2024
The protective effect of dietary folate intake on gastric cancer is modified by alcohol consumption: A pooled analysis of the StoP Consortium
Gonzalez‐Palacios S, Compañ‐Gabucio L, Torres‐Collado L, Oncina‐Canovas A, García‐de‐la‐Hera M, Collatuzzo G, Negri E, Pelucchi C, Rota M, López‐Carrillo L, Lunet N, Morais S, Ward M, Martin V, Lozano‐Lorca M, Malekzadeh R, Pakseresht M, Hernández‐Ramírez R, Bonzi R, Patel L, López‐Cervantes M, Rabkin C, Tsugane S, Hidaka A, Trichopoulou A, Karakatsani A, Camargo M, Curado M, Zhang Z, La Vecchia C, Boffetta P, Vioque J. The protective effect of dietary folate intake on gastric cancer is modified by alcohol consumption: A pooled analysis of the StoP Consortium. International Journal Of Cancer 2024, 155: 1367-1375. PMID: 38757245, PMCID: PMC11326987, DOI: 10.1002/ijc.35004.Peer-Reviewed Original ResearchDietary folate intakeHigh folate intakeFolate intakeRisk of GCOdds ratioGastric cancerAlcoholic drinks/dayAlcohol consumptionEffect of dietary folate intakeEffect of folate intakeQuartile of folate intakeFood frequency questionnaireCalculate adjusted odds ratiosCase-control studyConfidence intervalsAdjusted odds ratiosFrequency questionnaireGC casesGC riskPooled analysisQuartile incrementLowest quartileLow riskLinear mixed modelsModifiable factors
2023
Yoghurt Intake and Gastric Cancer: A Pooled Analysis of 16 Studies of the StoP Consortium
Collatuzzo G, Negri E, Pelucchi C, Bonzi R, Turati F, Rabkin C, Liao L, Sinha R, Palli D, Ferraroni M, López-Carrillo L, Lunet N, Morais S, Albanes D, Weinstein S, Parisi D, Zaridze D, Maximovitch D, Dierssen-Sotos T, Jiménez-Moleón J, Vioque J, de la Hera M, Curado M, Dias-Neto E, Hernández-Ramírez R, López-Cervantes M, Ward M, Tsugane S, Hidaka A, Lagiou A, Lagiou P, Zhang Z, Trichopoulou A, Karakatsani A, Camargo M, La Vecchia C, Boffetta P. Yoghurt Intake and Gastric Cancer: A Pooled Analysis of 16 Studies of the StoP Consortium. Nutrients 2023, 15: 1877. PMID: 37111097, PMCID: PMC10147010, DOI: 10.3390/nu15081877.Peer-Reviewed Original ResearchConceptsGastric cancerYoghurt intakeYoghurt consumptionOdds ratioMultivariable unconditional logistic regression modelStomach cancer Pooling (StoP) ProjectStudy-specific odds ratiosUnconditional logistic regression modelsFood frequency questionnairePopulation-based studyConfidence intervalsIntestinal gastric cancerLogistic regression modelsFrequency questionnaireIntestinal casesPooled analysisProtective effectPooling ProjectGut microbiotaGC casesDisease riskGC riskAdditional studiesIntakeCardia
2022
Allium vegetables intake and the risk of gastric cancer in the Stomach cancer Pooling (StoP) Project
Dalmartello M, Turati F, Zhang ZF, Lunet N, Rota M, Bonzi R, Galeone C, Martimianaki G, Palli D, Ferraroni M, Yu GP, Morais S, Malekzadeh R, López-Carrillo L, Zaridze D, Maximovitch D, Aragonés N, Fernández-Tardón G, Martin V, Vioque J, Garcia de la Hera M, Curado MP, Coimbra FJF, Assumpcao P, Pakseresht M, Hu J, Hernández-Ramírez RU, Ward MH, Pourfarzi F, Mu L, Tsugane S, Hidaka A, Lagiou P, Lagiou A, Trichopoulou A, Karakatsani A, Boffetta P, Camargo MC, Negri E, La Vecchia C, Pelucchi C. Allium vegetables intake and the risk of gastric cancer in the Stomach cancer Pooling (StoP) Project. British Journal Of Cancer 2022, 126: 1755-1764. PMID: 