Featured Publications
Oropharyngeal Carcinoma
Husain Z, Kang J, Lee N, Poon I. Oropharyngeal Carcinoma. Practical Guides In Radiation Oncology 2022, 15-25. DOI: 10.1007/978-3-030-99590-4_2.Peer-Reviewed Original ResearchLong-term treatment toxicityOropharyngeal squamous cell carcinomaCurative treatment optionSquamous cell carcinomaPatterns of failureElective coverageOropharyngeal carcinomaTreatment toxicityNeck malignanciesAccurate target delineationCell carcinomaDisease stageTreatment optionsCurative potentialPhysical examCommon headClinical scenariosRadiation oncologistsSurgical anatomyTarget volumeTarget delineationVolume coverageCarcinomaMultimodal imagingPrimary target
2022
Peer Review of Head and Neck Cancer Planning Target Volumes in Radiation Oncology
Hesse J, Zakeri K, Chen L, Yu Y, Kang J, Riaz N, Tsai C, McBride S, Gelblum D, Lee N. Peer Review of Head and Neck Cancer Planning Target Volumes in Radiation Oncology. International Journal Of Radiation Oncology • Biology • Physics 2022, 114: e472-e473. DOI: 10.1016/j.ijrobp.2022.07.1729.Peer-Reviewed Original ResearchStart of RTTarget volumeFurther workupNeck cancerTreatment planPositive findingsNeck radiation oncologistMinority of patientsOverall treatment planTreatment planningPlanning target volumeProspective peer reviewTumor board discussionMATERIAL/METHODSNeck cancer casesRadiation treatment plansFurther surgeryUnderwent biopsyAdditional surgeryAdditional workupOncology servicesSignificant changesCancer casesPatientsRadiation oncologistsEvaluation of Substantial Reduction in Elective Radiotherapy Dose and Field in Patients With Human Papillomavirus–Associated Oropharyngeal Carcinoma Treated With Definitive Chemoradiotherapy
Tsai CJ, McBride SM, Riaz N, Kang JJ, Spielsinger DJ, Waldenberg T, Gelblum D, Yu Y, Chen LC, Zakeri K, Wong RJ, Dunn L, Pfister DG, Sherman EJ, Lee NY. Evaluation of Substantial Reduction in Elective Radiotherapy Dose and Field in Patients With Human Papillomavirus–Associated Oropharyngeal Carcinoma Treated With Definitive Chemoradiotherapy. JAMA Oncology 2022, 8: 364-372. PMID: 35050342, PMCID: PMC8778604, DOI: 10.1001/jamaoncol.2021.6416.Peer-Reviewed Original ResearchConceptsDistant metastasis-free survivalProgression-free survivalMetastasis-free survivalOropharyngeal carcinomaConcurrent chemoradiotherapyDe-escalation strategiesRadiotherapy doseTotal doseSubclinical regionsLocoregional controlGross diseaseCohort studyOverall survivalClinical outcomesHuman Papillomavirus–Associated Oropharyngeal CarcinomaHigh-dose cisplatin therapyHPV-positive oropharyngeal carcinomaTarget volumeBilateral level IBGy of radiotherapyPrimary concurrent chemoradiotherapyRetrospective cohort studyFavorable clinical outcomeAmerican Joint CommitteeLong-term followPeer Review of Head and Neck Cancer Planning Target Volumes in Radiation Oncology
Hesse J, Chen L, Yu Y, Kang J, Riaz N, Tsai C, McBride S, Gelblum D, Zakeri K, Lee N. Peer Review of Head and Neck Cancer Planning Target Volumes in Radiation Oncology. Advances In Radiation Oncology 2022, 7: 100917. PMID: 35647395, PMCID: PMC9133360, DOI: 10.1016/j.adro.2022.100917.Peer-Reviewed Original ResearchStart of RTAdditional workupTarget volumeAdditional surgeryNeck cancerTreatment planPositive findingsNeck radiation oncologistMinority of patientsOverall treatment planTreatment planningPlanning target volumeProspective peer reviewTumor board discussionNeck cancer casesRadiation treatment plansUnderwent biopsyMedical oncologistsSignificant changesCancer casesAdditional consultationPatientsRadiation oncologistsRadiation therapy planningTreatment volume