2014
Clinical cancer research: the past, present and the future
DeVita VT, Eggermont AM, Hellman S, Kerr DJ. Clinical cancer research: the past, present and the future. Nature Reviews Clinical Oncology 2014, 11: 663-669. PMID: 25245981, DOI: 10.1038/nrclinonc.2014.153.Peer-Reviewed Original ResearchTreatment of Hodgkin Lymphoma: A 50-Year Perspective
Canellos GP, Rosenberg SA, Friedberg JW, Lister TA, DeVita VT. Treatment of Hodgkin Lymphoma: A 50-Year Perspective. Journal Of Clinical Oncology 2014, 32: 163-168. PMID: 24441526, DOI: 10.1200/jco.2013.53.1194.Peer-Reviewed Original ResearchAntineoplastic Combined Chemotherapy ProtocolsBiomarkers, TumorBleomycinClinical Trials as TopicCyclophosphamideDacarbazineDisease-Free SurvivalDoxorubicinEtoposideEuropeHistory, 20th CenturyHodgkin DiseaseHumansMechlorethamineNeoplasm StagingPositron-Emission TomographyPrednisoneProcarbazineSurvival RateTomography, X-Ray ComputedTreatment OutcomeVinblastineVincristine
2009
We have met the enemy and he is us!
DeVita V. We have met the enemy and he is us! Nature Reviews Clinical Oncology 2009, 6: 493-493. PMID: 19707237, DOI: 10.1038/nrclinonc.2009.89.Peer-Reviewed Original ResearchClinical Trials as TopicHumansNational Cancer Institute (U.S.)Practice Guidelines as TopicUnited StatesOff-label use of approved drugs
DeVita V. Off-label use of approved drugs. Nature Reviews Clinical Oncology 2009, 6: 181-181. PMID: 19333219, DOI: 10.1038/nrclinonc.2009.41.Peer-Reviewed Original Research
2008
The clinical trials system is broken
DeVita V. The clinical trials system is broken. Nature Reviews Clinical Oncology 2008, 5: 683-683. PMID: 19034294, DOI: 10.1038/ncponc1263.Peer-Reviewed Original ResearchThe era of personalized medicine: back to basics
Hutchinson L, DeVita V. The era of personalized medicine: back to basics. Nature Reviews Clinical Oncology 2008, 5: 623-623. PMID: 18957968, DOI: 10.1038/ncponc1253.Peer-Reviewed Original ResearchAntibodies, MonoclonalAntibodies, Monoclonal, HumanizedAntineoplastic AgentsAntineoplastic Combined Chemotherapy ProtocolsBenzamidesBiomarkers, TumorCarcinoma, Non-Small-Cell LungCetuximabClinical Trials as TopicColorectal NeoplasmsDrug Delivery SystemsDrug Resistance, NeoplasmGene TargetingGenes, erbB-1HumansImatinib MesylateLeukemia, Myelogenous, Chronic, BCR-ABL PositiveLung NeoplasmsPanitumumabPatient-Centered CarePiperazinesPyrimidinesTreatment OutcomeMore on strong inference
DeVita V. More on strong inference. Nature Reviews Clinical Oncology 2008, 5: 239-239. PMID: 18437157, DOI: 10.1038/ncponc1126.Peer-Reviewed Original Research
2007
The Provenge® decision
DeVita V. The Provenge® decision. Nature Reviews Clinical Oncology 2007, 4: 381-381. PMID: 17554239, DOI: 10.1038/ncponc0854.Peer-Reviewed Original Research
2005
Should the FDA be the doctor of last resort?
DeVita V. Should the FDA be the doctor of last resort? Nature Reviews Clinical Oncology 2005, 2: 423-423. PMID: 16264991, DOI: 10.1038/ncponc0292.Peer-Reviewed Original ResearchThe curse of the cure
DeVita V. The curse of the cure. Nature Reviews Clinical Oncology 2005, 2: 1-1. PMID: 16264829, DOI: 10.1038/ncponc0054.Peer-Reviewed Original Research
1999
Hodgkin's disease and transplantation: a room with a (nontransplanter's) view.
Marshall N, DeVita V. Hodgkin's disease and transplantation: a room with a (nontransplanter's) view. Seminars In Oncology 1999, 26: 67-73. PMID: 10073563.Peer-Reviewed Original ResearchConceptsHigh-dose chemotherapyPeripheral blood stem-cellHodgkin's diseaseOverall survivalRefractory diseaseDisease-freeBone marrowPeripheral blood stem-cell supportGraft-versus-host disease prophylaxisManagement of refractory diseasePatients potential candidatesImprove disease-freePatients disease-freeFollow-up timeShort follow-up timeResponse to treatmentSalvage chemotherapyApproach to treatmentCombination chemotherapyDose intensityTransplant supportAllograft patientsInitial remissionRelapse rateDisease prophylaxis
1993
Dose Intensity
SURBONE A, DeVITA V. Dose Intensity. Annals Of The New York Academy Of Sciences 1993, 698: 279-288. PMID: 8279768, DOI: 10.1111/j.1749-6632.1993.tb17219.x.Peer-Reviewed Original Research
1991
The influence of information on drug resistance on protocol design The Henry Kaplan Memorial Lecture, International Conference on Mulignant Lymphomas, 6–9 June 1990, Lugano, Switzerland
DeVita V. The influence of information on drug resistance on protocol design The Henry Kaplan Memorial Lecture, International Conference on Mulignant Lymphomas, 6–9 June 1990, Lugano, Switzerland. Annals Of Oncology 1991, 2: 93-106. PMID: 2054322, DOI: 10.1093/oxfordjournals.annonc.a057892.Peer-Reviewed Original Research
1989
NCI's breast cancer clinical alert: rationale and results.
