2019
Improving Care for Sickle Cell Pain Crisis Using a Multidisciplinary Approach
Balsamo L, Shabanova V, Carbonella J, Szondy MV, Kalbfeld K, Thomas DA, Santucci K, Grossman M, Pashankar F. Improving Care for Sickle Cell Pain Crisis Using a Multidisciplinary Approach. Pediatrics 2019, 143: e20182218. PMID: 30944154, DOI: 10.1542/peds.2018-2218.Peer-Reviewed Original ResearchConceptsVaso-occlusive crisisHospital daysReadmission ratesHospital costsSickle cell disease vaso-occlusive crisisMultidisciplinary quality improvement projectSickle cell pain crisisThirty-day readmission ratesDedicated team effortSCD pediatric patientsPatients ages 0Direct hospital costsLength of stayHigh usersStudy-Act methodologyQuality improvement projectMental health providersHigh-use groupPain planPain crisisFrequent hospitalizationsRisk patientsPediatric patientsPreintervention periodEmergency department
2018
Long‐term psychological and educational outcomes for survivors of neuroblastoma: A report from the Childhood Cancer Survivor Study
Zheng DJ, Krull KR, Chen Y, Diller L, Yasui Y, Leisenring W, Brouwers P, Howell R, Lai J, Balsamo L, Oeffinger KC, Robison LL, Armstrong GT, Kadan‐Lottick N. Long‐term psychological and educational outcomes for survivors of neuroblastoma: A report from the Childhood Cancer Survivor Study. Cancer 2018, 124: 3220-3230. PMID: 29888538, PMCID: PMC6168938, DOI: 10.1002/cncr.31379.Peer-Reviewed Original ResearchConceptsBehavior Problem IndexPsychological impairmentChronic health conditionsNeuroblastoma survivorsElevated riskAdult educational attainmentMultivariate log-binomial modelsMore chronic health conditionsPrevalence of impairmentPsychological functioningHealth conditionsAttention deficitsChildhood cancer survivorsAntisocial behaviorHigh-risk groupAnxiety/depressionEducational attainmentSocial withdrawalLog-binomial modelsNeurotoxic treatmentMedian agePeripheral neuropathyYear survivorsPulmonary diseaseCancer survivors
2017
Longitudinal analysis of quality‐of‐life outcomes in children during treatment for acute lymphoblastic leukemia: A report from the Children's Oncology Group AALL0932 trial
Zheng DJ, Lu X, Schore RJ, Balsamo L, Devidas M, Winick NJ, Raetz EA, Loh ML, Carroll WL, Sung L, Hunger SP, Angiolillo AL, Kadan‐Lottick N. Longitudinal analysis of quality‐of‐life outcomes in children during treatment for acute lymphoblastic leukemia: A report from the Children's Oncology Group AALL0932 trial. Cancer 2017, 124: 571-579. PMID: 29112230, PMCID: PMC5808870, DOI: 10.1002/cncr.31085.Peer-Reviewed Original ResearchConceptsAverage-risk acute lymphoblastic leukemiaQuality of lifeEmotional impairmentsLife Inventory (PedsQL) Generic CoreHigh-risk patientsProspective cohort studyTime of diagnosisEnd of therapyAcute lymphoblastic leukemiaFamily-based interventionsCohort studyQoL impairmentMean ageLymphoblastic leukemiaQOL outcomesPediatric QualityProportion of individualsEarly screeningPopulation normsImpaired rangeImpairmentMonthsTime pointsFunctioning impairmentImpairment patterns
2016
Prevalence and predictors of anxiety and depression after completion of chemotherapy for childhood acute lymphoblastic leukemia: A prospective longitudinal study
