2024
Effect of endoscopic ultrasound guided celiac plexus block on the palliation of pain in chronic pancreatitis (EPOCH Trial): study protocol for a randomized multicenter sham-controlled trial {1}
Wilcox C, Bang J, Buxbaum J, Gardner T, Hawes R, Kedia P, Mardini S, Muniraj T, Navaneethan U, Oza V, Tarnasky P, Thakkar S, Waxman I, Varadarajulu S. Effect of endoscopic ultrasound guided celiac plexus block on the palliation of pain in chronic pancreatitis (EPOCH Trial): study protocol for a randomized multicenter sham-controlled trial {1}. Trials 2024, 25: 676. PMID: 39396987, PMCID: PMC11472533, DOI: 10.1186/s13063-024-08478-y.Peer-Reviewed Original ResearchMeSH KeywordsAbdominal PainAutonomic Nerve BlockCeliac PlexusEndosonographyHumansMulticenter Studies as TopicNerve BlockPain MeasurementPalliative CarePancreatitis, ChronicProspective StudiesRandomized Controlled Trials as TopicTime FactorsTreatment OutcomeUltrasonography, InterventionalUnited StatesConceptsCeliac plexus blockAbdominal painChronic pancreatitisVisual analog scalePlexus blockSham-controlled trialRandomized sham-controlled trialEndoscopic ultrasound-guided celiac plexus blockEffectiveness of endoscopic ultrasoundBrief Pain Inventory Short FormDocumented chronic pancreatitisPainful chronic pancreatitisPalliation of painTime of EUSTreatment of abdominal painPain scoresBPI-SFSteroid combinationsAnalog scaleEndoscopic ultrasoundProspective studyCeliac plexusRandomized trialsShort formPancreatitis
2023
Outcomes of cold snare EMR of nonampullary duodenal adenomas ≥1 cm: a multicenter study
Wilson N, Abdallah M, Schulman A, Mosko J, Saeed A, Kothari S, Kaul V, Kothari T, Phan J, Kumar A, Tofani C, Kim R, Westanmo A, Moy B, Dang F, Canakis A, Sharma N, Muniraj T, Azeem N, Bilal M. Outcomes of cold snare EMR of nonampullary duodenal adenomas ≥1 cm: a multicenter study. Gastrointestinal Endoscopy 2023, 99: 971-980.e1. PMID: 38092125, DOI: 10.1016/j.gie.2023.12.007.Peer-Reviewed Original ResearchNonampullary duodenal adenomasEndoscopic mucosal resectionCold snare endoscopic mucosal resectionSnare endoscopic mucosal resectionDuodenal adenomasUse of electrocauteryAdverse eventsMucosal resectionMulticenter studyUnderwater endoscopic mucosal resectionLarge duodenal adenomasMulticenter retrospective studyRetrospective multicenter studyPredictors of recurrenceAcceptable recurrence rateHigh-grade dysplasiaFuture prospective studiesCases of perforationAdenoma rateSecondary outcomesImmediate bleedingPrimary outcomeRecurrent adenomasIndependent predictorsProspective study
2020
Differences in Age at Onset of Symptoms, and Effects of Genetic Variants, in Patients With Early vs Late-Onset Idiopathic Chronic Pancreatitis in a North American Cohort
Lewis MD, Talluri J, Wilcox CM, Abberbock JN, Tang G, Conwell DL, Banks PA, Cote GA, Sherman S, Alkaade S, Gardner TB, Anderson MA, Sandhu BS, Muniraj T, Forsmark CE, Guda N, Gelrud A, Romagnuolo J, Brand R, LaRusch J, Amann ST, Slivka A, Whitcomb DC, Yadav D. Differences in Age at Onset of Symptoms, and Effects of Genetic Variants, in Patients With Early vs Late-Onset Idiopathic Chronic Pancreatitis in a North American Cohort. Clinical Gastroenterology And Hepatology 2020, 19: 349-357. PMID: 32240833, PMCID: PMC7529676, DOI: 10.1016/j.cgh.2020.03.047.Peer-Reviewed Original ResearchConceptsOnset of symptomsModerate alcohol drinkersNorth American cohortAlcohol drinkersAge of onsetAmerican cohortAlcohol useChronic pancreatitisClinical featuresLate-onset idiopathic chronic pancreatitisNorth American Pancreatitis Study 2Genetic variantsEarly-onset ICPLate-onset ICPQuarter of patientsHalf of patientsIdiopathic chronic pancreatitisHigher proportionHeavy alcohol useCross-sectional analysisICP symptomsConstant painMedian ageAvailable patientsProspective study
2019
Genetic Risk Score in Diabetes Associated With Chronic Pancreatitis Versus Type 2 Diabetes Mellitus
Goodarzi MO, Nagpal T, Greer P, Cui J, Chen YI, Guo X, Pankow JS, Rotter JI, Alkaade S, Amann ST, Baillie J, Banks PA, Brand RE, Conwell DL, Cote GA, Forsmark CE, Gardner TB, Gelrud A, Guda N, LaRusch J, Lewis MD, Money ME, Muniraj T, Papachristou GI, Romagnuolo J, Sandhu BS, Sherman S, Singh VK, Wilcox CM, Pandol SJ, Park WG, Andersen DK, Bellin MD, Hart PA, Yadav D, Whitcomb DC. Genetic Risk Score in Diabetes Associated With Chronic Pancreatitis Versus Type 2 Diabetes Mellitus. Clinical And Translational Gastroenterology 2019, 10: e00057. PMID: 31232720, PMCID: PMC6708663, DOI: 10.14309/ctg.0000000000000057.Peer-Reviewed Original ResearchConceptsGenetic risk scoreDiabetes mellitusChronic pancreatitisCP-DMPancreatogenic diabetesRisk scoreNorth American Pancreatitis Study 2Type 2 diabetes mellitusLarge prospective studiesSingle nucleotide polymorphismsMulti-Ethnic StudyWeighted genetic risk scoreMean genetic risk scoreDiabetic groupNondiabetic controlsProspective studyNucleotide polymorphismsPathophysiologic entityFamily historyT2DMDiabetesType 2Separate disordersGold standardMellitus
2015
Cold Snare Polypectomy for Large Sessile Colonic Polyps: A Single‐Center Experience
Muniraj T, Sahakian A, Ciarleglio MM, Deng Y, Aslanian HR. Cold Snare Polypectomy for Large Sessile Colonic Polyps: A Single‐Center Experience. Gastroenterology Research And Practice 2015, 2015: 175959. PMID: 25878658, PMCID: PMC4387686, DOI: 10.1155/2015/175959.Peer-Reviewed Original ResearchCold snare polypectomySnare polypectomySessile polypsLarge sessile colonic polypsSingle-center experienceFurther prospective studiesLarge sessile polypsLarger patient groupsSessile colonic polypsAdverse eventsPostpolypectomy bleedingComplication rateConventional polypectomyFavorable efficacyColonoscopic polypectomyPatient groupProspective studyColorectal cancerResidual polypProcedure timePolypectomyLarge polypsColonic polypsSmall polypsPolyps