2023
Investigating the Relationship between the Dose to the Recto-Vaginal Reference Point and Vaginal Stenosis among Cervical Cancer Patients Treated at a North American Academic Institution
Adefres B, Wallington D, Tien C, Damast S. Investigating the Relationship between the Dose to the Recto-Vaginal Reference Point and Vaginal Stenosis among Cervical Cancer Patients Treated at a North American Academic Institution. International Journal Of Radiation Oncology • Biology • Physics 2023, 117: e501. DOI: 10.1016/j.ijrobp.2023.06.1746.Peer-Reviewed Original ResearchVaginal stenosisDose constraintsMedian doseMultivariable Cox proportional hazards regressionCox proportional hazards regressionCohort median ageAdvanced cervical cancerInterstitial needlesKaplan-Meier methodCervical cancer patientsProportional hazards regressionLog-rank testHR-CTV D90MATERIAL/METHODSImage-guided brachytherapyNorth American academic institutionsLACC patientsPrimary endpointCumulative incidenceOnly patientsPatient demographicsMedian ageCervical cancerCancer patientsSingle institution
2012
Comparative patient-centered outcomes (health state and adverse sexual symptoms) between adjuvant brachytherapy versus no adjuvant brachytherapy in early-stage endometrial cancer.
Damast S, Alektiar K, Goldfarb S, Gerber N, Eaton A, Patil S, Mosenkis J, Sit L, Rogak L, Leitao M, Carter J, Basch E. Comparative patient-centered outcomes (health state and adverse sexual symptoms) between adjuvant brachytherapy versus no adjuvant brachytherapy in early-stage endometrial cancer. Journal Of Clinical Oncology 2012, 30: 9104-9104. DOI: 10.1200/jco.2012.30.15_suppl.9104.Peer-Reviewed Original ResearchFemale Sexual Function IndexSimple hysterectomyPoor sexual functioningFSFI scoreEndometrial cancerSexual functioningAdjuvant brachytherapyExact testEarly-stage endometrial cancerHealth statesStage I endometrial cancerBaseline sexual activityMedian FSFI scorePatient-centered outcomesSexual Function IndexWorse sexual functioningFisher's exact testWaiver of consentTreatment-related itemsCross-sectional analysisPoor health statesCurrent sexual functioningHormonal therapyPrimary endpointAlone group