Kunin-Batson AS, Lu X, Balsamo L, Graber K, Devidas M, Hunger SP, Carroll WL, Winick NJ, Mattano LA, Maloney KW, Kadan-Lottick NS. Prevalence and predictors of anxiety and depression after completion of chemotherapy for childhood acute lymphoblastic leukemia: A prospective longitudinal study. Cancer 2016, 122: 1608-1617. PMID: 27028090, PMCID: PMC4860039, DOI: 10.1002/cncr.29946.Peer-Reviewed Original ResearchConceptsAcute lymphoblastic leukemiaCompletion of treatmentGreater riskEmotional-behavioral functioningChildren's Oncology Group protocolsChildhood acute lymphoblastic leukemiaAdjusted longitudinal analysesCompletion of chemotherapyDepressive symptoms 6 monthsSymptoms 6 monthsEmotional distressElevated anxiety scoresAnxiety 1 monthStandardized rating scalesElevated depression scoresChildren's emotional-behavioral functioningLymphoblastic leukemiaPredictors of anxietySocial support copingMeasures of copingDepressive symptomsGeneral populationDepression scoresPsychosocial interventionsEarly screening
2015
Prospective, longitudinal assessment of quality of life in children from diagnosis to 3 months off treatment for standard risk acute lymphoblastic leukemia: Results of Children's Oncology Group study AALL0331
Mitchell H, Lu X, Myers RM, Sung L, Balsamo LM, Carroll WL, Raetz E, Loh ML, Mattano LA, Winick NJ, Devidas M, Hunger SP, Maloney K, Kadan-Lottick N. Prospective, longitudinal assessment of quality of life in children from diagnosis to 3 months off treatment for standard risk acute lymphoblastic leukemia: Results of Children's Oncology Group study AALL0331. International Journal Of Cancer 2015, 138: 332-339. PMID: 26235006, PMCID: PMC5138856, DOI: 10.1002/ijc.29708.Peer-Reviewed Original ResearchConceptsStandard-risk acute lymphoblastic leukemiaAcute lymphoblastic leukemiaLymphoblastic leukemiaLife Inventory 4.0 Generic Core ScalesChildren's Oncology Group studyHRQoL 1 monthMean PedsQL scoresYears of therapyHealth-related qualityEnd of inductionHigh cure ratesGeneric Core ScalesSocial functioningRepeated-measures analysisTherapy completionTherapeutic trialsCure ratePediatric QualityPedsQL scoresConsiderable impairmentLongitudinal assessmentDiagnosisTherapyMonthsGroup study
2014
Family life events in the first year of acute lymphoblastic leukemia therapy: A children's oncology group report
Lau S, Lu X, Balsamo L, Devidas M, Winick N, Hunger SP, Carroll W, Stork L, Maloney K, Kadan‐Lottick N. Family life events in the first year of acute lymphoblastic leukemia therapy: A children's oncology group report. Pediatric Blood & Cancer 2014, 61: 2277-2284. PMID: 25175168, PMCID: PMC4282930, DOI: 10.1002/pbc.25195.Peer-Reviewed Original ResearchConceptsAcute lymphoblastic leukemiaChildren's Oncology Group reportChildhood acute lymphoblastic leukemiaAcute lymphoblastic leukemia therapyMonths of therapyProspective cohort studyAppropriate anticipatory guidanceHigh cure ratesLong-term outcomesMore childrenHealth care providersLess maternal educationFirst yearCohort studyPatient factorsCure rateLymphoblastic leukemiaCOG protocolsCare providersAnticipatory guidanceEligibility criteriaHigh incidenceLeukemia therapyMaternal educationAverage riskA prospective study of anxiety, depression, and behavioral changes in the first year after a diagnosis of childhood acute lymphoblastic leukemia
