Innate acting memory Th1 cells modulate heterologous diseases
Rakebrandt N, Yassini N, Kolz A, Schorer M, Lambert K, Goljat E, Brull A, Rauld C, Balazs Z, Krauthammer M, Carballido J, Peters A, Joller N. Innate acting memory Th1 cells modulate heterologous diseases. Proceedings Of The National Academy Of Sciences Of The United States Of America 2024, 121: e2312837121. PMID: 38838013, PMCID: PMC11181110, DOI: 10.1073/pnas.2312837121.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsImmunity, InnateImmunologic MemoryInterferon-gammaInterleukin-12Legionella pneumophilaMemory T CellsMiceMice, Inbred C57BLMultiple SclerosisTh1 CellsConceptsIFN-gAutoimmune model of multiple sclerosisIFN-g productionInnate-like responsesMemory Th1 cellsModel of multiple sclerosisResponse to IL-12T helper 1Heterologous challengeTh1 cellsAutoimmune modelsIL-33IL-12Immune memoryDisease onsetIL-18Viral infectionUnrelated diseaseMultiple sclerosisDiseaseEnhanced responseInfectionHeterologous diseasesCellsRechallenge