2020
The Relationship between ER Stress and Protein Quality Control at the Translocon
Broshar C, Buchanan B, Mehrtash A, Runnebohm A, Snow B, Scanameo L, Hochstrasser M, Rubenstein E. The Relationship between ER Stress and Protein Quality Control at the Translocon. The FASEB Journal 2020, 34: 1-1. DOI: 10.1096/fasebj.2020.34.s1.00497.Peer-Reviewed Original ResearchProtein quality controlUbiquitin-proteasome systemER stressUbiquitin ligaseDegradation signalProtein quality control mechanismsHrd1 ubiquitin ligaseTranslocon-associated proteinLipid homeostasisStress-sensing mechanismsStress-responsive mechanismsQuality control mechanismsDegradation of proteinsERAD pathwayModel organismsEndoplasmic reticulum stressProtein misfoldingAberrant proteinsERADImpairs degradationProtein degradationProteins misfoldHeat shockEndoplasmic reticulumProtein
1987
Chromosome structure in four wild-type polytene tissues of Drosophila melanogaster
Hochstrasser M. Chromosome structure in four wild-type polytene tissues of Drosophila melanogaster. Chromosoma 1987, 95: 197-208. PMID: 3111801, DOI: 10.1007/bf00330351.Peer-Reviewed Original ResearchConceptsHeat shockPuffing patternChromosome banding patternsDetailed cytogenetic analysisPolytene tissuesChromosome structureDrosophila melanogasterHsp70 geneMiddle midgutSystematic screenLarval organsMidgut cellsTranscriptional activityProthoracic glandsBanding patternsIntact nucleiLociSalivary glandsMidgutLarvaeCytogenetic analysisFold differenceRelative activityUnexpected differencesMelanogaster