2022
Orientia tsutsugamushi OtDUB Is Expressed and Interacts with Adaptor Protein Complexes during Infection
Adcox H, Berk J, Hochstrasser M, Carlyon J. Orientia tsutsugamushi OtDUB Is Expressed and Interacts with Adaptor Protein Complexes during Infection. Infection And Immunity 2022, 90: e00469-22. PMID: 36374099, PMCID: PMC9753657, DOI: 10.1128/iai.00469-22.Peer-Reviewed Original ResearchConceptsObligate intracellular lifestyleClathrin adaptor protein complex 1Adaptor protein complex 1Non-integral membrane proteinsAdaptor protein complexesHost endocytic pathwayMembrane traffic regulatorsCell wall proteinsWall proteinsProtein complexesIntracellular lifestyleRho GTPasesAdapter proteinEndocytic pathwayMembrane proteinsUbiquitin bindingCellular pathwaysCell wallStructured illumination microscopyPhospholipid phosphatidylserineIntact bacteriaO. tsutsugamushi infectionProteinRecombinant versionInteractome
2010
Chapter 161 The Ubiquitin–Proteasome System
Hochstrasser M. Chapter 161 The Ubiquitin–Proteasome System. 2010, 1293-1296. DOI: 10.1016/b978-0-12-374145-5.00161-3.Peer-Reviewed Original ResearchUbiquitin-proteasome systemC-terminusMultimeric protein complexesMultiple ubiquitin moietiesFree ubiquitin poolMost DUBsUbiquitin additionUbiquitin removalUbiquitylated proteinsIndividual physiological functionsProtein complexesE1 enzymeUbiquitin moietiesUbiquitin genesUbiquitin ligationIntrinsic subunitsUbiquitin sequenceAcceptor proteinsIsopeptide bondsUbiquitin poolsUbiquitinPhysiological functionsPrecursor formDUBsIntracellular nucleophiles