Featured Publications
BRCA1–BARD1 promotes RAD51-mediated homologous DNA pairing
Zhao W, Steinfeld JB, Liang F, Chen X, Maranon DG, Jian Ma C, Kwon Y, Rao T, Wang W, Sheng C, Song X, Deng Y, Jimenez-Sainz J, Lu L, Jensen RB, Xiong Y, Kupfer GM, Wiese C, Greene EC, Sung P. BRCA1–BARD1 promotes RAD51-mediated homologous DNA pairing. Nature 2017, 550: 360-365. PMID: 28976962, PMCID: PMC5800781, DOI: 10.1038/nature24060.Peer-Reviewed Original ResearchAmino Acid SequenceBase PairingBRCA1 ProteinBRCA2 ProteinChromosome PairingFanconi Anemia Complementation Group N ProteinGenes, BRCA1Genes, BRCA2HumansMultiprotein ComplexesMutationProtein BindingRad51 RecombinaseRecombinational DNA RepairSequence Homology, Nucleic AcidTemplates, GeneticTumor Suppressor ProteinsUbiquitin-Protein Ligases
2023
BRCA2 chaperones RAD51 to single molecules of RPA-coated ssDNA
Bell J, Dombrowski C, Plank J, Jensen R, Kowalczykowski S. BRCA2 chaperones RAD51 to single molecules of RPA-coated ssDNA. Proceedings Of The National Academy Of Sciences Of The United States Of America 2023, 120: e2221971120. PMID: 36976771, PMCID: PMC10083600, DOI: 10.1073/pnas.2221971120.Peer-Reviewed Original Research