Malignant Melanoma in Older Adults: Different Patient or Different Disease?
Sasson D, Smetona J, Parsaei Y, Papageorge M, Ariyan S, Olino K, Clune J. Malignant Melanoma in Older Adults: Different Patient or Different Disease? Cureus 2023, 15: e34742. PMID: 36909026, PMCID: PMC9998075, DOI: 10.7759/cureus.34742.Peer-Reviewed Original ResearchMelanoma-specific survivalRecurrence-free survivalOlder patientsT2 tumorsNodal positivityMetastatic progressionOlder adultsConclusion Older adultsLog-rank testingKaplan-Meier analysisT4 tumorsYounger patientsT1 tumorsBreslow thicknessClinical outcomesTumor characteristicsTumor thicknessSingle institutionClinical behaviorMalignant melanomaLower incidenceHigh incidencePatientsConsecutive sampleAge groupsPredictive accuracy of elevated mitotic rate on lymph node positivity and recurrence in thin melanomas
Ly C, Blaha O, Wei W, Galan A, Kluger H, Ariyan S, Olino K, Clune J. Predictive accuracy of elevated mitotic rate on lymph node positivity and recurrence in thin melanomas. Frontiers In Oncology 2023, 12: 1077226. PMID: 36686728, PMCID: PMC9853390, DOI: 10.3389/fonc.2022.1077226.Peer-Reviewed Original ResearchMelanoma-specific mortalityElevated mitotic rateLymph node positivityMitoses/Mitotic rateT2 tumorsNode positivityThin melanomasSentinel lymph node positivityImportant prognostic factorSingle academic centerPrimary cutaneous melanomaLow mitotic ratePositive SLNNon-ulcerated lesionsSLN biopsyT4 tumorsPatient demographicsPrognostic factorsSLN positivityRetrospective reviewTumor characteristicsBreslow thicknessCutaneous melanomaT category