperative corticosteroid reduces hospital stay after fronto-orbital advancement.Clune JE, Greene AK, Guo CY, Gao LL, Kim S, Meara JG, Proctor MR, Mulliken JB, Rogers GF. Perioperative corticosteroid reduces hospital stay after fronto-orbital advancement. The Journal Of Craniofacial Surgery 2010, 21: 344-8. PMID: 20186083, DOI: 10.1097/SCS.0b013e3181cf6103.
- Nipple adenoma in infancy.Clune JE, Kozakewich HP, VanBeek CA, Labow BI, Greene AK. Nipple adenoma in infancy. Journal Of Pediatric Surgery 2009, 44: 2219-22. PMID: 19944237, DOI: 10.1016/j.jpedsurg.2009.08.020.