35210588, PMCID: PMC9174191, DOI: 10.1038/s41416-022-01750-5.Peer-Reviewed Original ResearchConceptsStomach cancer Pooling (StoP) ProjectAllium vegetablesOdds ratioInverse associationPooling ProjectStudy-specific odds ratiosGC riskAllium vegetable intakePooled odds ratioGastric cancer riskIndividual participant dataHeterogeneity of resultsVegetable intakeGastric cancerHigh intakeCancer riskEpidemiological studiesGC casesParticipant dataStrong associationSubstantial heterogeneityRiskIntakeAssociationVegetables
2020
Polyphenol Intake and Gastric Cancer Risk: Findings from the Stomach Cancer Pooling Project (StoP)
Vitelli-Storelli F, Rossi M, Pelucchi C, Rota M, Palli D, Ferraroni M, Lunet N, Morais S, López-Carrillo L, Zaridze DG, Maximovich D, García M, Castaño-Vinyals G, Aragonés N, de la Hera M, Hernández-Ramírez RU, Negri E, Bonzi R, Ward MH, Lagiou A, Lagiou P, López-Cervantes M, Boffetta P, Camargo MC, Curado MP, Zhang ZF, Vioque J, La Vecchia C, Sánchez V. Polyphenol Intake and Gastric Cancer Risk: Findings from the Stomach Cancer Pooling Project (StoP). Cancers 2020, 12: 3064. PMID: 33092262, PMCID: PMC7588964, DOI: 10.3390/cancers12103064.Peer-Reviewed Original ResearchStomach cancer Pooling (StoP) ProjectGastric cancerInverse associationPooling ProjectStudy-specific ORsSuggestive inverse associationStrata of ageIntake of polyphenolsMultivariate logistic regressionGastric cancer riskIndividual participant dataRandom-effects modelSmoking habitsPolyphenol intakeCancer riskLogistic regressionCancer typesGC riskParticipant dataSpecific ORsFavorable effectConfidence intervalsPolyphenol classesEffects modelFurther investigation
2019
Education and gastric cancer risk—An individual participant data meta‐analysis in the StoP project consortium
Rota M, Alicandro G, Pelucchi C, Bonzi R, Bertuccio P, Hu J, Zhang Z, Johnson KC, Palli D, Ferraroni M, Yu G, Galeone C, López‐Carrillo L, Muscat J, Lunet N, Ferro A, Ye W, Plymoth A, Malekzadeh R, Zaridze D, Maximovitch D, Kogevinas M, de Larrea N, Vioque J, Navarrete‐Muñoz E, Tsugane S, Hamada GS, Hidaka A, Pakseresht M, Wolk A, Håkansson N, Hernández‐Ramírez R, López‐Cervantes M, Ward M, Pourfarzi F, Mu L, Kurtz RC, Lagiou A, Lagiou P, Boffetta P, Boccia S, Negri E, La Vecchia C. Education and gastric cancer risk—An individual participant data meta‐analysis in the StoP project consortium. International Journal Of Cancer 2019, 146: 671-681. PMID: 30919464, DOI: 10.1002/ijc.32298.Peer-Reviewed Original ResearchConceptsGastric cancer riskIndividual participant dataOdds ratioCancer riskSocioeconomic positionHighest household income categoryStomach cancer Pooling (StoP) ProjectStudy-specific odds ratiosH. pylori-negative subjectsGC riskParticipant dataPylori-negative subjectsStrong risk factorRandom-effects meta-analytic modelConfidence intervalsPooled odds ratioStrong inverse associationLow socioeconomic positionPublic health interventionsHousehold income categoryNegative subjectsInverse associationRisk factorsPooling ProjectPremature mortality
2014
Dietary Patterns and Gastric Cancer Risk in Mexico
