2024
Male Robot-Assisted Radical Cystectomy with Nerve Sparing Technique
Tan W, Ta A, Sridhar A, Kelly J. Male Robot-Assisted Radical Cystectomy with Nerve Sparing Technique. 2024, 291-302. DOI: 10.1007/978-3-031-49428-4_23.Peer-Reviewed Original Research
2022
Robotic Intracorporeal Neobladder: UCLH Experience
Weyne E, Tan W, Kelly J, Sridhar A. Robotic Intracorporeal Neobladder: UCLH Experience. 2022, 681-686. DOI: 10.1007/978-3-031-00363-9_60.Peer-Reviewed Original ResearchRobot-assisted radical cystectomyUniversity College London HospitalRadical cystectomyBladder cancerHigh-risk non-muscle-invasive bladder cancerTreatment of muscle-invasive bladder cancerNon-muscle-invasive bladder cancerMuscle-invasive bladder cancerRobotic radical cystectomyOrthotopic continent diversionPatient selectionContinent diversionCystectomyPostoperative careOperative techniqueNeobladder
2021
Current application of the enhanced recovery after surgery protocol for patients undergoing radical cystectomy: lessons learned from European excellence centers
Albisinni S, Moschini M, Di Trapani E, Soria F, Mari A, Aziz A, Teoh J, Laukhtina E, Mori K, D’Andrea D, Carrion D, Krajewski W, Abufaraj M, Cimadamore A, Tan W, Flippot R, Khalifa J, Gonsette K, Pradere B. Current application of the enhanced recovery after surgery protocol for patients undergoing radical cystectomy: lessons learned from European excellence centers. World Journal Of Urology 2021, 40: 1317-1323. PMID: 34076754, DOI: 10.1007/s00345-021-03746-x.Peer-Reviewed Original ResearchConceptsOpioid-sparing anesthesiaRadical cystectomyERAS implementationPreoperative carbohydrate loadingEuropean expert centersImplementation of ERASBowel preparationERAS itemsRC patientsSurgery protocolExpert centersNasogastric tubeEarly mobilizationCarbohydrate loadingImplementing ERASEligibility criteriaCystectomyEnhanced recoverySurgeonsSurgeryAnesthesiologistsPatientsAnesthesiaERAS SocietyExcellence centersIs delay to radical cystectomy following BCG failure oncologically safe?
Tan W, Kelly J. Is delay to radical cystectomy following BCG failure oncologically safe? Nature Reviews Urology 2021, 18: 323-324. PMID: 33772157, DOI: 10.1038/s41585-021-00457-1.Peer-Reviewed Original Research
2020
Delayed blood transfusion is associated with mortality following radical cystectomy
Tan W, Wang Y, Trinh Q, Preston M, Kelly J, Hrouda D, Kibel A, Krasnow R, Liu J, Chung B, Chang S, Mossanen M. Delayed blood transfusion is associated with mortality following radical cystectomy. Scandinavian Journal Of Urology 2020, 54: 290-296. PMID: 32538224, DOI: 10.1080/21681805.2020.1777195.Peer-Reviewed Original ResearchConceptsDelayed blood transfusionEarly blood transfusionBlood transfusionRadical cystectomyBladder cancer treated with radical cystectomyPatients treated with radical cystectomyAssociated with 90-day mortalityIncreased 90-day mortalityTime of blood transfusionPrimary end pointRetrospective cohort studyMultivariate logistic regressionAssociated with mortalityDelayed transfusionMedian ageClinical deteriorationCystectomyHigher CCIOlder patientsTransfusionCohort studyEnd pointsPatient mortalityPatientsIndex admission
2019
Differences in trends in the use of robot‐assisted and open radical cystectomy and changes over time in peri‐operative outcomes among selected centres in North America and Europe: an international multicentre collaboration
