2024
Targetable ERBB2/HER2 Mutations in Gynecologic Malignancies: Clinicopathological, Immunohistochemical, and Molecular Correlations.
Manrai P, McHenry A, Sun T, Santin A, Ratner E, Lin D, Elvin J, Hui P, Buza N. Targetable ERBB2/HER2 Mutations in Gynecologic Malignancies: Clinicopathological, Immunohistochemical, and Molecular Correlations. International Journal Of Gynecological Pathology 2024 PMID: 38914011, DOI: 10.1097/pgp.0000000000001050.Peer-Reviewed Original ResearchEndometrial carcinomaGynecologic malignanciesTyrosine kinase domainHER2-mutated non-small cell lung cancerTargeted anti-HER2 therapyNon-small cell lung cancerHigh-grade endometrioid adenocarcinomasFam-trastuzumab deruxtecanOvarian mucinous adenocarcinomaAnti-HER2 therapyAnti-HER2 drugsHER2 3+US Food and Drug AdministrationCell lung cancerEndometrial serous carcinomaSolid tumor typesStandard treatment recommendationsFood and Drug AdministrationFluorescence in situ hybridizationGynecological cancer typesEndometrial primaryMullerian originSerous carcinomaHER2 IHCEndometrioid adenocarcinoma
2021
Uterine Epithelial Neoplasia
Hui P, Flynn C, Quddus M. Uterine Epithelial Neoplasia. Practical Anatomic Pathology 2021, 113-130. DOI: 10.1007/978-3-030-68608-6_5.Peer-Reviewed Original ResearchCommon endometrioid adenocarcinomaClear cell carcinomaHigh-grade carcinomaGestational alterationsEndometrial malignancyCurettage specimenEndometrial hyperplasiaEndometrial polypsEndometrial cancerEndometrioid adenocarcinomaHistological typeAtypical hyperplasiaCell carcinomaDedifferentiated carcinomaMixed carcinomasNeuroendocrine carcinomaNonneoplastic lesionsPreneoplastic conditionsInflammatory processPrognostic informationUndifferentiated carcinomaEpithelial neoplasiaSmall biopsiesCarcinomaMolecular classification
2017
Comprehensive Analysis of PAX8 Expression in Epithelial Malignancies of the Uterine Cervix
Wong S, Hong W, Hui P, Buza N. Comprehensive Analysis of PAX8 Expression in Epithelial Malignancies of the Uterine Cervix. International Journal Of Gynecological Pathology 2017, 36: 101-106. PMID: 27362905, DOI: 10.1097/pgp.0000000000000309.Peer-Reviewed Original ResearchConceptsSquamous cell carcinomaEpithelial malignanciesPAX8 expressionAdenosquamous carcinomaMajority of SCCsCervical squamous cell carcinomaPossible primary sitesEndometrioid-type tumorsWeak nuclear stainingTissue microarray slidesGynecologic malignanciesEndometrial adenocarcinomaEndometrioid adenocarcinomaMetastatic lesionsEndometrial carcinomaMetastatic sitesUterine cervixCell carcinomaCervical tumorsEndocervical adenocarcinomaDifferential diagnosisPrimary siteAdenocarcinomaCarcinomaMalignancy
2013
Cancerous ‘floater’: a lesson learned about tissue identity testing, endometrial cancer and microsatellite instability
Bossuyt V, Buza N, Ngo NT, Much MA, Asis MC, Schwartz PE, Hui P. Cancerous ‘floater’: a lesson learned about tissue identity testing, endometrial cancer and microsatellite instability. Modern Pathology 2013, 26: 1264-1269. PMID: 23558568, DOI: 10.1038/modpathol.2013.63.Peer-Reviewed Original ResearchConceptsEndometrial curettageBackground endometriumStaging surgeryEndometrial cancerEndometrial polypsEndometrioid adenocarcinomaEndometrial adenocarcinomaFurther workupPap smearSecretory endometriumDiagnostic workupEndometrial cellsDNA genotypingAdenocarcinoma tissuesMolecular testingMicrosatellite instabilityAllelic patternsAdenocarcinomaPatientsConfirmation of contaminationTissue fragmentsCurettageEndometriumWorkupMolecular pathologists
2010
Endometrial Epithelial Neoplasms
Chhieng D, Hui P. Endometrial Epithelial Neoplasms. Current Clinical Pathology 2010, 87-105. DOI: 10.1007/978-1-60761-164-6_6.Peer-Reviewed Original ResearchCell carcinomaCommon endometrioid adenocarcinomaSquamous cell carcinomaTransitional cell carcinomaClear cell carcinomaHigh-grade carcinomaGestational alterationsEndometrial malignancyCurettage specimenEndometrial hyperplasiaEndometrial polypsEndometrioid adenocarcinomaHistological typeMucinous carcinomaMucinous componentAtypical hyperplasiaEndometrioid carcinomaMixed carcinomasNonneoplastic lesionsPreneoplastic conditionsInflammatory processUndifferentiated carcinomaEpithelial neoplasmsCarcinomaSmall biopsies