Denova-Gutiérrez E, Hernández-Ramírez RU, López-Carrillo L. Dietary Patterns and Gastric Cancer Risk in Mexico. Nutrition And Cancer 2014, 66: 369-376. PMID: 24628363, DOI: 10.1080/01635581.2014.884237.Peer-Reviewed Original ResearchConceptsDietary patternsGastric cancerGC riskPopulation-based case-control studyLower GC riskMajor dietary patternsHealthy dietary patternCase-control studyMultiple epidemiological studiesGastric cancer riskConsumption of vegetablesExtreme quintilesHighest quintileLowest quintileCancer riskEpidemiological studiesFood groupsSignificant associationGC casesP-trendIndividual foodsQuintilePattern 1RiskWhite meat
2012
Capsaicin consumption, Helicobacter pylori CagA status and IL1B-31C>T genotypes: A host and environment interaction in gastric cancer
López-Carrillo L, Camargo MC, Schneider BG, Sicinschi LA, Hernández-Ramírez RU, Correa P, Cebrian ME. Capsaicin consumption, Helicobacter pylori CagA status and IL1B-31C>T genotypes: A host and environment interaction in gastric cancer. Food And Chemical Toxicology 2012, 50: 2118-2122. PMID: 22414649, PMCID: PMC3636974, DOI: 10.1016/j.fct.2012.02.043.Peer-Reviewed Original ResearchConceptsGastric cancerCagA statusHelicobacter pylori CagA statusGC riskH. pylori CagA statusConsumption of capsaicinFood frequency questionnaireUnconditional logistic regressionHigh-risk individualsVirulent H. pyloriFrequency questionnaireClinical controlGC patientsRisk individualsT genotypeGene-environment interactionsMortality ratePotential interactionsIL1B -31CH. pyloriSusceptible individualsMortality trendsCapsaicin consumptionLogistic regressionTaqMan assays
2009
Dietary intake of polyphenols, nitrate and nitrite and gastric cancer risk in Mexico City
Hernández‐Ramírez R, Galván‐Portillo M, Ward MH, Agudo A, González CA, Oñate‐Ocaña L, Herrera‐Goepfert R, Palma‐Coca O, López‐Carrillo L. Dietary intake of polyphenols, nitrate and nitrite and gastric cancer risk in Mexico City. International Journal Of Cancer 2009, 125: 1424-1430. PMID: 19449378, PMCID: PMC2787087, DOI: 10.1002/ijc.24454.Peer-Reviewed Original ResearchConceptsHigh intakeGastric cancerGC riskN-nitroso compoundsPopulation-based case-control studyFood frequency questionnaireIntake of polyphenolsCase-control studyGastric cancer riskPotent animal carcinogensFrequency questionnaireDietary intakeNitrite intakeLow intakeProtective effectCancer riskDietary polyphenolsEndogenous nitrosationTotal nitriteDiffuse typeCombined consumptionPotential human carcinogensGC casesNOC precursorsIntakeGastric cancer in relation to the intake of nutrients involved in one-carbon metabolism among MTHFR 677 TT carriers
Galván-Portillo MV, Cantoral A, Oñate-Ocaña LF, Chen J, Herrera-Goepfert R, Torres-Sanchez L, Hernandez-Ramirez RU, Palma-Coca O, López-Carrillo L. Gastric cancer in relation to the intake of nutrients involved in one-carbon metabolism among MTHFR 677 TT carriers. European Journal Of Nutrition 2009, 48: 269-276. PMID: 19288150, DOI: 10.1007/s00394-009-0010-5.Peer-Reviewed Original ResearchConceptsOne-carbon metabolismDNA methylationMTHFR 677 TT genotypeImportant epigenetic processDietary intakeTT genotypePopulation-based case-control studyGC riskMethylenetetrahydrofolate reductaseFood frequency questionnaireTranscriptional controlHuman genomeCase-control studySex-matched controlsEpigenetic processesPCR-RFLP analysisMTHFR 677 CCMTHFR 677 CBorderline of significanceKey enzymeIntake of nutrientsMetabolic pathwaysCancer initiationMethyl-donor nutrientsMethylation