Zamboni S, Soria F, Mathieu R, Xylinas E, Abufaraj M, D`Andrea D, Tan W, Kelly J, Simone G, Gallucci M, Meraney A, Krishna S, Konety B, Antonelli A, Simeone C, Baumeister P, Mattei A, Briganti A, Gallina A, Montorsi F, Rink M, Aziz A, Karakiewicz P, Rouprêt M, Koupparis A, Scherr D, Ploussard G, Sooriakumaran P, Shariat S, Moschini M, Urologists U. Differences in trends in the use of robot‐assisted and open radical cystectomy and changes over time in peri‐operative outcomes among selected centres in North America and Europe: an international multicentre collaboration. BJU International 2019, 124: 656-664. PMID: 31055865, DOI: 10.1111/bju.14791.Peer-Reviewed Original ResearchRobot-assisted radical cystectomyOpen radical cystectomyPeri-operative outcomesRadical cystectomyNorth American centresContemporary patientsPatients treated with open radical cystectomyEuropean centresPatients treated with robot-assisted radical cystectomyLower American Society of Anesthesiologists scoresAmerican Society of Anesthesiologists scoreLower blood lossRe-operation rateAmerican centresInternational multicentre collaborationContemporary seriesT stageBlood lossEarly complicationsRe-operationAnesthesiologists scoreBladder cancerGroup patientsRetrospective evaluationCystectomyExamining the relationship between complications and perioperative mortality following radical cystectomy: a population‐based analysis
Mossanen M, Krasnow R, Zlatev D, Tan W, Preston M, Trinh Q, Kibel A, Sonpavde G, Schrag D, Chung B, Chang S. Examining the relationship between complications and perioperative mortality following radical cystectomy: a population‐based analysis. BJU International 2019, 124: 40-46. PMID: 30499636, DOI: 10.1111/bju.14636.Peer-Reviewed Original ResearchConceptsRadical cystectomyPerioperative mortalityPostoperative mortalityIncidence of perioperative complicationsTreated with RCPremier Healthcare DatabaseNature of complicationsIncreasing predicted probabilityOdds of mortalityProbability of mortalityReadmission complicationsRenal-relatedSurgical characteristicsPerioperative complicationsBladder cancerPrimary outcomeComplicationsHealthcare databasesPatientsMortalityCystectomyMultivariate regressionReadmissionHospitalisationHospital
2018
Is experience with extracorporeal urinary diversion following robotic assisted radical cystectomy necessary before transitioning to intracorporeal urinary diversion?
Tan W, Kelly J. Is experience with extracorporeal urinary diversion following robotic assisted radical cystectomy necessary before transitioning to intracorporeal urinary diversion? Translational Andrology And Urology 2018, 0: s735-s737. PMID: 30687611, PMCID: PMC6323277, DOI: 10.21037/tau.2018.08.22.Peer-Reviewed Original Research
2017
Outcomes of Intracorporeal Urinary Diversion after Robot-Assisted Radical Cystectomy: Results from the International Robotic Cystectomy Consortium
Hussein A, May P, Jing Z, Ahmed Y, Wijburg C, Canda A, Dasgupta P, Khan M, Menon M, Peabody J, Hosseini A, Kelly J, Mottrie A, Kaouk J, Hemal A, Wiklund P, Guru K, Collaborators, Wagner A, Saar M, Stockle M, Redorta J, Richstone L, Badani K, Scherr D, Khan H, Gaboardi F, Rha K, Kawa O, Tan W, Schanne F, Polakis V, Weizer A, Maatman T, Pini G, Peak T, Kibel A, Yuh B. Outcomes of Intracorporeal Urinary Diversion after Robot-Assisted Radical Cystectomy: Results from the International Robotic Cystectomy Consortium. Journal Of Urology 2017, 199: 1302-1311. PMID: 29275112, DOI: 10.1016/j.juro.2017.12.045.Peer-Reviewed Original ResearchMeSH KeywordsAgedCystectomyFemaleHumansInternational CooperationMaleMiddle AgedOperative TimeOutcome and Process Assessment, Health CarePatient