Myers RM, Balsamo L, Lu X, Devidas M, Hunger SP, Carroll WL, Winick NJ, Maloney KW, Kadan‐Lottick N. A prospective study of anxiety, depression, and behavioral changes in the first year after a diagnosis of childhood acute lymphoblastic leukemia. Cancer 2014, 120: 1417-1425. PMID: 24473774, PMCID: PMC4319360, DOI: 10.1002/cncr.28578.Peer-Reviewed Original ResearchMeSH KeywordsAggressionAntineoplastic Combined Chemotherapy ProtocolsAnxietyAsparaginaseBehaviorChildChild, PreschoolCohort StudiesCyclophosphamideDepressionDexamethasoneEmotionsFemaleHumansLongitudinal StudiesMalePolyethylene GlycolsPrecursor Cell Lymphoblastic Leukemia-LymphomaProspective StudiesPsychomotor AgitationVincristineConceptsStandard-risk acute lymphoblastic leukemiaAcute lymphoblastic leukemiaLymphoblastic leukemiaUnhealthy family functioningHispanic ethnicityChildren's Oncology Group protocolsChildhood acute lymphoblastic leukemiaClinical rangeSubpopulation of patientsWorse physical functioningMore childrenFirst yearCoping Health InventoryCohort studyProspective studyRisk factorsPhysical functioningFamily functioningHealth InventoryFamily Assessment DevicePopulation normsMonthsFunctioning ScaleDepressionGroup protocol
2006
Language lateralization and the role of the fusiform gyrus in semantic processing in young children
Balsamo LM, Xu B, Gaillard WD. Language lateralization and the role of the fusiform gyrus in semantic processing in young children. NeuroImage 2006, 31: 1306-1314. PMID: 16545581, DOI: 10.1016/j.neuroimage.2006.01.027.Peer-Reviewed Original ResearchMeSH KeywordsAge FactorsBrain MappingCerebral CortexChildChild, PreschoolDecision MakingDominance, CerebralFemaleFrontal LobeHumansImage Processing, Computer-AssistedMagnetic Resonance ImagingMaleMotor CortexNeuropsychological TestsOxygenPsychomotor PerformanceReaction TimeReadingSemanticsSpeech PerceptionConceptsSemantic processingFusiform gyrusEarly word recognition processesAuditory semantic processingWord recognition processesAdult language processingSemantic decision taskSemantic category decisionsLeft fusiform gyrusPrevious neuroimaging findingsLeft-lateralized patternYoung childrenPattern of activationLanguage comprehensionDecision taskCategory decisionsTask accuracyTask difficultyLanguage developmentLanguage lateralizationFMRI techniquesLanguage processingBrain regionsCortical regionsNeuroimaging findings
2003
Auditory comprehension of language in young children
Ahmad Z, Balsamo L, Sachs B, Xu B, Gaillard W. Auditory comprehension of language in young children. Neurology 2003, 60: 1598-1605. PMID: 12771248, DOI: 10.1212/01.wnl.0000059865.32155.86.Peer-Reviewed Original ResearchConceptsAuditory comprehensionTemporal gyrusYoung childrenLeft middle temporal gyrusAuditory language processingSuperior temporal sulcusRight-handed childrenMiddle temporal gyrusSuperior temporal gyrusLanguage fMRI studyTemporal sulcusLateralized activationFMRI studyAngular gyrusLanguage organizationIndividual subject dataLanguage processingTemporal regionsBrain regionsControl conditionFrontal lobeAge 5GyrusSignificant activationFMRIfMRI identifies regional specialization of neural networks for reading in young children
Gaillard WD, Balsamo LM, Ibrahim Z, Sachs BC, Xu B. fMRI identifies regional specialization of neural networks for reading in young children. Neurology 2003, 60: 94-100. PMID: 12525725, DOI: 10.1212/wnl.60.1.94.Peer-Reviewed Original ResearchConceptsMiddle frontal gyrusFrontal gyrusTemporal-occipital junctionMiddle temporal gyrusYoung childrenSupplementary motor areaFusiform gyrusLanguage networkTemporal gyrusOccipital junctionLanguage lateralizationNative EnglishEarly readersWernicke's areaNeural networkMotor areaBrain regionsCognitive networksAge 6Prominent activationGyrusFMRIChildren 7Interest approachBOLD technique