mRNA Helicase Activity of the Ribosome
Takyar S, Hickerson RP, Noller HF. mRNA Helicase Activity of the Ribosome. Cell 2005, 120: 49-58. PMID: 15652481, DOI: 10.1016/j.cell.2004.11.042.Peer-Reviewed Original ResearchConceptsHelicase activitySecondary structureHelicase active siteMutation of residuesVitro translation systemMRNA secondary structureDownstream mRNA secondary structureAbility of ribosomesDownstream helicesProtein S3Most mRNAsBase-paired helicesRibosomesTranslation systemHelixActive siteDisplacement assayDownstream tunnelHelicaseCodonProcessivitySubunitsMutationsMRNAResidues