ReadmissionPostoperative ComplicationsProspective StudiesRetrospective StudiesRisk FactorsRobotic Surgical ProceduresTreatment OutcomeUrinary BladderUrinary Bladder NeoplasmsUrinary DiversionConceptsRobot-assisted radical cystectomyIntracorporeal urinary diversionExtracorporeal urinary diversionShorter operative timeRadical cystectomyHigh grade complicationsUrinary diversionOperative timeGrade complicationsInternational Robotic Cystectomy Consortium databaseInternational Robotic Cystectomy ConsortiumCompare perioperative outcomesLess blood lossMultivariate logistic regression modelPostoperative predictorsBlood lossPerioperative outcomesBlood transfusionCystectomy volumeCystectomyLogistic regression modelsComplicationsConsortium databaseMulti-institutionalPatientsMale Robot-Assisted Radical Cystectomy
Tan W, Sridhar A, Kelly J. Male Robot-Assisted Radical Cystectomy. 2017, 195-205. DOI: 10.1007/978-3-319-65864-3_16.Peer-Reviewed Original ResearchNon-muscle invasive bladder cancerMuscle invasive bladder cancerInvasive bladder cancerRadical cystectomyBladder cancerCohort of patientsMinimally invasive cystectomyExposure to environmental carcinogensPerioperative complicationsRecommended treatmentCystectomyCystectomy operationsTobacco smokeEnvironmental carcinogensThe Role of Robotics in the Invasive Management of Bladder Cancer
Khetrapal P, Tan W, Lamb B, Tan M, Baker H, Thompson J, Sridhar A, Kelly J, Briggs T. The Role of Robotics in the Invasive Management of Bladder Cancer. Current Urology Reports 2017, 18: 57. PMID: 28634646, DOI: 10.1007/s11934-017-0706-7.Peer-Reviewed Original ResearchConceptsRobot-assisted radical cystectomyRobot-assisted laparoscopic prostatectomyRadical cystectomyUrinary reconstructionIntracorporeal robot-assisted radical cystectomyManagement of bladder cancerOpen radical cystectomySurgical learning curveBladder cancer surgeryEnhanced recovery programmeComparison of outcomesLaparoscopic prostatectomyOncological outcomesIleus ratesBladder cancerCancer surgeryPerioperative measuresOpen techniqueInvasive managementShort recovery periodRobotic approachImprove outcomesPatient outcomesReduce recovery timeCystectomy
2016
Early Oncologic Failure after Robot-Assisted Radical Cystectomy: Results from the International Robotic Cystectomy Consortium
Hussein A, Saar M, May P, Wijburg C, Richstone L, Wagner A, Wilson T, Yuh B, Redorta J, Dasgupta P, Khan M, Menon M, Peabody J, Hosseini A, Gaboardi F, Mottrie A, Rha K, Hemal A, Stockle M, Kelly J, Maatman T, Canda A, Wiklund P, Guru K, Collaborators, Balbay M, Poulakis V, Woods M, Tan W, Kawa O, Pini G, Badani K, Ahmed Y. Early Oncologic Failure after Robot-Assisted Radical Cystectomy: Results from the International Robotic Cystectomy Consortium. Journal Of Urology 2016, 197: 1427-1436. PMID: 27993668, DOI: 10.1016/j.juro.2016.12.048.Peer-Reviewed Original ResearchConceptsRobot-assisted radical cystectomyOncological failureRadical cystectomyOverall survivalDisease relapseEvaluate predictorsInternational Robotic Cystectomy ConsortiumCox proportional regression analysisPort site recurrenceKaplan-Meier methodLymph node removalOncologic surgical principlesPeritoneal carcinomatosisNodal involvementPredictors of diseaseLocal recurrenceSite recurrencePneumoperitoneum pressureCystectomyMultivariate analysisSurgical principlesPatientsMultivariate modelDiseaseRelapseBenefits of robotic cystectomy with intracorporeal diversion for patients with low cardiorespiratory fitness: A prospective cohort study
