2021
Sex differences in progestogen- and androgen-derived neurosteroids in vulnerability to alcohol and stress-related disorders
Peltier MR, Verplaetse TL, Mineur YS, Gueorguieva R, Petrakis I, Cosgrove KP, Picciotto MR, McKee SA. Sex differences in progestogen- and androgen-derived neurosteroids in vulnerability to alcohol and stress-related disorders. Neuropharmacology 2021, 187: 108499. PMID: 33600842, PMCID: PMC7992136, DOI: 10.1016/j.neuropharm.2021.108499.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsConceptsStress-related disordersAlcohol useMajor depressive disorderAlcohol-related disordersAlcohol use disorderPosttraumatic stress disorderStress regulation systemComplex comorbiditiesDepressive disorderProblematic alcohol useUse disordersAlcohol misuseTherapeutic potentialTrauma exposureSubstance abuseStress disorderAnxiety disordersDisordersExposure resultsProgestogensNeurosteroidsNegative affectWomenComorbiditiesMale counterparts
2020
A Critical Review of Alcohol Administration Guidelines in Laboratory Medication Screening Research: Is It Time to Include Treatment Seekers?
Roberts W, Verplaetse TL, Ramchandani VA, McKee SA. A Critical Review of Alcohol Administration Guidelines in Laboratory Medication Screening Research: Is It Time to Include Treatment Seekers? Alcohol Clinical And Experimental Research 2020, 45: 15-24. PMID: 33190310, PMCID: PMC7855436, DOI: 10.1111/acer.14514.Peer-Reviewed Original ResearchMeSH KeywordsAdrenergic alpha-2 Receptor AgonistsAlcohol DeterrentsAlcohol-Related DisordersClinical Trials as TopicGuanfacineHumansNaltrexonePatient SelectionConceptsHuman laboratory studiesTreatment seekersNontreatment seekersExpensive clinical trialsPatient populationAlcohol administrationClinical trialsMedication effectsClinical conditionsMedication developmentMedicationsHeavy drinkersMedication experimentsLaboratory screeningClinical realityAdministration guidelinesScreening researchDevelopment pipelineLaboratory studiesRiskGuidelinesParticipantsPharmacotherapyPopulationEthical guidelines
2016
Effect of Varenicline Combined with High‐Dose Alcohol on Craving, Subjective Intoxication, Perceptual Motor Response, and Executive Cognitive Function in Adults with Alcohol Use Disorders: Preliminary Findings
Verplaetse TL, Pittman BP, Shi JM, Tetrault JM, Coppola S, McKee SA. Effect of Varenicline Combined with High‐Dose Alcohol on Craving, Subjective Intoxication, Perceptual Motor Response, and Executive Cognitive Function in Adults with Alcohol Use Disorders: Preliminary Findings. Alcohol Clinical And Experimental Research 2016, 40: 1567-1576. PMID: 27246567, PMCID: PMC4930423, DOI: 10.1111/acer.13110.Peer-Reviewed Original ResearchMeSH KeywordsAdultAlcohol-Related DisordersAlcoholic IntoxicationAssociation LearningBlood PressureCravingDose-Response Relationship, DrugDouble-Blind MethodEthanolExecutive FunctionFemaleHeart RateHumansMaleMemory, Short-TermNicotinic AgonistsPsychological TestsPsychomotor PerformanceVareniclineYoung AdultConceptsPerceptual-motor functionAlcohol use disorderExecutive cognitive functionCognitive functionDose of alcoholSubjective reactivitySubjective intoxicationHigh-dose alcoholNonalcoholic control beverageAlcohol-motivated behaviorsUse disordersEffects of vareniclineAssociative learningAversive eventsLaboratory paradigmDiastolic blood pressureAlcohol cravingControl beverageMotor responsePhysiologic reactivityAlcohol-related increasesLaboratory sessionsMotor functionBlood pressurePreliminary investigationEffect of Lowering the Dose of Varenicline on Alcohol Self-administration in Drinkers With Alcohol Use Disorders
Verplaetse TL, Pittman BP, Shi JM, Tetrault JM, Coppola S, McKee SA. Effect of Lowering the Dose of Varenicline on Alcohol Self-administration in Drinkers With Alcohol Use Disorders. Journal Of Addiction Medicine 2016, 10: 166-173. PMID: 27159341, PMCID: PMC4880525, DOI: 10.1097/adm.0000000000000208.Peer-Reviewed Original ResearchMeSH KeywordsAdultAlcohol-Related DisordersDose-Response Relationship, DrugDouble-Blind MethodFemaleHumansMaleMiddle AgedNicotinic AgonistsOutcome Assessment, Health CareVareniclineConceptsAlcohol use disorderEffects of vareniclineAlcohol consumptionUse disordersVarenicline doseD dosePlasma levelsDose of vareniclineDoses of vareniclineFrequency of insomniaPlacebo-controlled investigationHigher plasma levelsDose of alcoholAlcohol Self-AdministrationSelf-administration periodMedication pretreatmentAdverse eventsEdition criteriaVareniclineLow doseSide effectsAlcohol cravingMeeting criteriaPhysiologic responsesAlcohol-related outcomes
2015
Association of Cigarette Smoking With Interpersonal and Self-Directed Violence in a Large Community-Based Sample
