2017
Using Cryo‐electron Microscopy to Discover Box C/D s(no)RNP Structure
Baserga S, Yip W, Shigematsu H, Taylor D. Using Cryo‐electron Microscopy to Discover Box C/D s(no)RNP Structure. The FASEB Journal 2017, 31 DOI: 10.1096/fasebj.31.1_supplement.910.2.Peer-Reviewed Original ResearchBox C/DArchaeal box C/D sRNPsBox C/D sRNAsBox C/D sRNPRibosomal RNA modificationsElectron microscopy modelCryo-electron microscopyCryo-EM reconstructionCellular organismsRRNA modificationRibosome functionRNA modificationsSRNAsSRNPStructural techniquesEukaryaPotential interactionsArchaeaStructural analysisStem endClose proximityOrganismsNuclear magnetic resonance studiesStemInteraction
2016
Box C/D sRNA stem ends act as stabilizing anchors for box C/D di-sRNPs
Yip WS, Shigematsu H, Taylor DW, Baserga SJ. Box C/D sRNA stem ends act as stabilizing anchors for box C/D di-sRNPs. Nucleic Acids Research 2016, 44: 8976-8989. PMID: 27342279, PMCID: PMC5062973, DOI: 10.1093/nar/gkw576.Peer-Reviewed Original ResearchConceptsBox C/DArchaeal box C/D sRNPsBox C/D sRNAsBox C/D sRNPRibosomal RNA modificationsElectron microscopy modelCryo-EM reconstructionCellular organismsRibosome functionRNA modificationsSRNAsSRNPModification typesStructural techniquesEukaryaPotential interactionsStemArchaeaStructural analysisStem endClose proximityOrganismsNuclear magnetic resonance studiesCatalyseInteraction
2012
The Box C/D sRNP dimeric architecture is conserved across Kingdom Archaea
Baserga S, Phipps K, Taylor D, Wang H. The Box C/D sRNP dimeric architecture is conserved across Kingdom Archaea. The FASEB Journal 2012, 26: 773.2-773.2. DOI: 10.1096/fasebj.26.1_supplement.773.2.Peer-Reviewed Original ResearchBox C/D sRNPDimeric architectureBox C/DRecent structural studiesSRNP assemblyArchaeal speciesArchaeal kingdomOligomeric architectureKingdom ArchaeaPyrococcus abyssiArchaeoglobus fulgidusMutational analysisSRNPSingle-particle reconstructionStructural determinantsArchaeaStructural studiesEukaryotesSRNAsFulgidusSolfataricusParticle reconstructionRNASpeciesMutations