2024
Prognostic Effect of Mismatch Repair Status in Early-Stage Endometrial Cancer Treated With Adjuvant Radiation: A Multi-institutional Analysis
Hathout L, Sherwani Z, Alegun J, Ohri N, Fields E, Shah S, Beriwal S, Horne Z, Kidd E, Leung E, Song J, Taunk N, Chino J, Huang C, Russo A, Dyer M, Li J, Albuquerque K, Damast S. Prognostic Effect of Mismatch Repair Status in Early-Stage Endometrial Cancer Treated With Adjuvant Radiation: A Multi-institutional Analysis. International Journal Of Radiation Oncology • Biology • Physics 2024, 119: 1158-1165. PMID: 38253292, DOI: 10.1016/j.ijrobp.2024.01.203.Peer-Reviewed Original ResearchRecurrence-free survivalEndometrioid endometrial adenocarcinomaMismatch repair statusAdjuvant radiation therapyOverall survivalRadiation therapyVaginal brachytherapyMismatch repair deficiencyAssociated with worse recurrence-free survivalMulti-institutional retrospective cohort studyTreated with adjuvant radiation therapyAssociated with recurrence-free survivalMultivariate analysisExternal beam radiation therapyRecurrence-free survival ratesMismatch repair deficiency statusBeam radiation therapyGrades 1 to 2Kaplan-Meier methodOutcomes of patientsMulti-institutional analysisRetrospective cohort studyCox proportional hazards modelsProportional hazards modelAdjuvant radiation
2021
Declining Use of Inguinofemoral Lymphadenectomy in the Treatment of Clinically Negative, Pathologic Node Positive Vulvar Cancer: A National Cancer Database Analysis
Mokhtech M, Gao S, Kassick M, Menderes G, Damast S. Declining Use of Inguinofemoral Lymphadenectomy in the Treatment of Clinically Negative, Pathologic Node Positive Vulvar Cancer: A National Cancer Database Analysis. International Journal Of Radiation Oncology • Biology • Physics 2021, 111: e636-e637. DOI: 10.1016/j.ijrobp.2021.07.1687.Peer-Reviewed Original ResearchSentinel lymph node biopsyNational Cancer DatabaseNode-positive vulvar cancerInguinofemoral lymphadenectomyVulvar cancerOverall survivalGroin diseaseUse of SLNBNational Cancer Database AnalysisProportional hazards regression modelingVulvar cancer patientsKaplan-Meier methodLymph node biopsyRate of patientsManagement of patientsLog-rank testInitial staging procedureLymph node dataSignificant differencesWilcoxon rank sum testMATERIAL/METHODSWarrants further studyRank sum testAdjuvant chemoradiationAdjuvant radiation