Lamb B, Tan W, Eneje P, Bruce D, Jones A, Ahmad I, Sridhar A, Baker H, Briggs T, Hines J, Nathan S, Martin D, Stephens R, Kelly J. Benefits of robotic cystectomy with intracorporeal diversion for patients with low cardiorespiratory fitness: A prospective cohort study. Urologic Oncology Seminars And Original Investigations 2016, 34: 417.e17-417.e23. PMID: 27197920, DOI: 10.1016/j.urolonc.2016.04.006.Peer-Reviewed Original ResearchConceptsCardiopulmonary exercise testing measurementsCardiopulmonary exercise testingHospital length of stayLength of stayProspective cohort studyRadical cystectomyCardiorespiratory fitnessAnaerobic thresholdRobotic cystectomyIntracorporeal diversionCohort studyIncreased hospital LOSInstitution prospective cohort studyHigh-grade bladder cancerPreoperative cardiopulmonary exercise testingRobotic radical cystectomyLow cardiorespiratory fitnessPoor cardiorespiratory fitnessReduced cardiorespiratory fitnessBody mass indexAbsence of control groupsOpen surgeryPatient demographicsBladder cancerCystectomyEvolution of the neobladder: A critical review of open and intracorporeal neobladder reconstruction techniques
Tan W, Lamb B, Kelly J. Evolution of the neobladder: A critical review of open and intracorporeal neobladder reconstruction techniques. Scandinavian Journal Of Urology 2016, 50: 95-103. PMID: 26882458, DOI: 10.3109/21681805.2016.1141318.Peer-Reviewed Original ResearchConceptsNeobladder reconstructionRadical cystectomyRobotic cystectomyPatient selectionOrthotopic bladder reconstructionMinimally invasive cystectomyIntracorporeal neobladder reconstructionMini-laparotomyOrthotopic neobladderIleal conduitCystectomySurgical techniqueMEDLINE searchBladder reconstructionIntracorporeal approachNeobladderKeyword search criteriaIntracorporealRobotic platformPatients
2015
Complications of Radical Cystectomy and Orthotopic Reconstruction
Tan W, Lamb B, Kelly J. Complications of Radical Cystectomy and Orthotopic Reconstruction. Advances In Urology 2015, 2015: 323157. PMID: 26697063, PMCID: PMC4677163, DOI: 10.1155/2015/323157.Peer-Reviewed Original ResearchOrthotopic bladder substitutionComplications of radical cystectomyRadical cystectomyUrinary diversionIleal orthotopic bladder substitutionShorter length of hospital stayLength of hospital stayHigh-volume institutionsLow-volume institutionsEnhanced recovery pathwayOncological surveillanceEarly complicationsBladder substitutionSignificant morbidityHospital stayCystectomyFollow-upComplicationsMorbidityEnhanced recoveryMortalitySurgeryPatientsRecovery pathwaysShorter length
2014
Loss of expression of the tumour suppressor gene AIMP3 predicts survival following radiotherapy in muscle‐invasive bladder cancer
Gurung P, Veerakumarasivam A, Williamson M, Counsell N, Douglas J, Tan W, Feber A, Crabb S, Short S, Freeman A, Powles T, Hoskin P, West C, Kelly J. Loss of expression of the tumour suppressor gene AIMP3 predicts survival following radiotherapy in muscle‐invasive bladder cancer. International Journal Of Cancer 2014, 136: 709-720. PMID: 24917520, DOI: 10.1002/ijc.29022.Peer-Reviewed Original ResearchConceptsMuscle-invasive bladder cancerMuscle-invasive bladder cancer patientsTissue-microarrayBladder cancerAssociated with survivalPredictive of survivalMethylation-specific PCRColony forming assayLoss of expressionRadical cystectomyRadiotherapy trialsRadiosensitising effectPrognostic valueMechanism of gene silencingRadiotherapyResponse to ionising radiationClinical biomarkersPatientsProtein expressionCancerMeta-analysisDNA damage responseCystectomySurvivalBladder