Featured Publications
Dose and Volume De-Escalation for Elective Nodal Regions in Patients With Human Papillomavirus (HPV)-Positive Oropharyngeal Cancer (OPC) Undergoing Curative-Intent Concurrent Chemoradiation (CCRT)
Tsai C, McBride S, Riaz N, Kang J, Spielsinger D, Waldenberg T, Yu Y, Chen L, Zakeri K, Wong R, Dunn L, Sherman E, Lee N. Dose and Volume De-Escalation for Elective Nodal Regions in Patients With Human Papillomavirus (HPV)-Positive Oropharyngeal Cancer (OPC) Undergoing Curative-Intent Concurrent Chemoradiation (CCRT). International Journal Of Radiation Oncology • Biology • Physics 2021, 111: s142-s143. DOI: 10.1016/j.ijrobp.2021.07.321.Peer-Reviewed Original ResearchConcurrent chemoradiationDe-escalation strategiesOropharyngeal cancerGross diseaseNodal recurrenceDisease recurrenceOPC patientsLevel IbHPV-positive OPC patientsLocoregional recurrence-free survivalElective nodal regionsFavorable locoregional controlFeeding tube dependenceHigh-dose cisplatinPositive oropharyngeal cancerPrimary concurrent chemoradiationRecurrence-free survivalNode-positive neckFeeding tube placementLong-term resultsNode-negative neckDe-escalation approachMATERIAL/METHODSHigh control ratesRadiation treatment plans
2020
Beyond reirradiation: Efficacy and safety of three or more courses of radiation for head and neck malignancies
Xu AJ, Luo L, Leeman JE, Romesser PB, Spielsinger D, Sabol C, Waldenberg T, Brinkman T, Riaz N, McBride S, Kang J, Lee N, Tsai CJ. Beyond reirradiation: Efficacy and safety of three or more courses of radiation for head and neck malignancies. Clinical And Translational Radiation Oncology 2020, 23: 30-34. PMID: 32382663, PMCID: PMC7200775, DOI: 10.1016/j.ctro.2020.04.009.Peer-Reviewed Original ResearchCourse of radiationMedian local recurrence-free survivalNeck regionLocal recurrence-free survivalGrade 5 toxicityMedian overall survivalRecurrence-free survivalSingle-institution databaseFree survivalOverall survivalSelect patientsSystemic therapyNeck malignanciesRecurrent headSignificant morbiditySubsequent therapyNeck cancerMulti-disciplinary teamGrade 3Institution's databasePatientsLocal controlReirradiationTreatment planMultiple courses