Titus Boggon, PhD
Associate Professor of Pharmacology and of Molecular Biophysics and Biochemistry
Research & Publications
Biography
Locations
Research Summary
Cellular signaling cascades that control cytoskeletal remodeling, adhesion, and migration, are critical to life. The Boggon lab uses structural biology and associated techniques to define the molecular level details that control these pathways.
For up-to-date research and publication information click through to the lab website: www.boggonlab.org
Coauthors
Selected Publications
- 120 Treatable Acute Neuroinflammatory Disease Associated with Complement Factor I Loss-of-function in the Plain CommunityReid W, Carson V, Krieger P, Stiegler A, Boggon T, Sullivan K, van den Heuvel L, Romberg N. 120 Treatable Acute Neuroinflammatory Disease Associated with Complement Factor I Loss-of-function in the Plain Community. Clinical Immunology 2024, 262: 110062. DOI: 10.1016/j.clim.2024.110062.
- Abstract 1424 Distinct functional constraints driving conservation of the cofilin N-terminal regulatory tailPotchernikov A, Sexton J, Bibeau J, Lou H, Casanova G, Cao W, Boggon T, De La Cruz E, Turk B. Abstract 1424 Distinct functional constraints driving conservation of the cofilin N-terminal regulatory tail. Journal Of Biological Chemistry 2024, 300: 106897. DOI: 10.1016/j.jbc.2024.106897.
- Distinct functional constraints driving conservation of the cofilin N-terminal regulatory tailSexton J, Potchernikov T, Bibeau J, Casanova-Sepúlveda G, Cao W, Lou H, Boggon T, De La Cruz E, Turk B. Distinct functional constraints driving conservation of the cofilin N-terminal regulatory tail. Nature Communications 2024, 15: 1426. PMID: 38365893, PMCID: PMC10873347, DOI: 10.1038/s41467-024-45878-9.
- Autoregulation of the LIM kinases by their PDZ domainCasanova-Sepúlveda G, Sexton J, Turk B, Boggon T. Autoregulation of the LIM kinases by their PDZ domain. Nature Communications 2023, 14: 8441. PMID: 38114480, PMCID: PMC10730565, DOI: 10.1038/s41467-023-44148-4.
- Partial improvement of crystal quality for microgravity-grown apocrustacyanin C1.Snell E, Cassetta A, Helliwell J, Boggon T, Chayen N, Weckert E, Holzer K, Schroer K, Gordon E, Zagalsky P. Partial improvement of crystal quality for microgravity-grown apocrustacyanin C1. Acta Crystallographica Section D, Structural Biology 1997, 53: 231-9. PMID: 11540431.