Lewis AS, Oberleitner LM, Morgan PT, Picciotto MR, McKee SA. Association of Cigarette Smoking With Interpersonal and Self-Directed Violence in a Large Community-Based Sample. Nicotine & Tobacco Research 2015, 18: 1456-1462. PMID: 26718905, PMCID: PMC5942535, DOI: 10.1093/ntr/ntv287.Peer-Reviewed Original ResearchMeSH KeywordsAdultAlcohol-Related DisordersCigarette SmokingCross-Sectional StudiesFemaleHumansMaleMiddle AgedRisk FactorsTobacco Use DisorderViolenceConceptsCigarette smoking statusSmoking statusCigarette smokingSelf-directed violenceRisk factorsDaily smokersViolence risk assessmentWave 1Substance useFormer cigarette smokersFormer daily smokersDaily cigarette smokingMajor risk factorNational Epidemiological SurveyCommunity-based sampleLogistic regression modelsRelevant demographic covariatesViolence risk factorsCessation strategiesCigarette smokersPsychiatric diagnosisEpidemiological surveySmokersSmokingAdult subjects
2013
Changes in Smoking for Adults with and without Alcohol and Drug Use Disorders: Longitudinal Evaluation in the US Population
Weinberger AH, Pilver CE, Hoff RA, Mazure CM, McKee SA. Changes in Smoking for Adults with and without Alcohol and Drug Use Disorders: Longitudinal Evaluation in the US Population. The American Journal Of Drug And Alcohol Abuse 2013, 39: 186-193. PMID: 23721534, PMCID: PMC3696891, DOI: 10.3109/00952990.2013.785557.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultAlcohol-Related DisordersFemaleHumansLongitudinal StudiesMaleMiddle AgedRecurrenceSmokingSmoking CessationSubstance-Related DisordersUnited StatesYoung AdultConceptsCurrent drug use disordersDrug use disordersCurrent alcohol use disorderAlcohol use disorderDUD diagnosesUse disordersSmoking cessationDaily smokersSmoking relapsePast alcohol use disordersFormer daily smokersCurrent daily smokersUS adult populationDaily cigarette smokersAssessment 3 yearsNational Epidemiologic SurveyWave 2Gender-specific effectsCigarette smokersEpidemiologic SurveyDiagnosis interactionRelapse behaviorSmokingUS populationAdult population
2012
Smoke-free policies in drinking venues predict transitions in alcohol use disorders in a longitudinal U.S. sample
Young-Wolff KC, Hyland AJ, Desai R, Sindelar J, Pilver CE, McKee SA. Smoke-free policies in drinking venues predict transitions in alcohol use disorders in a longitudinal U.S. sample. Drug And Alcohol Dependence 2012, 128: 214-221. PMID: 22999418, PMCID: PMC4052952, DOI: 10.1016/j.drugalcdep.2012.08.028.Peer-Reviewed Original ResearchMeSH KeywordsAdultAge FactorsAlcohol-Related DisordersFemaleHumansLogistic ModelsLongitudinal StudiesMaleMiddle AgedProspective StudiesSex FactorsSmoke-Free PolicyUnited StatesConceptsAlcohol use disorderSmoke-free legislationSmoke-free policiesAUD remissionUse disordersLikelihood of AUDWave IIndoor public venuesLongitudinal U.S. sampleTobacco-related diseasesYounger age groupsNational Epidemiological SurveySmoke-free barsPublic health benefitsAUD onsetHigh comorbidityProtective effectCurrent drinkersTobacco useEpidemiological surveyAge groupsLogistic regressionRelated conditionsHeavy drinkingLower likelihood
2011
Non-daily smoking predicts hazardous drinking and alcohol use disorders in young adults in a longitudinal U.S. sample
Harrison EL, McKee SA. Non-daily smoking predicts hazardous drinking and alcohol use disorders in young adults in a longitudinal U.S. sample. Drug And Alcohol Dependence 2011, 118: 78-82. PMID: 21441000, PMCID: PMC3134579, DOI: 10.1016/j.drugalcdep.2011.02.022.Peer-Reviewed Original ResearchConceptsNon-daily smokingAlcohol use disorderNon-daily smokersUse disordersHazardous drinkingYoung adultsAlcohol useProblematic alcohol useLongitudinal U.S. sampleWave 1National Epidemiological SurveyWave 2Smoking statusAlcohol drinkingDaily smokingEarly treatmentDependence disordersSmokingAlcohol abuseSmoking behaviorEpidemiological surveyGreater riskRelated conditionsBeneficial effectsCross-sectional data
2008
Cigarette Smoking and Intimate Partner Violence Among Men Referred to Substance Abuse Treatment
Easton CJ, Weinberger AH, McKee SA. Cigarette Smoking and Intimate Partner Violence Among Men Referred to Substance Abuse Treatment. The American Journal Of Drug And Alcohol Abuse 2008, 34: 39-46. PMID: 18161642, DOI: 10.1080/00952990701522682.Peer-Reviewed Original ResearchConceptsCigarette smokingSubstance abuse treatmentDaily smokersIntimate partner violenceAbuse treatmentNon-daily smokersCurrent cigarette smokingDaily cigarette smokingAlcohol dependent offendersAlcohol-dependent menAntisocial personality disorderPartner violenceASI alcoholDependent menSmokersSmokingAlcohol useDependent offendersMore daysPersonality disorderMore participantsTreatmentMenDaysParticipants