DeVita V, Hubbard S. NCI's breast cancer clinical alert: rationale and results. Resident & Staff Physician 1989, 35: 49-55. PMID: 10303742.Peer-Reviewed Original ResearchMeSH KeywordsBreast NeoplasmsClinical Trials as TopicDiffusion of InnovationFemaleHumansInformation SystemsMEDLARSNational Institutes of Health (U.S.)United States
1987
The Emergence of Biologicals as Cancer Treatment: The Good News and The Bad
Devita V, Roper M. The Emergence of Biologicals as Cancer Treatment: The Good News and The Bad. Hospital Practice 1987, 22: 15-21. PMID: 3100560, DOI: 10.1080/21548331.1987.11707666.Peer-Reviewed Original Research
1986
Twenty years of MOPP therapy for Hodgkin's disease.
Longo D, Young R, Wesley M, Hubbard S, Duffey P, Jaffe E, DeVita V. Twenty years of MOPP therapy for Hodgkin's disease. Journal Of Clinical Oncology 1986, 4: 1295-306. PMID: 3528400, DOI: 10.1200/jco.1986.4.9.1295.Peer-Reviewed Original ResearchConceptsEnd of treatmentHodgkin's diseaseComplete responseDisease patientsLymphocyte-depleted typeHodgkin's disease patientsHigher CR rateResults of treatmentMOPP therapyB symptomsIntercurrent illnessComplete remissionLonger remissionsCR rateHodgkin's lymphomaLonger survivalBiopsy specimensPatientsHigh dosesDiseaseRemissionLymphomaMore cyclesTreatmentLarge cellsDose-response is alive and well.
DeVita V. Dose-response is alive and well. Journal Of Clinical Oncology 1986, 4: 1157-9. PMID: 3525764, DOI: 10.1200/jco.1986.4.8.1157.Peer-Reviewed Original ResearchThe effect of combined modality therapy on local control and survival
DeVita V, Lippman M, Hubbard S, Ihde D, Rosenberg S. The effect of combined modality therapy on local control and survival. International Journal Of Radiation Oncology • Biology • Physics 1986, 12: 487-501. PMID: 3009367, DOI: 10.1016/0360-3016(86)90056-8.Peer-Reviewed Original ResearchMeSH KeywordsAntineoplastic Combined Chemotherapy ProtocolsAnus NeoplasmsBreast NeoplasmsCarcinoma, Small CellClinical Trials as TopicCombined Modality TherapyFemaleHumansKidney NeoplasmsLung NeoplasmsLymphomaNeoplasm MetastasisNeoplasm Recurrence, LocalNeoplasmsPrognosisSarcomaSoft Tissue NeoplasmsWilms TumorConceptsLocal controlSystemic treatmentTumor typesPresence of micrometastasesEffective systemic therapyTumor cell numberLocal control measuresModality therapySystemic therapyCommon cancerMetastatic cancerLESS surgeryRadiation therapyTherapeutic programMetastatic processMicrometastasesTherapySurvivalSystemic componentCell numberTumorsMetastasis genesCancerSubstantial numberInverse relationship
1985
What are clinical trials all about?
DeVita V. What are clinical trials all about? Journal Of Pediatric Hematology/Oncology Nursing 1985, 2: 36. PMID: 3908649.Peer-Reviewed Original Research
1984
BCVPP chemotherapy for advanced Hodgkin's disease: evidence for greater duration of complete remission, greater survival, and less toxicity than with a MOPP regimen. Results of the Eastern Cooperative Oncology Group study.
Bakemeier R, Anderson J, Costello W, Rosner G, Horton J, Glick J, Hines J, Berard C, DeVita V. BCVPP chemotherapy for advanced Hodgkin's disease: evidence for greater duration of complete remission, greater survival, and less toxicity than with a MOPP regimen. Results of the Eastern Cooperative Oncology Group study. Annals Of Internal Medicine 1984, 101: 447-56. PMID: 6089632, DOI: 10.7326/0003-4819-101-4-447.Peer-Reviewed Original ResearchMeSH KeywordsAdultAntineoplastic Combined Chemotherapy ProtocolsBlood Cell CountCarmustineClinical Trials as TopicCombined Modality TherapyCyclophosphamideFemaleGastrointestinal DiseasesHematologic DiseasesHodgkin DiseaseHumansMaleMechlorethamineNeoplasm StagingPeripheral Nervous System DiseasesPrednisoneProcarbazineRandom AllocationVinblastineVincristineConceptsAdvanced Hodgkin's diseaseHodgkin's diseaseUntreated patientsEastern Cooperative Oncology Group studyDuration of complete remissionRandomized prospective studyTreatment of patientsMOPP regimenHematologic toxicityInduction chemotherapyComplete remissionChemotherapy regimensRemission rateNeurological toxicityProspective studyMOPPRemissionTherapeutic benefitChemotherapyPatientsInduction phaseDiseaseToxicityGroup studyDuration